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. 1970 Jun;66(2):314–321. doi: 10.1073/pnas.66.2.314

A Cell-Associated Factor Essential for Formation of an Infectious Form of Rous Sarcoma Virus*

H Hanafusa 1, T Miyamoto 1, T Hanafusa 1
PMCID: PMC283046  PMID: 4317912

Abstract

Formation of a specific type of infectious Rous sarcoma virus called RSV(0) has been found to occur only in a certain type of chick embryo cell in the absence of avian leukosis virus. Although these chick cells lack any complete form of avian leukovirus, they appear to carry a genetic factor essential for formation of infectious RSV(0). A factor-deficient cell can be converted to a producer of infectious RSV(0) by infection with Rous sarcoma virus or avian leukosis virus which has been grown in factor-containing cells. Evidence is presented to show that the factor determines both the antigenic and host range specificity of RSV(0).

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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