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. 1980 May;34(2):490–496. doi: 10.1128/jvi.34.2.490-496.1980

mRNA capping enzymes are masked in reovirus progeny subviral particles.

D Skup, S Millward
PMCID: PMC288728  PMID: 6246277

Abstract

We examined the enzyme activities associated with progeny subviral particles isolated from L-cells infected with reovirus at 12 h postinfection. Activities normally present in reovirus cores were also found to be present in the progeny subviral particles, with the exception of the capping enzymes. The methylase and guanyl transferase activities, which constitute the capping system, were present in a masked form that could be activated by chymotrypsin digestion. The appearance of these progeny subviral particles in infected cells coincided with the time when mRNA synthesis was maximal, suggesting that viral mRNA synthesized at later times is uncapped.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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