Skip to main content
Journal of Bacteriology logoLink to Journal of Bacteriology
. 1963 Jan;85(1):49–52. doi: 10.1128/jb.85.1.49-52.1963

INFLUENCE OF STREPTOMYCIN ON NUCLEOTIDE EXCRETION IN ESCHERICHIA COLI

Helen Tzagoloff 1, W W Umbreit 1
PMCID: PMC278088  PMID: 13995057

Abstract

Tzagoloff, Helen (Rutgers, The State University, New Brunswick, N.J.) and W. W. Umbreit. Influence of streptomycin on nucleotide excretion in Escherichia coli. J. Bacteriol. 85:49–52. 1963.—The action of streptomycin in causing nucleotide excretion is not the cause of the killing effect of streptomycin, because, in certain strains, streptomycin may kill the cells without evidence of nucleotide excretion. In readily excreting strains, most of the cells are killed before nucleotide excretion is evident.

Full text

PDF
49

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. ANAND N., DAVIS B. D., ARMITAGE A. K. Uptake of streptomycin by Escherichia coli. Nature. 1960 Jan 2;185:23–24. doi: 10.1038/185023a0. [DOI] [PubMed] [Google Scholar]
  2. ANAND N., DAVIS B. D. Damage by streptomycin to the cell membrane of Escherichia coli. Nature. 1960 Jan 2;185:22–23. doi: 10.1038/185022a0. [DOI] [PubMed] [Google Scholar]
  3. DAVIS B. D., MINGIOLI E. S. Mutants of Escherichia coli requiring methionine or vitamin B12. J Bacteriol. 1950 Jul;60(1):17–28. doi: 10.1128/jb.60.1.17-28.1950. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. DUBIN D. T., DAVIS B. D. The effect of streptomycin on potassium flux in Escherichia coli. Biochim Biophys Acta. 1961 Sep 16;52:400–402. doi: 10.1016/0006-3002(61)90697-7. [DOI] [PubMed] [Google Scholar]
  5. PLOTZ P. H., DAVIS B. D. Absence of a chloramphenicol-insensitive phase of streptomycin action. J Bacteriol. 1962 Apr;83:802–805. doi: 10.1128/jb.83.4.802-805.1962. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. PLOTZ P. H., DAVIS B. D. Synergism between streptomycin and penicillin: a proposed mechanism. Science. 1962 Mar 23;135(3508):1067–1068. doi: 10.1126/science.135.3508.1067. [DOI] [PubMed] [Google Scholar]
  7. PLOTZ P. H., DUBIN D. T., DAVIS B. D. Influence of salts on the uptake of streptomycin by Escherichia coli. Nature. 1961 Sep 23;191:1324–1325. doi: 10.1038/1911324a0. [DOI] [PubMed] [Google Scholar]
  8. ROSANO C. L., PEABODY R. A., HURWITZ C. Studies on the mechanism of action of action of streptomycin. Effect of streptomycin on the excretion of nucleotides by Escherichia coli. Biochim Biophys Acta. 1960 Jan 15;37:380–382. doi: 10.1016/0006-3002(60)90261-4. [DOI] [PubMed] [Google Scholar]
  9. ROTH H., AMOS H., DAVIS B. D. Purine nucleotide excretion by Escherichia coli in the presence of streptomycin. Biochim Biophys Acta. 1960 Jan 29;37:398–405. doi: 10.1016/0006-3002(60)90495-9. [DOI] [PubMed] [Google Scholar]

Articles from Journal of Bacteriology are provided here courtesy of American Society for Microbiology (ASM)

RESOURCES