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. 1963 Oct;42(10):1542–1551. doi: 10.1172/JCI104839

STUDIES ON THE COUMARIN ANTICOAGULANT DRUGS: THE PHARMACODYNAMICS OF WARFARIN IN MAN*

Robert A O'Reilly 1,2, Paul M Aggeler 1,2, Lois S Leong 1,2
PMCID: PMC289433  PMID: 14074349

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. BERSON S. A., YALOW R. S., SCHREIBER S. S., POST J. Tracer experiments with I131 labeled human serum albumin: distribution and degradation studies. J Clin Invest. 1953 Aug;32(8):746–768. doi: 10.1172/JCI102789. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. GREEN J. P., SONDERGAARD E., DAM H. Studies on disturbution of dicumarol. Proc Soc Exp Biol Med. 1956 Jun;92(2):449–451. doi: 10.3181/00379727-92-22506. [DOI] [PubMed] [Google Scholar]
  3. HOLMES R. W., LOVE J. Suicide attempt with warfarin, a bishydroxycoumarin-like rodenticide. J Am Med Assoc. 1952 Mar 15;148(11):935–937. doi: 10.1001/jama.1952.62930110003013a. [DOI] [PubMed] [Google Scholar]
  4. LEE C. C., TREVOY L. W., SPINKS J. W. T., JAQUES L. B. Dicumarol labelled with C14. Proc Soc Exp Biol Med. 1950 May;74(1):151–155. doi: 10.3181/00379727-74-17838. [DOI] [PubMed] [Google Scholar]
  5. LINK K. P. The discovery of dicumarol and its sequels. Circulation. 1959 Jan;19(1):97–107. doi: 10.1161/01.cir.19.1.97. [DOI] [PubMed] [Google Scholar]
  6. NELSON E. Kinetics of drug absorption, distribution, metabolism, and excretion. J Pharm Sci. 1961 Mar;50:181–192. doi: 10.1002/jps.2600500302. [DOI] [PubMed] [Google Scholar]
  7. POLLOCK B. E. Clinical experience with warfarin (coumadin) sodium, a new anticoagulant. J Am Med Assoc. 1955 Nov 12;159(11):1094–1097. doi: 10.1001/jama.1955.02960280016004. [DOI] [PubMed] [Google Scholar]
  8. SHAPIRO S. Warfarin sodium derivative: (coumadin sodium); an intravenous hypoprothrombinemia-inducing agent. Angiology. 1953 Aug;4(4):380–390. doi: 10.1177/000331975300400410. [DOI] [PubMed] [Google Scholar]
  9. TOOHEY M. Clinical experience with warfarin sodium. Br Med J. 1958 Oct 11;2(5101):892–893. doi: 10.1136/bmj.2.5101.892. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. WANNTORP H. Studies on chemical determination of warfar in and coumachlor and their toxicity for dog and swine. Acta Pharmacol Toxicol (Copenh) 1959;16(Suppl 2):1–123. [PubMed] [Google Scholar]
  11. WEINER M., SHAPIRO S., AXELROD J., COOPER J. R., BRODIE B. B. The physiological disposition of dicumarol in man. J Pharmacol Exp Ther. 1950 Aug;99(41):409–420. [PubMed] [Google Scholar]

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