Skip to main content
Journal of Bacteriology logoLink to Journal of Bacteriology
. 1962 Oct;84(4):859–863. doi: 10.1128/jb.84.4.859-863.1962

METABOLISM OF POLYAMINES BY STAPHYLOCOCCUS

Sanford M Rosenthal a, Donald T Dubin b,1
PMCID: PMC277968  PMID: 13974996

Abstract

Rosenthal, Sanford M. (National Institute of Arthritis and Metabolic Diseases, Bethesda, Md.) and Donald T. Dubin. Metabolism of polyamines by Staphylococcus. J. Bacteriol. 84:859–863. 1962—Although spermine and spermidine are not detectable in staphylococci grown in purified medium, considerable amounts (0.7 to 1.4 μmole/g wet wt) were demonstrated in cells grown in the presence of these amines. Conjugation of spermine, and to a lesser extent of spermidine, was demonstrated. Putrescine and cadaverine added to purified medium are not appreciably taken up by staphylococcal cells. However, high percentages were recovered in the medium in conjugated form. These conjugates were shown to be monoacetylputrescine and probably monoacetylcadaverine. Meat infusion broth, neopeptone, spermine, and spermidine were highly inhibitory to this acetylation. No evidence of utilization of these polyamines was obtained.

Full text

PDF
859

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. DUBIN D. T., ROSENTHAL S. M. The acetylation of polyamines in Escherichia coli. J Biol Chem. 1960 Mar;235:776–782. [PubMed] [Google Scholar]
  2. HERBST E. J., WEAVER R. H., KEISTER D. L. The gram reaction and cell composition: diamines and polyamines. Arch Biochem Biophys. 1958 May;75(1):171–177. doi: 10.1016/0003-9861(58)90407-7. [DOI] [PubMed] [Google Scholar]
  3. ROSE I. A., GRUNBERG-MANAGO M., KOREY S. R., OCHOA S. Enzymatic phosphorylation of acetate. J Biol Chem. 1954 Dec;211(2):737–756. [PubMed] [Google Scholar]
  4. ROSENTHAL S. M., TABOR C. W. The pharmacology of spermine and spermidine; distribution and excretion. J Pharmacol Exp Ther. 1956 Feb;116(2):131–138. [PubMed] [Google Scholar]
  5. TABOR H., ROSENTHAL S. M., TABOR C. W. The biosynthesis of spermidine and spermine from putrescine and methionine. J Biol Chem. 1958 Oct;233(4):907–914. [PubMed] [Google Scholar]
  6. WEAVER R. H., HERBST E. J. Metabolism of diamines and polyamines in microorganisms. J Biol Chem. 1958 Apr;231(2):637–646. [PubMed] [Google Scholar]

Articles from Journal of Bacteriology are provided here courtesy of American Society for Microbiology (ASM)

RESOURCES