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Proceedings of the National Academy of Sciences of the United States of America logoLink to Proceedings of the National Academy of Sciences of the United States of America
. 1989 May;86(9):3003–3005. doi: 10.1073/pnas.86.9.3003

Estimating the superiority of a drug to a placebo when all and only those patients at risk are treated with the drug.

H Robbins 1, C H Zhang 1
PMCID: PMC287052  PMID: 2717608

Abstract

It is shown that, under certain assumptions, one can estimate the difference between the effect of a treatment and that of a placebo even when the treatment has been given to all and only those patients who are at risk (as evidenced by a screening examination).

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Robbins H., Zhang C. H. Estimating a treatment effect under biased sampling. Proc Natl Acad Sci U S A. 1988 Jun;85(11):3670–3672. doi: 10.1073/pnas.85.11.3670. [DOI] [PMC free article] [PubMed] [Google Scholar]

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