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. 1961 Feb;40(2):295–301. doi: 10.1172/JCI104256

OBSERVATIONS ON THE PYROGENIC RESPONSE AND ITS APPLICATION TO THE BIOASSAY OF ENDOTOXIN

Willis R Keene 1,*, Harold R Silberman 1,, Maurice Landy 1
PMCID: PMC290722  PMID: 13752168

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. ATKINS E., WOOD W. B., Jr Studies on the pathogenesis of fever. I. The presence of transferable pyrogen in the blood stream following the injection of typhoid vaccine. J Exp Med. 1955 May 1;101(5):519–528. doi: 10.1084/jem.101.5.519. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. ATKINS E., WOOD W. B., Jr Studies on the pathogenesis of fever. II. Identification of an endogenous pyrogen in the blood stream following the injection of typhoid vaccine. J Exp Med. 1955 Nov 1;102(5):499–516. doi: 10.1084/jem.102.5.499. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. BENNETT I. L., Jr, BEESON P. B. Studies on the pathogenesis of fever. I. The effect of injection of extracts and suspensions of uninfected rabbit tissues upon the body temperature of normal rabbits. J Exp Med. 1953 Nov;98(5):477–492. doi: 10.1084/jem.98.5.477. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. BENNETT I. L., Jr, BEESON P. B. Studies on the pathogenesis of fever. II. Characterization of fever-producing substances from polymorphonuclear leukocytes and from the fluid of sterile exudates. J Exp Med. 1953 Nov;98(5):493–508. doi: 10.1084/jem.98.5.493. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. BENNETT I. L., Jr, CLUFF L. E. Bacterial pyrogens. Pharmacol Rev. 1957 Dec;9(4):427–479. [PubMed] [Google Scholar]
  6. BENNETT I. L., Jr, PETERSDORF R. G., KEENE W. R. Pathogenesis of fever: evidence for direct cerebral action of bacterial endotoxins. Trans Assoc Am Physicians. 1957;70:64–73. [PubMed] [Google Scholar]
  7. CRANSTON W. I., GOODALE F., Jr, SNELL E. S., WENDT F. Measurement of the human febrile response to a bacterial pyrogen. Clin Sci. 1956 Nov;15(4):485–489. [PubMed] [Google Scholar]
  8. DARE J. G., MOGEY G. A. Rabbit responses to human threshold doses of a bacterial pyrogen. J Pharm Pharmacol. 1954 May;6(5):325–332. doi: 10.1111/j.2042-7158.1954.tb10954.x. [DOI] [PubMed] [Google Scholar]
  9. DAWSON M., TODD J. P. The assay of bacterial pyrogens. J Pharm Pharmacol. 1952 Nov;4(11):972–979. doi: 10.1111/j.2042-7158.1952.tb13230.x. [DOI] [PubMed] [Google Scholar]
  10. GRANT R., WHALEN W. J. Latency of pyrogen fever; appearance of a fast-acting pyrogen in the blood of febrile animals and in plasma incubated with bacterial pyrogen. Am J Physiol. 1953 Apr;173(1):47–54. doi: 10.1152/ajplegacy.1953.173.1.47. [DOI] [PubMed] [Google Scholar]
  11. KING M. K., WOOD W. B., Jr Studies on the pathogenesis of fever. IV. The site of action of leucocytic and circulating endogenous pyrogen. J Exp Med. 1958 Feb 1;107(2):291–303. doi: 10.1084/jem.107.2.291. [DOI] [PMC free article] [PubMed] [Google Scholar]
  12. PETERSDORF R. G., KEENE W. R., BENNETT I. L., Jr Studies on the pathogenesis of fever. IX. Characteristics of endogenous serum pyrogen and mechanisms governing its release. J Exp Med. 1957 Dec 1;106(6):787–809. doi: 10.1084/jem.106.6.787. [DOI] [PMC free article] [PubMed] [Google Scholar]
  13. RATHGEB P., SYLVEN B. Fractionation studies on the tumor-necrotizing agent from Serratia marcescens (Shear's polysaccharide). J Natl Cancer Inst. 1954 Apr;14(5):1099–1108. [PubMed] [Google Scholar]

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