Skip to main content
PMC home page
The Journal of Clinical Investigation logoLink to The Journal of Clinical Investigation
. 1965 May;44(5):703–715. doi: 10.1172/JCI105183

Characterization of Antibodies in Human Urine*

Lars A Hanson 1,†, Eng M Tan 1,‡
PMCID: PMC292547  PMID: 14276128

Full text

PDF
708

Images in this article

707Image
on p.707
707Image
on p.707
710Image
on p.710

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. BARLOW J. L., VAN VUNAKIS H., LEVINE L. Studies on the inactivation of phage by the properdin system. II. Quantitative assay of phage-neutralizing activity. J Immunol. 1958 May;80(5):349–355. [PubMed] [Google Scholar]
  2. BERGGARD I., EDELMAN G. M. Normal counterparts to Bence-Jones proteins: free L polypeptide chains of human gamma-globulin. Proc Natl Acad Sci U S A. 1963 Mar 15;49:330–337. doi: 10.1073/pnas.49.3.330. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. BERNIER G. M., PUTNAM F. W. MONOMER--DIMER FORMS OF BENCE JONES PROTEINS. Nature. 1963 Oct 19;200:223–225. doi: 10.1038/200223b0. [DOI] [PubMed] [Google Scholar]
  4. CEDERBLAD G., HANSONLA, JOHANSSON B. G. Immunological investigation of human gamma-globulin degraded by chymotrypsin. Clin Chim Acta. 1963 Jan;8:78–85. doi: 10.1016/0009-8981(63)90202-x. [DOI] [PubMed] [Google Scholar]
  5. COONS A. H., KAPLAN M. H. Localization of antigen in tissue cells; improvements in a method for the detection of antigen by means of fluorescent antibody. J Exp Med. 1950 Jan 1;91(1):1–13. doi: 10.1084/jem.91.1.1. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. CORNILLOT P., BOURRILLON R., MICHON J., GOT R. [Isolation and characterization of urinary gamma-globulins]. Biochim Biophys Acta. 1963 Apr 2;71:89–96. doi: 10.1016/0006-3002(63)90988-0. [DOI] [PubMed] [Google Scholar]
  7. DEICHER H. R., HOLMAN H. R., KUNKEL H. G. The precipitin reaction between DNA and a serum factor in systemic lupus erythematosus. J Exp Med. 1959 Jan 1;109(1):97–114. doi: 10.1084/jem.109.1.97. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. EDELMAN G. M., GALLY J. A. The nature of Bence-Jones proteins. Chemical similarities to polypetide chains of myeloma globulins and normal gamma-globulins. J Exp Med. 1962 Aug 1;116:207–227. doi: 10.1084/jem.116.2.207. [DOI] [PMC free article] [PubMed] [Google Scholar]
  9. EDELMAN G. M., HEREMANS J. F., HEREMANS M. T., KUNKEL H. G. Immunological studies of human gamma-globulin. Relation of the precipitin lines of whole gamma-globulin to those of the fragments produced by papain. J Exp Med. 1960 Jul 1;112:203–223. doi: 10.1084/jem.112.1.203. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. EDELMAN G. M., POULIK M. D. Studies on structural units of the gamma-globulins. J Exp Med. 1961 May 1;113:861–884. doi: 10.1084/jem.113.5.861. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. FLEISCHMAN J. B., PAIN R. H., PORTER R. R. Reduction of gamma-globulins. Arch Biochem Biophys. 1962 Sep;Suppl 1:174–180. [PubMed] [Google Scholar]
  12. FRANEK F., NEZLIN R. S. Recovery of antibody combining activity by interaction of different peptide chains isolated from purified horse antitoxins. Folia Microbiol (Praha) 1963 Mar;8:128–130. doi: 10.1007/BF02877236. [DOI] [PubMed] [Google Scholar]
  13. FRANKLIN E. C. Physicochemical and immunologic studies of gamma globulins of normal human urine. J Clin Invest. 1959 Dec;38:2159–2167. doi: 10.1172/JCI103995. [DOI] [PMC free article] [PubMed] [Google Scholar]
  14. GRANT G. H. The proteins of normal urine. J Clin Pathol. 1957 Nov;10(4):360–368. doi: 10.1136/jcp.10.4.360. [DOI] [PMC free article] [PubMed] [Google Scholar]
  15. HANSON L. A., BERGGARD I. An immunological comparison of immunoglobulins from human blood serum, urine and milk using diffusion-in-gel methods. Clin Chim Acta. 1962 Nov;7:828–834. doi: 10.1016/0009-8981(62)90067-0. [DOI] [PubMed] [Google Scholar]
  16. HANSON L. A., JOHANSSON B. G. Isolation of immunologically active fragments of normal human gamma-globulin after tryptic degradation. Clin Chim Acta. 1963 Jan;8:66–78. doi: 10.1016/0009-8981(63)90201-8. [DOI] [PubMed] [Google Scholar]
  17. HAUSER Elektrophoretische Untersuchungen des Urineiweisses bei akut verlaufendem Lupus erythematodes. Arch Klin Exp Dermatol. 1955;200:564–565. [PubMed] [Google Scholar]
  18. JESAITIS M. A. The inheritance of the glucose component of the phage nucleic acids. J Gen Physiol. 1961 Jan;44:585–603. doi: 10.1085/jgp.44.3.585. [DOI] [PMC free article] [PubMed] [Google Scholar]
  19. KULBERG A. Y., TARKHANOVA I. A. Isolation of a low molecular weight antibody fraction containing the antideterminant. Folia Biol (Praha) 1962 Jun;8:147–151. [PubMed] [Google Scholar]
  20. LERNER A. M., REMINGTON J. S., FINLAND M. Neutralizing antibody to polioviruses in normal human urine. J Clin Invest. 1962 Apr;41:805–815. doi: 10.1172/JCI104538. [DOI] [PMC free article] [PubMed] [Google Scholar]
  21. MERLER E., REMINGTON J. S., FINLAND M., GITLIN D. CHARACTERIZATION OF ANTIBODIES IN NORMAL HUMAN URINE. J Clin Invest. 1963 Aug;42:1340–1352. doi: 10.1172/JCI104818. [DOI] [PMC free article] [PubMed] [Google Scholar]
  22. MORSE J. H., HEREMANS J. F. Immunoelectrophoretic analysis of human insulin-binding antibody and its papain-produced fragments. J Lab Clin Med. 1962 Jun;59:891–897. [PubMed] [Google Scholar]
  23. MULLER-EBERHARD H. J. A new supporting medium for preparative electrophoresis. Scand J Clin Lab Invest. 1960;12:33–37. [PubMed] [Google Scholar]
  24. McKay E., Slater R. J. STUDIES ON HUMAN PROTEINURIA. II. SOME CHARACTERISTICS OF THE GAMMA GLOBULINS EXCRETED IN NORMAL, EXERCISE, POSTURAL, AND NEPHROTIC PROTEINURIA. J Clin Invest. 1962 Aug;41(8):1638–1652. doi: 10.1172/JCI104621. [DOI] [PMC free article] [PubMed] [Google Scholar]
  25. OSTERLAND C. K., HARBOE M., KUNKEL H. G. Anti-gamma-globulin factors in human sera revealed by enzymatic splitting of anti-Rh antibodies. Vox Sang. 1963 Mar-Apr;8:133–152. doi: 10.1111/j.1423-0410.1963.tb03290.x. [DOI] [PubMed] [Google Scholar]
  26. OUCHTERLONY O. Diffusion-in-gel methods for immunological analysis. Prog Allergy. 1958;5:1–78. [PubMed] [Google Scholar]
  27. PUTNAM F. W., MIYAKE A. Proteins in multiple myeloma. VIII. Biosynthesis of abnormal proteins. J Biol Chem. 1958 Apr;231(2):671–684. [PubMed] [Google Scholar]
  28. REMINGTON J. S., FINLAND M. Precipitating antibody in normal human urine. Proc Soc Exp Biol Med. 1961 Aug-Sep;107:765–770. doi: 10.3181/00379727-107-26748. [DOI] [PubMed] [Google Scholar]
  29. REMINGTON J. S., MERLER E., LERNER A. M., GITLIN D., FINLAND M. Antibodies of low molecular weight in normal human urine. Nature. 1962 Apr 28;194:407–408. doi: 10.1038/194407a0. [DOI] [PubMed] [Google Scholar]
  30. ROCKEY J. H., KUNKEL H. G. Unusual sedimentation and sulfhydryl sensitivity of certain isohemagglutinins and skin-sensitizing antibody. Proc Soc Exp Biol Med. 1962 May;110:101–105. doi: 10.3181/00379727-110-27437. [DOI] [PubMed] [Google Scholar]
  31. SCHERAGA H. A., RUPLEY J. A. Structure and function of ribonuclease. Adv Enzymol Relat Subj Biochem. 1962;24:161–261. doi: 10.1002/9780470124888.ch4. [DOI] [PubMed] [Google Scholar]
  32. SCHROHENLOHER R. E. The degradation of human gamma-globulin by trypsin. Arch Biochem Biophys. 1963 Jun;101:456–465. doi: 10.1016/0003-9861(63)90503-4. [DOI] [PubMed] [Google Scholar]
  33. STEVENS M. B., KNOWLES B. Significance of urinary gamma globulin in lupus nephritis. I. Electrophoretic analysis. N Engl J Med. 1962 Dec 6;267:1159–1166. doi: 10.1056/NEJM196212062672301. [DOI] [PubMed] [Google Scholar]
  34. STEVENSON G. T. Detection in normal urine of protein resembling Bence Jones protein. J Clin Invest. 1960 Jul;39:1192–1200. doi: 10.1172/JCI104134. [DOI] [PMC free article] [PubMed] [Google Scholar]
  35. STEVENSON G. T. Further studies of the gamma-related proteins of normal urine. J Clin Invest. 1962 May;41:1190–1198. doi: 10.1172/JCI104572. [DOI] [PMC free article] [PubMed] [Google Scholar]
  36. WADSWORTH C., HANSON L. A. Comparative analysis of immune electrophoretic precipitates employing a modified immune electrophoretic technique. Int Arch Allergy Appl Immunol. 1960;17:165–177. doi: 10.1159/000229122. [DOI] [PubMed] [Google Scholar]
  37. WEBB T., ROSE B., SEHON A. H. Biocolloids in normal human urine. II. Physicochemical and immunochemical characteristics. Can J Biochem Physiol. 1958 Nov;36(11):1167–1175. [PubMed] [Google Scholar]

Articles from Journal of Clinical Investigation are provided here courtesy of American Society for Clinical Investigation

RESOURCES