Skip to main content
Journal of Virology logoLink to Journal of Virology
. 1980 May;34(2):576–581. doi: 10.1128/jvi.34.2.576-581.1980

Biochemical characterization of endogenous type C virus information in differentiated and undifferentiated murine teratocarcinoma-derived cell lines.

R Emanoil-Ravicovitch, F Hojman-Montes-de-Oca, J Robert, M Garcette, R Callahan, J Peries, M Boiron
PMCID: PMC288739  PMID: 6246284

Abstract

Undifferentiated teratocarcinoma cells express sixfold-higher levels of endogenous xenotropic type C virus-related RNA than differentiated cells. Three species of polyadenylated viral RNA (35S, 24S, and 14S) have been identified in the undifferentiated teratocarcinoma cells. Paradoxically, neither viral particles nor viral proteins have been detected in these cells.

Full text

PDF
581

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Benveniste R. E., Scolnick E. M. RNA in mammalian sarcoma virus transformed nonproducer cells homologous to murine leukemia virus RNA. Virology. 1973 Feb;51(2):370–382. doi: 10.1016/0042-6822(73)90436-4. [DOI] [PubMed] [Google Scholar]
  2. Biczysko W., Pienkowski M., Solter D., Koprowski H. Virus particles in early mouse embryos. J Natl Cancer Inst. 1973 Sep;51(3):1041–1050. doi: 10.1093/jnci/51.3.1041. [DOI] [PubMed] [Google Scholar]
  3. Callahan R., Benveniste R. E., Lieber M. M., Todaro G. J. Nucleic acid homology of murine type-C viral genes. J Virol. 1974 Dec;14(6):1394–1403. doi: 10.1128/jvi.14.6.1394-1403.1974. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Chattopadhyay S. K., Lowy D. R., Teich N. M., Levine A. S., Rowe W. P. Qualitative and quantitative studies of AKR-type murine leukemia virus sequences in mouse DNA. Cold Spring Harb Symp Quant Biol. 1975;39(Pt 2):1085–1101. doi: 10.1101/sqb.1974.039.01.124. [DOI] [PubMed] [Google Scholar]
  5. Emanoil-Ravicovitch R., Larsen C. J., Bazilier M., Robin J., Périès J., Boiron M. Low-molecular-weight RNAs of murine sarcoma virus: comparative studies of free and 70S RNA-associated components. J Virol. 1973 Dec;12(6):1625–1627. doi: 10.1128/jvi.12.6.1625-1627.1973. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. Fan H., Baltimore D. RNA metabolism of murine leukemia virus: detection of virus-specific RNA sequences in infected and uninfected cells and identification of virus-specific messenger RNA. J Mol Biol. 1973 Oct 15;80(1):93–117. doi: 10.1016/0022-2836(73)90235-0. [DOI] [PubMed] [Google Scholar]
  7. Fan H., Verma I. M. Size analysis and relationship of murine leukemia virus-specific mRNA's: evidence for transposition of sequences during synthesis and processing of subgenomic mRNA. J Virol. 1978 May;26(2):468–478. doi: 10.1128/jvi.26.2.468-478.1978. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. Levy J. A. Endogenous C-type viruses: double agents in natural life processes. Biomedicine. 1976 May;24(2):84–93. [PubMed] [Google Scholar]
  9. Nicolas J. F., Avner P., Gaillard J., Guenet J. L., Jakob H., Jacob F. Cell lines derived from teratocarcinomas. Cancer Res. 1976 Nov;36(11 Pt 2):4224–4231. [PubMed] [Google Scholar]
  10. Paterson B. M., Rosenberg M. Efficient translation of prokaryotic mRNAs in a eukaryotic cell-free system requires addition of a cap structure. Nature. 1979 Jun 21;279(5715):692–696. doi: 10.1038/279692a0. [DOI] [PubMed] [Google Scholar]
  11. Teich N. M., Weiss R. A., Martin G. R., Lowy D. R. Virus infection of murine teratocarcinoma stem cell lines. Cell. 1977 Dec;12(4):973–982. doi: 10.1016/0092-8674(77)90162-3. [DOI] [PubMed] [Google Scholar]
  12. Vernon M. L., Lane W. T., Huebner R. J. Prevalence of type-C particles in visceral tissues of embryonic and newborn mice. J Natl Cancer Inst. 1973 Oct;51(4):1171–1175. doi: 10.1093/jnci/51.4.1171. [DOI] [PubMed] [Google Scholar]
  13. Wetmur J. G., Davidson N. Kinetics of renaturation of DNA. J Mol Biol. 1968 Feb 14;31(3):349–370. doi: 10.1016/0022-2836(68)90414-2. [DOI] [PubMed] [Google Scholar]
  14. Zaane D. V., Gielkens A. L., Hesselink W. G., Bloemers H. P. Identification of Rauscher murine leukemia virus-specific mRNAs for the synthesis of gag- and env-gene products. Proc Natl Acad Sci U S A. 1977 May;74(5):1855–1859. doi: 10.1073/pnas.74.5.1855. [DOI] [PMC free article] [PubMed] [Google Scholar]

Articles from Journal of Virology are provided here courtesy of American Society for Microbiology (ASM)

RESOURCES