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. 1959 Jul;38(7):1096–1110. doi: 10.1172/JCI103886

THE MAINTENANCE OF A SUSTAINED THROMBOLYTIC STATE IN MAN. I. INDUCTION AND EFFECTS*

Anthony P Fletcher 1, Norma Alkjaersig 1, Sol Sherry 1
PMCID: PMC293257  PMID: 13664785

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. ALKJAERSIG N., FLETCHER A. P., SHERRY S. The activation of human plasminogen. I. Spontaneous activation in glycerol. J Biol Chem. 1958 Jul;233(1):81–85. [PubMed] [Google Scholar]
  2. ALKJAERSIG N., FLETCHER A. P., SHERRY S. The mechanism of clot dissolution by plasmin. J Clin Invest. 1959 Jul;38(7):1086–1095. doi: 10.1172/JCI103885. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. AMBRUS J. L., AMBRUS C. M., BACK N., SOKAL J. E., COLLINS G. L. Clinical and experimental studies on fibrinolytic enzymes. Ann N Y Acad Sci. 1957 Aug 30;68(1):97–137. doi: 10.1111/j.1749-6632.1957.tb42616.x. [DOI] [PubMed] [Google Scholar]
  4. BACH N., AMBRUS J. L., SIMPSON C. L., SHULMAN S. Study on the effect of streptokinase-activated plasmin (fibrinolysin) on clots in various stages of organization. J Clin Invest. 1958 Jun;37(6):864–871. doi: 10.1172/JCI103677. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. CARTER J. R., WARNER E. D. Correction by defects in clotting accelerator activity by administration of methionine and vitamin K and of a new sulfhydryl-substituted methylnaphthoquinone, vitamin K-S(II). J Clin Invest. 1958 Jan;37(1):70–86. doi: 10.1172/JCI103587. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. CLIFFTON E. E. The use of plasmin in humans. Ann N Y Acad Sci. 1957 Aug 30;68(1):209–229. doi: 10.1111/j.1749-6632.1957.tb42627.x. [DOI] [PubMed] [Google Scholar]
  7. DEUTSCH E., SCHADEN W. Zur Reingung und Charakterisierung des VII. Blutgerinnungsfaktors. Biochem Z. 1953;324(4):266–279. [PubMed] [Google Scholar]
  8. FLETCHER A. P., ALKJAERSIG N., SHERRY S. The clearance of heterologous protein from the circulation of normal and immunized man. J Clin Invest. 1958 Sep;37(9):1306–1315. doi: 10.1172/JCI103719. [DOI] [PMC free article] [PubMed] [Google Scholar]
  9. FLETCHER A. P., JOHNSON A. J. Methods employed for purification of streptokinase. Proc Soc Exp Biol Med. 1957 Jan;94(1):233–236. doi: 10.3181/00379727-94-22909. [DOI] [PubMed] [Google Scholar]
  10. FLETCHER A. P., SHERRY S., ALKJAERSIG N., SMYRNIOTIS F. E., JICK S. The maintenance of a sustained thrombolytic state in man. II. Clinical observations on patients with myocardial infarction and other thromboembolic disorders. J Clin Invest. 1959 Jul;38(7):1111–1119. doi: 10.1172/JCI103887. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. JOHNSON A. J., FLETCHER A. P., MCCARTY W. R., TILLETT W. S. Effects in patients of intravenous infusions of purified streptokinase preparations. Proc Soc Exp Biol Med. 1957 Feb;94(2):254–258. doi: 10.3181/00379727-94-22913. [DOI] [PubMed] [Google Scholar]
  12. JOHNSON A. J., FLETCHER A. P., McCARTY W. R., TILLETT W. S. The intravascular use of streptokinase. Ann N Y Acad Sci. 1957 Aug 30;68(1):201–208. doi: 10.1111/j.1749-6632.1957.tb42626.x. [DOI] [PubMed] [Google Scholar]
  13. JOHNSON A. J., TILLETT W. S. The lysis in rabbits of intravascular blood clots by the streptococcal fibrinolytic system (streptokinase). J Exp Med. 1952 May 1;95(5):449–464. doi: 10.1084/jem.95.5.449. [DOI] [PMC free article] [PubMed] [Google Scholar]
  14. KARMEN A., WROBLEWSKI F., LADUE J. S. Transaminase activity in human blood. J Clin Invest. 1955 Jan;34(1):126–131. doi: 10.1172/JCI103055. [DOI] [PMC free article] [PubMed] [Google Scholar]
  15. KELLNER A., ROBERTSON T. Selective necrosis of cardiac and skeletal muscle induced experimentally by means of proteolytic enzyme solutions given intravenously. J Exp Med. 1954 Apr 1;99(4):387–404. doi: 10.1084/jem.99.4.387. [DOI] [PMC free article] [PubMed] [Google Scholar]
  16. LOELIGER A., HERS J. F. Chronic antithrombinaemia (Antithrombin V) with Haemorrhagic diathesis in a case of rheumatoid arthritis with hypergammaglobulinaemia). Thromb Diath Haemorrh. 1957 Dec 15;1(3-4):499–528. [PubMed] [Google Scholar]
  17. MULLERTZ S. Fibrinolytic activity of human blood after death. Acta Physiol Scand. 1952;27(2-3):265–271. doi: 10.1111/j.1748-1716.1953.tb00942.x. [DOI] [PubMed] [Google Scholar]
  18. MULLERTZ S. Formation and properties of the activator of plasminogen and of human and bovine plasmin. Biochem J. 1955 Nov;61(3):424–434. doi: 10.1042/bj0610424. [DOI] [PMC free article] [PubMed] [Google Scholar]
  19. SEEGERS W. H., JOHNSON J. F., FELL C. An antithrombin reaction to prothrombin activation. Am J Physiol. 1954 Jan;176(1):97–103. doi: 10.1152/ajplegacy.1953.176.1.97. [DOI] [PubMed] [Google Scholar]
  20. SHERRY S., ALKJAERSIG N. Biochemical experimental, and clinical studies of proteolytic enzymes with particular reference to the fibrinolytic enzyme of human plasma. Ann N Y Acad Sci. 1957 Aug 30;68(1):52–66. doi: 10.1111/j.1749-6632.1957.tb42612.x. [DOI] [PubMed] [Google Scholar]
  21. SHERRY S., ALKJAERSIG N. Studies on the fibrinolytic enzyme of human plasma. Thromb Diath Haemorrh. 1957 Aug 15;1(2):264–288. [PubMed] [Google Scholar]
  22. SHERRY S., LINDEMEYER R. I., FLETCHER A. P., ALKJAERSIG N. Studies on enhanced fibrinolytic activity in man. J Clin Invest. 1959 May;38(5):810–822. doi: 10.1172/JCI103863. [DOI] [PMC free article] [PubMed] [Google Scholar]
  23. SHERRY S., TITCHENER A., GOTTESMAN L., WASSERMAN P., TROLL W. The enzymatic dissolution of experimental arterial thrombi in the dog by trypsin, chymotrypsin and plasminogen activators. J Clin Invest. 1954 Oct;33(10):1303–1313. doi: 10.1172/JCI103006. [DOI] [PMC free article] [PubMed] [Google Scholar]
  24. TILLETT W. S., JOHNSON A. J., McCARTY W. R. The intravenous infusion of the streptococcal fibrinolytic principle (streptokinase) into patients. J Clin Invest. 1955 Feb;34(2):169–185. doi: 10.1172/JCI103071. [DOI] [PMC free article] [PubMed] [Google Scholar]
  25. TROLL W., SHERRY S. The activation of human plasminogen by streptokinase. J Biol Chem. 1955 Apr;213(2):881–891. [PubMed] [Google Scholar]
  26. VON KAULLA K. N., SWAN H. Clotting deviations in man during cardiac bypass: fibrinolysis and circulating anticoagulant. J Thorac Surg. 1958 Oct;36(4):519–530. [PubMed] [Google Scholar]

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