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. 1993 Dec;61(12):5410–5412. doi: 10.1128/iai.61.12.5410-5412.1993

Class II major histocompatibility complex molecule expression on murine eosinophils activated in vivo by Brugia malayi.

S D Mawhorter 1, E Pearlman 1, J W Kazura 1, W H Boom 1
PMCID: PMC281333  PMID: 7901170

Abstract

The Th-2 response to microfilariae of Brugia malayi in BALB/c mice is associated with peritoneal eosinophilia. These eosinophils had an activated hypodense phenotype in vivo and expressed high levels of the class II major histocompatibility complex (MHC). Interleukin 4 up-regulated the class II MHC, whereas gamma interferon inhibited class II MHC expression on eosinophils.

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Selected References

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