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. 1965 Feb;44(2):291–301. doi: 10.1172/JCI105143

The Response of Extracellular Hydrogen Ion Concentration to Graded Degrees of Chronic Hypercapnia: The Physiologic Limits of the Defense of pH*

William B Schwartz 1, Newton C Brackett Jr 1,, Jordan J Cohen 1,
PMCID: PMC292477  PMID: 14260169

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. BRACKETT N. C., Jr, COHEN J. J., SCHWARTZ W. B. CARBON DIOXIDE TITRATION CURVE OF NORMAL MAN. EFFECT OF INCREASING DEGREES OF ACUTE HYPERCAPNIA ON ACID-BASE EQUILIBRIUM. N Engl J Med. 1965 Jan 7;272:6–12. doi: 10.1056/NEJM196501072720102. [DOI] [PubMed] [Google Scholar]
  2. COHEN J. J., BRACKETT N. C., Jr, SCHWARTZ W. B. THE NATURE OF THE CARBON DIOXIDE TITRATION CURVE IN THE NORMAL DOG. J Clin Invest. 1964 May;43:777–786. doi: 10.1172/JCI104964. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. GIEBISCH G., BERGER L., PITTS R. F. The extrarenal response to acute acid-base disturbances of respiratory origin. J Clin Invest. 1955 Feb;34(2):231–245. doi: 10.1172/JCI103076. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. POLAK A., HAYNIE G. D., HAYS R. M., SCHWARTZ W. B. Effects of chronic hypercapnia on electrolyte and acid-base equilibrium. I. Adaptation. J Clin Invest. 1961 Jul;40:1223–1237. doi: 10.1172/JCI104353. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. ROBIN E. D. Abnormalities of acid-base regulation in chronic pulmonary disease, with special reference to hypercapnia and extracellular alkalosis. N Engl J Med. 1963 Apr 25;268:917–922. doi: 10.1056/NEJM196304252681703. [DOI] [PubMed] [Google Scholar]
  6. VAN YPERSELE DE STRIHOU C., GULYASSY P. F., SCHWARTZ W. B. Effects of chronic hypercapnia on electrolyte and acid-base equilibrium. III. Characteristics of the adaptive and recovery process as evaluated by provision of alkali. J Clin Invest. 1962 Dec;41:2246–2253. doi: 10.1172/JCI104683. [DOI] [PMC free article] [PubMed] [Google Scholar]

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