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. 1966 Aug;45(8):1302–1316. doi: 10.1172/JCI105437

Distribution, conjugation, and excretion of labeled aldosterone in congestive heart failure and in controls with normal circulation: development and testing of a model with an analog computer.

R A Cheville, J A Luetscher, E W Hancock, A J Dowdy, G W Nokes
PMCID: PMC292806  PMID: 5923702

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. AYERS C. R., DAVIS J. O., LIEBERMAN F., CARPENTER C. C., BERMAN M. The effects of chronic hepatic venous congestion on the metabolism of d,1-aldosterone and d-aldosterone. J Clin Invest. 1962 Apr;41:884–895. doi: 10.1172/JCI104545. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. BERMAN M. The formulation and testing of models. Ann N Y Acad Sci. 1963 May 10;108:182–194. doi: 10.1111/j.1749-6632.1963.tb13373.x. [DOI] [PubMed] [Google Scholar]
  3. Bledsoe T., Liddle G. W., Riondel A., Island D. P., Bloomfield D., Sinclair-Smith B. Comparative fates of intravenously and orally administered aldosterone: evidence for extrahepatic formation of acid-hydrolyzable conjugate in man. J Clin Invest. 1966 Feb;45(2):264–269. doi: 10.1172/JCI105339. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. CAMARGO C. A., DOWDY A. J., HANCOCK E. W., LUETSCHER J. A. DECREASED PLASMA CLEARANCE AND HEPATIC EXTRACTION OF ALDOSTERONE IN PATIENTS WITH HEART FAILURE. J Clin Invest. 1965 Mar;44:356–365. doi: 10.1172/JCI105149. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. COPPAGE W. S., Jr, ISLAND D. P., COONER A. E., LIDDLE G. W. The metabolism of aldosterone in normal subjects and in patients with hepatic cirrhosis. J Clin Invest. 1962 Aug;41:1672–1680. doi: 10.1172/JCI104624. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. DAVIS J. O., OLICHNEY M. J., BROWN T. C., BINNION P. F. METABOLISM OF ALDOSTERONE IN SEVERAL EXPERIMENTAL SITUATIONS WITH ALTERED ALDOSTERONE SECRETION. J Clin Invest. 1965 Sep;44:1433–1441. doi: 10.1172/JCI105249. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. GFELLER J., SIEGENTHALER W. DIE RENALE CLEARANCE DES ALDOSTERONS UND SEINER HAUPTMETABOLITE BEIM MENSCHEN. Acta Endocrinol (Copenh) 1965 Aug;49:510–524. [PubMed] [Google Scholar]
  8. LUETSCHER J. A., CAMARGO C. A., HANCOCK E. W., DOWDY A. J., NOKES G. W. OBSERVATIONS OF ALDOSTERONE METABOLISM IN CONGESTIVE HEART FAILURE. Trans Assoc Am Physicians. 1964;77:224–231. [PubMed] [Google Scholar]
  9. LUETSCHER J. A., HANCOCK E. W., CAMARGO C. A., DOWDY A. J., NOKES G. W. CONJUGATION OF 1,2-3H-ALDOSTERONE IN HUMAN LIVER AND KIDNEYS AND RENAL EXTRACTION OF ALDOSTERONE AND LABELED CONJUGATES FROM BLOOD PLASMA. J Clin Endocrinol Metab. 1965 May;25:628–638. doi: 10.1210/jcem-25-5-628. [DOI] [PubMed] [Google Scholar]
  10. MEYER C. J., LAYNE D. S., TAIT J. F., PINCUS G. The binding of aldosterone to plasma proteins in normal, pregnant, and steroid-treated women. J Clin Invest. 1961 Sep;40:1663–1671. doi: 10.1172/JCI104389. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. SANDOR T., LANTHIER A. The metabolism of aldosterone. II. Acta Endocrinol (Copenh) 1962 Jan;39:87–102. doi: 10.1530/acta.0.0390087. [DOI] [PubMed] [Google Scholar]
  12. SULYA L. L., MCCAA C. S., READ V. H., BOMER D. UPTAKE OF TRITIATED ALDOSTERONE BY RAT TISSUES. Nature. 1963 Nov 23;200:788–789. doi: 10.1038/200788b0. [DOI] [PubMed] [Google Scholar]
  13. TAIT J. F., LITTLE B., TAIT S. A., FLOOD C., BOUGAS J. SPLANCHNIC EXTRACTION AND CLEARANCE OF ALDOSTERONE IN SUBJECTS WITH MINIMAL AND MARKED CARDIAC DYSFUNCTION. J Clin Endocrinol Metab. 1965 Feb;25:219–228. doi: 10.1210/jcem-25-2-219. [DOI] [PubMed] [Google Scholar]
  14. TAIT J. F., LITTLE B., TAIT S. A., FLOOD C. The metabolic clearance rate of aldosterone in pregnant and nonpregnant subjects estimated by both single-injection and constant-infusion methods. J Clin Invest. 1962 Dec;41:2093–2100. doi: 10.1172/JCI104667. [DOI] [PMC free article] [PubMed] [Google Scholar]
  15. TAIT J. F., TAIT S. A., LITTLE B., LAUMAS K. R. The disappearance of 7-H-3-d-aldosterone in the plasma of normal subjects. J Clin Invest. 1961 Jan;40:72–80. doi: 10.1172/JCI104239. [DOI] [PMC free article] [PubMed] [Google Scholar]
  16. UNDERWOOD R. H., TAIT J. F. PURIFICATION, PARTIAL CHARACTERIZATION AND METABOLISM OF AN ACID LABILE CONJUGATE OF ALDOSTERONE. J Clin Endocrinol Metab. 1964 Nov;24:1110–1124. doi: 10.1210/jcem-24-11-1110. [DOI] [PubMed] [Google Scholar]

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