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. 1962 Sep;84(3):581–589. doi: 10.1128/jb.84.3.581-589.1962

EPISOMIC ELEMENT IN A STRAIN OF SALMONELLA TYPHOSA

Stanley Falkow 1, L S Baron 1
PMCID: PMC277918  PMID: 16561959

Abstract

Falkow, Stanley (Walter Reed Army Institute of Research, Washington, D.C.) and L. S. Baron. Episomic element in a strain of Salmonella typhosa. J. Bacteriol. 84:581–589. 1962.—An episomic element, F0-lac+, has been identified in a strain of Salmonella typhosa isolated from a natural habitat. The F0-lac+ element is transferred at high frequency as a single unit of transmission and replication without linkage to any other genetic character. Cells receiving F0-lac+ are heterogenotes as if F0-lac+ is not integrated as part of the linear structure of the chromosome, but rather replicates autonomously or in some other association with the genome. Evidence from complementation tests and transduction experiments is presented that the lac genes carried by F0 are identical or at least markedly similar to the lac genes of Escherichia coli K-12. The F0 transmission factor cannot be precisely identified but it does not appear to be phage or colicin. F0 does exhibit mutual repression with the sex factor, F, of E. coli, and immunological experiments indicate some relationship between F and F0.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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