Abstract
Maurer, P. R. (University of Otago Medical School, Dunedin, New Zealand) and R. D. Batt. Oxidation of polyols by Nocardia corallina. J. Bacteriol. 83:1131–1139. 1962.—Two diphosphopyridine nucleotide-linked polyol dehydrogenases were induced in Nocardia corallina strain S, and grown on either mannitol or sorbitol. One enzyme was labile and was specific for the conversion of sorbitol to d-fructose.
The second enzyme, which converted d-mannitol to d-fructose and, more slowly, d-arabitol to d-xylulose, was named the d-mannitol dehydrogenase. The configurations of the hydroxyl groups at carbons 2, 3, 4, and 5 of substrates for this enzyme were stereospecific. Formation of the enzyme was induced by d-mannitol and d-sorbitol but not by d-arabitol.
Extracts of cells grown on either mannitol or sorbitol catalyzed the oxidation of the reduced form of diphosphopyridine nucleotide in the presence of d-fructose and d-xylulose.
Cell suspensions of the organism oxidized mannitol, sorbitol, glycerol, inositol, and fructose but not dulcitol, d-arabitol, d-xylulose, or l-sorbose.
Full text
PDFSelected References
These references are in PubMed. This may not be the complete list of references from this article.
- ARCUS A. C., EDSON N. L. Polyol dehydrogenases. 2. The polyol dehydrogenases of Acetobacter suboxydans and Candida utilis. Biochem J. 1956 Nov;64(3):385–394. doi: 10.1042/bj0640385. [DOI] [PMC free article] [PubMed] [Google Scholar]
- BATT R. D. Induction of enzymes for pyrimidine catabolism in Nocardia corallina. J Bacteriol. 1961 Jan;81:59–64. doi: 10.1128/jb.81.1.59-64.1961. [DOI] [PMC free article] [PubMed] [Google Scholar]
- BATT R. D., WOODS D. D. Decomposition of pyrimidines by Nocardia corallina. J Gen Microbiol. 1961 Feb;24:207–224. doi: 10.1099/00221287-24-2-207. [DOI] [PubMed] [Google Scholar]
- BEVENUE A., WILLIAMS K. T. Further evidence indicating the specificity of the orcinol spray reagent for ketoheptoses on paper chromatograms. Arch Biochem Biophys. 1951 Nov;34(1):225–227. doi: 10.1016/s0003-9861(51)80032-8. [DOI] [PubMed] [Google Scholar]
- CAVALLINI D. The coupled oxidation of pyruvate with glutathione and cysteine. Biochem J. 1951 Jun;49(1):1–5. doi: 10.1042/bj0490001. [DOI] [PMC free article] [PubMed] [Google Scholar]
- LIN E. C. An inducible D-arabitol dehydrogenase from Aerobacter aerogenes. J Biol Chem. 1961 Jan;236:31–36. [PubMed] [Google Scholar]
- MARCUS L., MARR A. G. Polyol dehydrogenases of Azotobacter agilis. J Bacteriol. 1961 Aug;82:224–232. doi: 10.1128/jb.82.2.224-232.1961. [DOI] [PMC free article] [PubMed] [Google Scholar]
- MONOD J., COHN M. La biosynthèse induite des enzymes; adaptation enzymatique. Adv Enzymol Relat Subj Biochem. 1952;13:67–119. [PubMed] [Google Scholar]
- McCLUNG N. M. The utilization of carbon compounds by Nocardia species. J Bacteriol. 1954 Aug;68(2):231–236. doi: 10.1128/jb.68.2.231-236.1954. [DOI] [PMC free article] [PubMed] [Google Scholar]
- McCORKINDALE J., EDSON N. L. Polyol dehydrogenases. I. The specificity of rat-liver polyol dehydrogenase. Biochem J. 1954 Jul;57(3):518–523. doi: 10.1042/bj0570518. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Midwinter G. G., Batt R. D. ENDOGENOUS RESPIRATION AND OXIDATIVE ASSIMILATION IN NOCARDIA CORALLINA. J Bacteriol. 1960 Jan;79(1):9–17. doi: 10.1128/jb.79.1.9-17.1960. [DOI] [PMC free article] [PubMed] [Google Scholar]
- SEBEK O. K., RANDLES C. I. The oxidative dissimilation of mannitol and sorbitol by Pseudomonas fluorescens. J Bacteriol. 1952 Jun;63(6):693–700. doi: 10.1128/jb.63.6.693-700.1952. [DOI] [PMC free article] [PubMed] [Google Scholar]
- TOUSTER O., SHAW D. R. Biochemistry of the acyclic polyols. Physiol Rev. 1962 Apr;42:181–225. doi: 10.1152/physrev.1962.42.2.181. [DOI] [PubMed] [Google Scholar]
- WOOD W. A., McDONOUGH M. J., JACOBS L. B. Rihitol and D-arabitol utilization by Aerobacter aerogenes. J Biol Chem. 1961 Aug;236:2190–2195. [PubMed] [Google Scholar]