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. 1994 Oct;38(10):2498–2501. doi: 10.1128/aac.38.10.2498

Ability of cecropin B to penetrate the enterobacterial outer membrane.

M Vaara 1, T Vaara 1
PMCID: PMC284773  PMID: 7840597

Abstract

The cationic amphipathic insect peptide cecropin B was almost as active on wild-type enteric bacteria as it was on their lipopolysaccharide and lipid A mutants that have very defective outer membrane. The polymyxin-resistant strains, which elaborate altered, less anionic lipopolysaccharide, were completely susceptible to cecropin B. No synergism was found between cecropin B and hydrophobic antibiotics. Throughout the study, the activity of cecropin B resembled that of quaternary detergents.

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Selected References

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