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. 1988 Dec;85(24):9851–9855. doi: 10.1073/pnas.85.24.9851

Characterization and cDNA cloning of the pheromone-binding protein from the tobacco hornworm, Manduca sexta: a tissue-specific developmentally regulated protein.

T K Györgyi 1, A J Roby-Shemkovitz 1, M R Lerner 1
PMCID: PMC282879  PMID: 3200861

Abstract

cDNA encoding pheromone-binding protein (PBP), the major soluble protein in olfactory sensilla of male moths, has been cloned from the tobacco hornworm, Manduca sexta. A study of the developmental time course of PBP reveals that it is first synthesized just prior to eclosion and that the percentage of antennal mRNA encoding PBP shifts from zero to about 20% at that time. PBP is also found in sensilla from female M. sexta antennae. No amino acid sequence homology is observed between PBP and the vertebrate odorant-binding protein.

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Selected References

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