Skip to main content
PMC home page
The Journal of Clinical Investigation logoLink to The Journal of Clinical Investigation
. 1966 Jul;45(7):1126–1136. doi: 10.1172/JCI105419

In Vitro Studies of Human Ragweed Allergy: Changes in Cellular and Humoral Activity Associated with Specific Desensitization*

Lawrence M Lichtenstein 1,2,†, Philip S Norman 1,2,‡, Walter L Winkenwerder 1,2, Abraham G Osler 1,2,§
PMCID: PMC292785  PMID: 16695914

Full text

PDF
1136

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. ARBESMAN C. E., KANTOR S. Z., RAPP D., ROSE N. R. Immunologic studies of ragweed-sensitive patients. III. Clinical aspects: the relationship of reagin and hemagglutinating antibody titers to results of hyposensitization therapy. J Allergy. 1960 Jul-Aug;31:342–350. doi: 10.1016/0021-8707(60)90070-8. [DOI] [PubMed] [Google Scholar]
  2. CONNELL J. T., SHERMAN W. B. SKIN-SENSITIZING ANTIBODY TITER. III. RELATIONSHIP OF THE SKIN-SENSITIZING ANTIBODY TITER TO THE INTRACUTANEOUS SKIN TEST, TO THE TOLERANCE OF INJECTIONS OF ANTIGENS, AND TO THE EFFECTS OF PROLONGED TREATMENT WITH ANTIGEN. J Allergy. 1964 Mar-Apr;35:169–176. doi: 10.1016/0021-8707(64)90031-0. [DOI] [PubMed] [Google Scholar]
  3. CONNELL J. T., SHERMAN W. B. SKIN-SENSITIZING ANTIBODY. II. RELATIONSHIP OF HAY FEVER SYMPTOMS TO THE SKIN-SENSITIZING ANTIBODY TITER IN PATIENTS TREATED WITH RAGWEED EMULSION INJECTIONS, AQUEOUS RAGWEED INJECTIONS, OR NO INJECTION TREATMENT. J Allergy. 1964 Jan-Feb;35:18–26. doi: 10.1016/0021-8707(64)90045-0. [DOI] [PubMed] [Google Scholar]
  4. FEINBERG S. M., STIER R. A., GRATER W. C. A suggested quantitative evaluation of the degree of sensitivity of patients with ragweed pollinosis. J Allergy. 1952 Sep;23(5):387–394. doi: 10.1016/0021-8707(52)90001-4. [DOI] [PubMed] [Google Scholar]
  5. GORDON J., ROSE B., SEHON A. H. Detection of non-precipitating antibodies in sera of individuals allergic to ragweed pollen by an in vitro method. J Exp Med. 1958 Jul 1;108(1):37–51. doi: 10.1084/jem.108.1.37. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. JOHNSTONE D. E. Study of the role of antigen dosage in the treatment of pollenosis and pollen asthma. AMA J Dis Child. 1957 Jul;94(1):1–5. doi: 10.1001/archpedi.1957.04030020003001. [DOI] [PubMed] [Google Scholar]
  7. KING T. P., NORMAN P. S., CONNELL J. T. ISOLATION AND CHARACTERIZATION OF ALLERGENS FROM RAGWEED POLLEN. II. Biochemistry. 1964 Mar;3:458–468. doi: 10.1021/bi00891a026. [DOI] [PubMed] [Google Scholar]
  8. KING T. P., NORMAN P. S. Isolation studies of allergens from regweed pollen. Biochemistry. 1962 Jul;1:709–720. doi: 10.1021/bi00910a027. [DOI] [PubMed] [Google Scholar]
  9. LICHTENSTEIN L. M., OSLER A. G. STUDIES ON THE MECHANISMS OF HYPERSENSITIVITY PHENOMENA. IX. HISTAMINE RELEASE FROM HUMAN LEUKOCYTES BY RAGWEED POLLEN ANTIGEN. J Exp Med. 1964 Oct 1;120:507–530. doi: 10.1084/jem.120.4.507. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. Lichtenstein L. M., Osler A. G. Studies on the mechanism of hypersensitivity phenomena. XI. The effect of normal human serum on the release of histamine from human leukocytes by ragweed pollen antigen. J Immunol. 1966 Jan;96(1):159–168. [PubMed] [Google Scholar]
  11. Lichtenstein L. M., Osler A. G. Studies on the mechanisms of hypersensitivity phenomena. XII. An in vitro study of the reaction between ragweed pollen antigen, allergic human serum and ragweed-sensitive human leukocytes. J Immunol. 1966 Jan;96(1):169–179. [PubMed] [Google Scholar]
  12. NORMAN P. S., WINKENWERDER W. L. SUPPRESSION OF HAY FEVER SYMPTOMS WITH INTRANASAL DEXAMETHASONE AEROSOL. J Allergy. 1965 May-Jun;36:284–292. doi: 10.1016/0021-8707(65)90087-0. [DOI] [PubMed] [Google Scholar]
  13. SHORE P. A., BURKHALTER A., COHN V. H., Jr A method for the fluorometric assay of histamine in tissues. J Pharmacol Exp Ther. 1959 Nov;127:182–186. [PubMed] [Google Scholar]
  14. SPAIN W. C., STRAUSS M. B., NEUMANN E. In vitro release of histamine by hypersensitive (allergic) serum in contrast to immune (treated) allergic serum in antigen and normal rabbit blood mixtures. J Allergy. 1950 Jul;21(4):318–325. doi: 10.1016/0021-8707(50)90065-7. [DOI] [PubMed] [Google Scholar]
  15. TUFT L., BLUMSTEIN G. I. Pollen tolerance nasal tests in hay fever experimental and clinical observations. J Allergy. 1950 Jul;21(4):326–333. doi: 10.1016/0021-8707(50)90066-9. [DOI] [PubMed] [Google Scholar]
  16. VANARSDEL P. P., Jr, MIDDLETON E., Jr The effect of hyposensitization on the in vitro histamine release by specific antigen. J Allergy. 1961 Jul-Aug;32:348–356. doi: 10.1016/0021-8707(61)90103-4. [DOI] [PubMed] [Google Scholar]

Articles from Journal of Clinical Investigation are provided here courtesy of American Society for Clinical Investigation

RESOURCES