Skip to main content
PMC home page
The Journal of Clinical Investigation logoLink to The Journal of Clinical Investigation
. 1961 Jan;40(1):117–129. doi: 10.1172/JCI104224

GAMMA GLOBULIN COMPLEXES IN RHEUMATOID ARTHRITIS AND CERTAIN OTHER CONDITIONS

H G Kunkel 1, H J Müller-Eberhard 1, H H Fudenberg 1, T B Tomasi 1
PMCID: PMC290696  PMID: 13755149

Full text

PDF
119

Images in this article

118Image
on p.118
118Image
on p.118
118Image
on p.118
118Image
on p.118
119Image
on p.119
119Image
on p.119
120Image
on p.120
120Image
on p.120
121Image
on p.121
121Image
on p.121
121Image
on p.121
121Image
on p.121
122Image
on p.122
122Image
on p.122
123Image
on p.123
123Image
on p.123
123Image
on p.123
123Image
on p.123

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. CANN J. R., BROWN R. A., SINGER S. J., SHUMAKER J. B., Jr, KIRKWOOD J. G. Ultracentrifugal studies of gamma-globulins prepared by electrophoresis-convection. Science. 1951 Jul 13;114(2950):30–33. doi: 10.1126/science.114.2950.30. [DOI] [PubMed] [Google Scholar]
  2. CONRAD M. E., Jr, RAMOS H. S., HOWIE D. L., CROSBY W. H., Jr Waldenström's macroglobulinemia. Med Ann Dist Columbia. 1959 Apr;28(4):193–199. [PubMed] [Google Scholar]
  3. DEUTSCH H. F., MORTON J. I. Dissociation of human serum macroglobulins. Science. 1957 Mar 29;125(3248):600–601. doi: 10.1126/science.125.3248.600. [DOI] [PubMed] [Google Scholar]
  4. EDELMAN G. M., KUNKEL H. G., FRANKLIN E. C. Interaction of the rheumatoid factor with antigen-antibody complexes and aggregated gamma globulin. J Exp Med. 1958 Jul 1;108(1):105–120. doi: 10.1084/jem.108.1.105. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. FRANKLIN E. C., HOLMAN H. R., MULLER-EBERHARD H. J., KUNKEL H. G. An unusual protein component of high molecular weight in the serum of certain patients with rheumatoid arthritis. J Exp Med. 1957 May 1;105(5):425–438. doi: 10.1084/jem.105.5.425. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. FRANKLIN E. C., KUNKEL H. G., MULLER-EBERHARD H. J., HOLMAN H. R. Relation of high molecular weight proteins to the serological reactions in rheumatoid arthritis. Ann Rheum Dis. 1957 Sep;16(3):315–321. doi: 10.1136/ard.16.3.315. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. GRUBB R., LAURELL A. B. Hereditary serological human serum groups. Acta Pathol Microbiol Scand. 1956;39(6):390–398. doi: 10.1111/j.1699-0463.1956.tb05067.x. [DOI] [PubMed] [Google Scholar]
  8. HEIMER R., FEDERICO O. M., FREYBERG R. H. Purification of a rheumatoid factor. Proc Soc Exp Biol Med. 1958 Nov;99(2):381–384. doi: 10.3181/00379727-99-24357. [DOI] [PubMed] [Google Scholar]
  9. KUNKEL H. G., FRANKLIN E. C., MULLER-EBERHARD H. J. Studies on the isolation and characterization of the "rheumatoid factor". J Clin Invest. 1959 Feb;38(2):424–434. doi: 10.1172/JCI103817. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. Kekwick R. A. The serum proteins in multiple myelomatosis. Biochem J. 1940 Sep;34(8-9):1248–1257. doi: 10.1042/bj0341248. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. LOSPALLUTO J., ZIFF M. Chromatographic studies of the rheumatoid factor. J Exp Med. 1959 Aug 1;110(2):169–186. doi: 10.1084/jem.110.2.169. [DOI] [PMC free article] [PubMed] [Google Scholar]
  12. MULLER-EBERHARD H. J., KUNKEL H. G. Ultracentrifugal characteristics and carbohydrate content of macromolecular gamma-globulins. Clin Chim Acta. 1959 Mar;4(2):252–258. doi: 10.1016/0009-8981(59)90138-x. [DOI] [PubMed] [Google Scholar]
  13. PEDERSEN K. O. Size relationship among similar proteins; association and dissociation reactions of protein units. Cold Spring Harb Symp Quant Biol. 1950;14:140–152. doi: 10.1101/sqb.1950.014.01.018. [DOI] [PubMed] [Google Scholar]
  14. PETERMANN M. L., HAMILTON M. G., KORNGOLD L. Multiple-myeloma proteins. II. Ultracentrigugal and electrophoretic analysis of a paucidisperse myeloma globulin. Cancer. 1956 Jan-Feb;9(1):193–194. doi: 10.1002/1097-0142(195601/02)9:1<193::aid-cncr2820090120>3.0.co;2-l. [DOI] [PubMed] [Google Scholar]
  15. REES E. D., RESNER R. Dissociation of a human serum macroglobulin in acid buffer. Clin Chim Acta. 1959 Mar;4(2):272–275. doi: 10.1016/0009-8981(59)90141-x. [DOI] [PubMed] [Google Scholar]
  16. SEHON A. H., GYENES L., GORDON J., RICHTER M., ROSE B. Physico-chemical and immunologic studies on macroglobulins. J Clin Invest. 1957 Mar;36(3):456–467. doi: 10.1172/JCI103443. [DOI] [PMC free article] [PubMed] [Google Scholar]
  17. SLATER R. J., WARD S. M., KUNKEL H. G. Immunological relationships among the myeloma proteins. J Exp Med. 1955 Jan 1;101(1):85–108. doi: 10.1084/jem.101.1.85. [DOI] [PMC free article] [PubMed] [Google Scholar]
  18. WALLENIUS G., TRAUTMAN R., KUNKEL H. G., FRANKLIN E. C. Ultracentrifugal studies of major non-lipide electrophoretic components of normal human serum. J Biol Chem. 1957 Mar;225(1):253–267. [PubMed] [Google Scholar]
  19. WALLER M. V., VAUGHAN J. H. Use of anti-Rh sera for demonstrating agglutination activating factor in rheumatoid arthritis. Proc Soc Exp Biol Med. 1956 May;92(1):198–200. doi: 10.3181/00379727-92-22426. [DOI] [PubMed] [Google Scholar]
  20. WILLIAMS R. R., STEWART L. C., JENKINS J. C. Purification and isolation of rheumatoid factor. Proc Soc Exp Biol Med. 1958 Dec;99(3):554–555. doi: 10.3181/00379727-99-24417. [DOI] [PubMed] [Google Scholar]
  21. ZLOTNICK A. Macroglobulinemia of Waldenström. Am J Med. 1958 Mar;24(3):461–466. doi: 10.1016/0002-9343(58)90331-0. [DOI] [PubMed] [Google Scholar]

Articles from Journal of Clinical Investigation are provided here courtesy of American Society for Clinical Investigation

RESOURCES