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. 1963 Apr;42(4):516–524. doi: 10.1172/JCI104740

IN VIVO AND IN VITRO STUDIES OF ADRENAL SECRETIONS IN CUSHING'S SYNDROME AND PRIMARY ALDOSTERONISM*

Edward G Biglieri 1, Satoshi Hane 1, Paul E Slaton Jr 1, Peter H Forsham 1
PMCID: PMC289311  PMID: 13971125

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. BAILEY R. E., SLADE C. I., LIEBERMAN A. H., LUETSCHER J. A., Jr Steroid production by human adrenal adenomata and nontumorous adrenal tissue in vitro. J Clin Endocrinol Metab. 1960 Mar;20:457–465. doi: 10.1210/jcem-20-3-457. [DOI] [PubMed] [Google Scholar]
  2. BARTTER F. C., DUNCAN L. E., Jr, LIDDLE G. W. Dual mechanism regulating adrenocortical function in man. Am J Med. 1956 Sep;21(3):380–386. doi: 10.1016/0002-9343(56)90038-9. [DOI] [PubMed] [Google Scholar]
  3. BAULIEU E. E., ROBEL P., SIGUIER F., JAYLE M. F. Metabolic observations in a case of pure primary hyperaldosteronism. J Clin Endocrinol Metab. 1959 Sep;19:1081–1102. doi: 10.1210/jcem-19-9-1081. [DOI] [PubMed] [Google Scholar]
  4. BECK J. C., DYRENFURTH I., VENNING E. H. Effect of corticotropin and prednisone on the excretion of aldosterone in man. J Clin Endocrinol Metab. 1956 Dec;16(12):1541–1553. doi: 10.1210/jcem-16-12-1541. [DOI] [PubMed] [Google Scholar]
  5. CHRISTY N. P., LARAGH J. H. Pathogenesis of hypokalemic alkalosis in Cushing's syndrome. N Engl J Med. 1961 Nov 30;265:1083–1088. doi: 10.1056/NEJM196111302652203. [DOI] [PubMed] [Google Scholar]
  6. COLSKY J., FINE D., MEISELAS L. E., OXENHORN S. Primary aldosteronism; report of a case and discussion of the pathogenesis. N Engl J Med. 1957 Jan 24;256(4):147–152. doi: 10.1056/NEJM195701242560401. [DOI] [PubMed] [Google Scholar]
  7. COPE C. L., BLACK E. G. The behaviour of 14c-cortisol and estimation of cortisol production rate in man. Clin Sci. 1958 Feb;17(1):147–163. [PubMed] [Google Scholar]
  8. DELORME P., GENEST J. Primary aldosteronism. A review of medical literature from 1955 to June 1958. Can Med Assoc J. 1959 Dec 1;81:893–902. [PMC free article] [PubMed] [Google Scholar]
  9. DYRENFURTH I., BLAIR A. J., BECK J. C., VENNING E. H. Studies in patients with adrenocortical hyperfunction. I. The effect of corticotropin on levels of corticosteroids, 17-ketosteroids and aldosterone. J Clin Endocrinol Metab. 1960 May;20:735–750. doi: 10.1210/jcem-20-5-735. [DOI] [PubMed] [Google Scholar]
  10. DYRENFURTH I., LUCIS O. J., BECK J. C., VENNING E. H. Studies in patients with adrenocortical hyperfunction. III. IN vitro secretion of steroids by human adrenal glands. J Clin Endocrinol Metab. 1960 May;20:765–779. doi: 10.1210/jcem-20-5-765. [DOI] [PubMed] [Google Scholar]
  11. FLOOD C., LAYNE D. S., RAMCHARAN S., ROSSIPAL E., TAIT J. F., TAIT S. A. An investigation of the urinary metabolites and secretion rates of aldosterone and cortisol in man and a description of methods for their measurement. Acta Endocrinol (Copenh) 1961 Feb;36:237–264. doi: 10.1530/acta.0.0360237. [DOI] [PubMed] [Google Scholar]
  12. GOLDSMITH R. S., MERONEY W. H., BARTTER F. C. Prominent peripheral edema associated with primary aldosteronism due to an adrenocortical adenoma. J Clin Endocrinol Metab. 1960 Aug;20:1168–1183. doi: 10.1210/jcem-20-8-1168. [DOI] [PubMed] [Google Scholar]
  13. HERNANDO L., CRABBE J., ROSS E. J., REDDY W. J., RENOLD A. E., NELSON D. H., THORN G. W. Clinical experience with a physicochemical method for estimation of aldosterone in urine. Metabolism. 1957 Nov;6(6 Pt 1):518–543. [PubMed] [Google Scholar]
  14. KLIMAN B., PETERSON R. E. Double isotope derivative assay of aldosterone in biological extracts. J Biol Chem. 1960 Jun;235:1639–1648. [PubMed] [Google Scholar]
  15. MADER I. J., ISERI L. T. Spontaneous hypopotassemia, hypomagnesemia, alkalosis and tetany due to hypersecretion of corticosterone-like mineralocorticoid. Am J Med. 1955 Dec;19(6):976–988. doi: 10.1016/0002-9343(55)90164-9. [DOI] [PubMed] [Google Scholar]
  16. MULROW P. J., COHN G. L. Corticosteroid release and synthesis in vitro by adrenal slices from patients with Cushing's syndrome. J Clin Invest. 1961 Jul;40:1250–1262. doi: 10.1172/JCI104355. [DOI] [PMC free article] [PubMed] [Google Scholar]
  17. ORNDAHL G., HOKFELT B., LJUNGGREN E., HOOD B. Two cases of primary aldosteronism. Comments on differential diagnosis and difficulties in screening. Acta Med Scand. 1959 Dec 28;165:445–452. [PubMed] [Google Scholar]
  18. PETERSON R. E., PIERCE C. E. The metabolism of corticosterone in man. J Clin Invest. 1960 May;39:741–757. doi: 10.1172/JCI104091. [DOI] [PMC free article] [PubMed] [Google Scholar]
  19. REDDY W. J., JENKINS D., THORN G. W. Estimation of 17-hydroxycorticoids in urine. Metabolism. 1952 Nov;1(6):511–527. [PubMed] [Google Scholar]
  20. SKANSE B., MOLLER F., GYDELL K., JOHANSSON S., WULFF H. B. Observations on primary aldosteronism. Acta Med Scand. 1957 Sep 6;158(3-4):181–192. doi: 10.1111/j.0954-6820.1957.tb15481.x. [DOI] [PubMed] [Google Scholar]
  21. VESTERGAARD P. Rapid micro-modification of the Zimmermann/Callow procedure for the determination of 17-ketosteroids in urine. Acta Endocrinol (Copenh) 1951;8(3):193–214. doi: 10.1530/acta.0.0080193. [DOI] [PubMed] [Google Scholar]

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