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. 1959 Apr;38(4):652–658. doi: 10.1172/JCI103843

THE RENAL EXCRETION OF HEMOGLOBIN: REGULATORY MECHANISMS AND THE DIFFERENTIAL EXCRETION OF FREE AND PROTEIN-BOUND HEMOGLOBIN*,

Willoughby Lathem 1
PMCID: PMC293204  PMID: 13641416

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. ALLISON A. C., REES W. A. The binding of haemoglobin by plasma proteins (haptoglobins); its bearing on the renal threshold for haemoglobin and the aetiology of haemoglobinuria. Br Med J. 1957 Nov 16;2(5054):1137–1143. doi: 10.1136/bmj.2.5054.1137. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. CROSBY W. H., DAMESHEK W. The significance of hemoglobinemia and associated hemosiderinuria, with particular reference to various types of hemolytic anemia. J Lab Clin Med. 1951 Dec;38(6):829–841. [PubMed] [Google Scholar]
  3. FINCH C. A., HEGSTED M., KINNEY T. D., THOMAS E. D., RATH C. E., HASKINS D., FINCH S., FLUHARTY R. G. Iron metabolism; the pathophysiology of iron storage. Blood. 1950 Nov;5(11):983–1008. [PubMed] [Google Scholar]
  4. GOODWIN W. E., ALSTON E. F., SEMANS J. H. Hematuria and sickle cell disease; unexplained, gross unilateral, renal hematuria in Negroes, coincident with the blood sickling trait. J Urol. 1950 Jan;63(1):79-96, illust. doi: 10.1016/S0022-5347(17)68735-4. [DOI] [PubMed] [Google Scholar]
  5. JAYLE M. F., CONAS G. Propriétés et constitution chimique de l'haptoglobine sérique. Bull Soc Chim Biol (Paris) 1952 Jan-Feb;34(1-2):65–76. [PubMed] [Google Scholar]
  6. LATHEM W., WORLEY W. E. The distribution of extracorpuscular hemoglobin in circulating plasma. J Clin Invest. 1959 Mar;38(3):474–483. doi: 10.1172/JCI103823. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. LAURELL C. B., NYMAN M. Studies on the serum haptoglobin level in hemoglobinemia and its influence on renal excretion of hemoglobin. Blood. 1957 Jun;12(6):493–506. [PubMed] [Google Scholar]
  8. MILLER J. H., McDONALD R. K. The effect of hemoglobin on renal function in the human. J Clin Invest. 1951 Oct;30(10):1033–1040. doi: 10.1172/JCI102522. [DOI] [PMC free article] [PubMed] [Google Scholar]
  9. McDONALD R. K., MILLER J. H., ROACH E. B. Human glomerular permeability and tubular recovery values for hemoglobin. J Clin Invest. 1951 Oct;30(10):1041–1045. doi: 10.1172/JCI102523. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. OLIVER J., MACDOWELL M., LEE Y. C. Cellular mechanisms of protein metabolism in the nephron. I. The structural aspects of proteinuria; tubular absorption, droplet formation, and the disposal of proteins. J Exp Med. 1954 Jun 1;99(6):589–604. doi: 10.1084/jem.99.6.589. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. PAPPENHEIMER J. R. Passage of molecules through capillary wals. Physiol Rev. 1953 Jul;33(3):387–423. doi: 10.1152/physrev.1953.33.3.387. [DOI] [PubMed] [Google Scholar]

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