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Proceedings of the National Academy of Sciences of the United States of America logoLink to Proceedings of the National Academy of Sciences of the United States of America
. 1970 Dec;67(4):1834–1838. doi: 10.1073/pnas.67.4.1834

DNA-Induced Transformation in Drosophila: Evidence for Transmission without Integration*

Allen S Fox 1, William F Duggleby 1,†,, William M Gelbart 1,, Sei Byung Yoon 1
PMCID: PMC283436  PMID: 5275381

Abstract

A key feature of the exosome model of transformation in Drosophila melanogaster is that the DNA segments responsible for the phenomenon are not integrated into the linear structure of the chromosomes. This feature is confirmed by the failure to find whole-body transformants in a series of large-scale experiments, and by the absence of evidence for integration under conditions favoring genetic exchange between chromosomes and introduced DNA.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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