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. 1970 Mar;65(3):551–556. doi: 10.1073/pnas.65.3.551

Cellular Sites of Immunologic Unresponsiveness*

Jacques M Chiller 1,†, Gail S Habicht 1, William O Weigle 1,‡
PMCID: PMC282942  PMID: 4192271

Abstract

The reconstitution of the immune response of lethally irradiated mice to human γ-globulin is dependent on the synergistic action of bone marrow with thymus cells. Immunologic unresponsiveness appears to involve a functional defect at each of these cellular levels, inasmuch as neither bone marrow nor thymus cells from unresponsive donors are capable of demonstrating synergism in combination with their normal counterpart.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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