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Proceedings of the National Academy of Sciences of the United States of America logoLink to Proceedings of the National Academy of Sciences of the United States of America
. 1989 Mar;86(6):2021–2025. doi: 10.1073/pnas.86.6.2021

Comparison of a human T-cell lymphotropic virus type I strain from cerebrospinal fluid of a Jamaican patient with tropical spastic paraparesis with a prototype human T-cell lymphotropic virus type I.

P S Sarin 1, P Rodgers-Johnson 1, D K Sun 1, A H Thornton 1, O S Morgan 1, W N Gibbs 1, C Mora 1, G McKhann 2nd 1, D C Gajdusek 1, C J Gibbs Jr 1
PMCID: PMC286838  PMID: 2467295

Abstract

The isolation and characterization of a human T-cell lymphotropic retrovirus related to human T-cell lymphotropic virus type I (HTLV-I) from cerebrospinal fluid of a Jamaican patient with tropical spastic paraparesis is described. The virus isolate is a typical type C retrovirus as seen by electron microscopy and is related to prototype HTLV-I isolated from patients with adult T-cell leukemia but is not identical to this prototype HTLV-I as seen by restriction enzyme mapping.

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Selected References

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