Abstract
Mutants of the maroon-like complex, representative of the five known complementation classes, were subjected to fine structure mapping experiments utilizing a nutritional selective procedure which permits the survival of rare ma-l+ progeny from large-scale crosses. The analysis provides an internally consistent, unique map, colinear with the complementation map. Noncomplementers exhibit a polarized mapping distribution. In addition to ma-l+ recombinants, the selective medium permitted the survival of ma-l+ exceptionals not associated with recombination for adjacent markers. Analysis of the exceptionals favors their origin as convertants.
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Selected References
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- Chovnick A., Finnertty V., Schalet A., Duck P. Studies on genetic organization in higher organisms. I. Analysis of a complex gene in Drosophila melanogaster. Genetics. 1969 May;62(1):145–160. doi: 10.1093/genetics/62.1.145. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Chovnick A. Genetic organization in higher organisms. Proc R Soc Lond B Biol Sci. 1966 Mar 22;164(995):198–208. doi: 10.1098/rspb.1966.0023. [DOI] [PubMed] [Google Scholar]
- Glassman E. Genetic regulation of xanthine dehydrogenase in Drosophila melanogaster. Fed Proc. 1965 Sep-Oct;24(5):1243–1251. [PubMed] [Google Scholar]
- Heathcote J. G., Washington R. J. A simple quantitative method for the determination of small amounts of amino-acids. Analyst. 1967 Oct;92(99):627–633. doi: 10.1039/an9679200627. [DOI] [PubMed] [Google Scholar]
- LISSOUBA P., RIZET G. [On the existence of a polarized genetic unit which does not undergo non-reciprocal exchanges]. C R Hebd Seances Acad Sci. 1960 May 16;250:3408–3410. [PubMed] [Google Scholar]
- Welshons W. J. Analysis of a gene in drosophila. Science. 1965 Nov 26;150(3700):1122–1129. doi: 10.1126/science.150.3700.1122. [DOI] [PubMed] [Google Scholar]