Skip to main content
PMC home page
The Journal of Clinical Investigation logoLink to The Journal of Clinical Investigation
. 1959 Dec;38(12):2176–2188. doi: 10.1172/JCI103997

INTERRELATIONS OF PLASMA POTASSIUM CONCENTRATION, PLASMA SODIUM CONCENTRATION, ARTERIAL pH AND TOTAL EXCHANGEABLE POTASSIUM*

J Leibman 1,†, I S Edelman 1,‡
PMCID: PMC293309  PMID: 14415423

Full text

PDF
2176

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. AGNA J. W., KNOWLES H. C., Jr Further studies on the erythrocyte concentration of potassium in conditions of hyponatremia and hypernatremia. J Lab Clin Med. 1958 Mar;51(3):359–363. [PubMed] [Google Scholar]
  2. ANDERSON H. M., LARAGH J. H. Renal excretion of potassium in normal and sodium depleted dogs. J Clin Invest. 1958 Mar;37(3):323–331. doi: 10.1172/JCI103612. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. BERLINER R. W., KENNEDY T. J., Jr, ORLOFF J. Relationship between acidification of the urine and potassium metabolism; effect of carbonic anhydrase inhibition on potassium excretion. Am J Med. 1951 Sep;11(3):274–282. doi: 10.1016/0002-9343(51)90165-9. [DOI] [PubMed] [Google Scholar]
  4. BIRKENFELD L. W., LEIBMAN J., O'MEARA M. P., EDELMAN I. S. Total exchangeable sodium, total exchangeable potassium, and total body water in edematous patients with cirrhosis of the liver and congestive heart failure. J Clin Invest. 1958 May;37(5):687–698. doi: 10.1172/JCI103655. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. BURNELL J. M., SCRIBNER B. H., UYENO B. T., VILLAMIL M. F. The effect in humans of extracellular pH change on the relationship between serum potassium concentration and intracellular potassium. J Clin Invest. 1956 Sep;35(9):935–939. doi: 10.1172/JCI103352. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. CORSA L., Jr, OLNEY J. M., Jr, STEENBURG R. W., BALL M. R., MOORE F. D. The measurement of exchangeable potassium in man by isotope dilution. J Clin Invest. 1950 Oct;29(10):1280–1295. doi: 10.1172/JCI102365. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. EDELMAN I. S., LEIBMAN J. Anatomy of body water and electrolytes. Am J Med. 1959 Aug;27:256–277. doi: 10.1016/0002-9343(59)90346-8. [DOI] [PubMed] [Google Scholar]
  8. EDELMAN I. S., LEIBMAN J., O'MEARA M. P., BIRKENFELD L. W. Interrelations between serum sodium concentration, serum osmolarity and total exchangeable sodium, total exchangeable potassium and total body water. J Clin Invest. 1958 Sep;37(9):1236–1256. doi: 10.1172/JCI103712. [DOI] [PMC free article] [PubMed] [Google Scholar]
  9. ELKINTON J. R., SINGER R. B., BARKER E. S., CLARK J. K. Effects in man of acute experimental respiratory alkalosis and acidosis on ionic transfers in the total body fluids. J Clin Invest. 1955 Nov;34(11):1671–1690. doi: 10.1172/JCI103221. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. FENN W. O., ASANO T. Effects of carbon dioxide inhalation on potassium liberation from the liver. Am J Physiol. 1956 Jun;185(3):567–576. doi: 10.1152/ajplegacy.1956.185.3.567. [DOI] [PubMed] [Google Scholar]
  11. GIEBISCH G., BERGER L., PITTS R. F. The extrarenal response to acute acid-base disturbances of respiratory origin. J Clin Invest. 1955 Feb;34(2):231–245. doi: 10.1172/JCI103076. [DOI] [PMC free article] [PubMed] [Google Scholar]
  12. HICKAM J. B., WILSON W. P., FRAYSER R. Observations on the early elevation of serum potassium during respiratory alkalosis. J Clin Invest. 1956 Jun;35(6):601–606. doi: 10.1172/JCI103314. [DOI] [PMC free article] [PubMed] [Google Scholar]
  13. KEATING R. E., WEICHSELBAUM T. E., ALANIS M., MARGRAF H. W., ELMAN R. The movement of potassium during experimental acidosis and alkalosis in the nephrectomized dog. Surg Gynecol Obstet. 1953 Mar;96(3):323–330. [PubMed] [Google Scholar]
  14. LANGHAM W. H., EVERSOLE W. J., HAYES F. N., TRUJILLO T. T. Assay of tritium activity in body fluids with use of a liquid scintillation system. J Lab Clin Med. 1956 May;47(5):819–825. [PubMed] [Google Scholar]
  15. LARAGH J. H., CAPECI N. E. Effect of administration of potassium chloride on serum sodium and potassium concentration. Am J Physiol. 1955 Mar;180(3):539–544. doi: 10.1152/ajplegacy.1955.180.3.539. [DOI] [PubMed] [Google Scholar]
  16. MOKOTOFF R., ROSS G., LEITER L. The electrolyte content of skeletal muscle in congestive heart failure; a comparison of results with inulin and chloride as reference standards for extracellular water. J Clin Invest. 1952 Mar;31(3):291–299. doi: 10.1172/JCI102605. [DOI] [PMC free article] [PubMed] [Google Scholar]
  17. MOORE F. D., BOLING E. A., DITMORE H. B., Jr, SICULAR A., TETERICK J. E., ELLISON A. E., HOYE S. J., BALL M. R. Body sodium and potassium. V. The relationship of alkalosis, potassium deficiency and surgical stress to acute hypokalemia in man; experiments and review of the literature. Metabolism. 1955 Sep;4(5):379–402. [PubMed] [Google Scholar]
  18. MOORE F. D. Common patterns of water and electrolyte change in injury, surgery and disease. N Engl J Med. 1958 Feb 6;258(6):277–contd. doi: 10.1056/NEJM195802062580606. [DOI] [PubMed] [Google Scholar]
  19. MOORE F. D., EDELMAN I. S., OLNEY J. M., JAMES A. H., BROOKS L., WILSON G. M. Body sodium and potassium. III. Interrelated trends in alimentary, renal and cardiovascular disease; lack of correlation between body stores and plasma concentration. Metabolism. 1954 Jul;3(4):334–350. [PubMed] [Google Scholar]
  20. MUIRHEAD E. E., GOTH A., JONES F. Sodium and potassium exchanges associated with nor-epinephrine infusions. Am J Physiol. 1954 Oct;179(1):1–4. doi: 10.1152/ajplegacy.1954.179.1.1. [DOI] [PubMed] [Google Scholar]
  21. MULDOWNEY F. P., CROOKS J., BLUHM M. M. The relationship of total exchangeable potassium and chloride to lean body mass, red cell mass and creatinine excretion in man. J Clin Invest. 1957 Sep;36(9):1375–1381. doi: 10.1172/JCI103537. [DOI] [PMC free article] [PubMed] [Google Scholar]
  22. Mudge G. H., Vislocky K. ELECTROLYTE CHANGES IN HUMAN STRIATED MUSCLE IN ACIDOSIS AND ALKALOSIS. J Clin Invest. 1949 May;28(3):482–486. doi: 10.1172/JCI102094. [DOI] [PMC free article] [PubMed] [Google Scholar]
  23. O'BRIEN G. S., MURPHY Q. R., Jr, MEEK W. J. The effect of sympathomimetic amines on arterial plasma potassium and cardiac rhythm in anesthetized dogs. J Pharmacol Exp Ther. 1953 Dec;109(4):453–460. [PubMed] [Google Scholar]
  24. O'MEARA M. P., BIRKENFELD L. W., GOTCH F. A., EDELMAN I. S. The equilibration of radiosodium (Na24), radiopotassium (K42), and deuterium oxide (D2O) in hydropic human subjects. J Clin Invest. 1957 Jun;36(6 Pt 1):784–792. doi: 10.1172/JCI103483. [DOI] [PMC free article] [PubMed] [Google Scholar]
  25. ORLOFF J., WALSER M., KENNEDY T. J., Jr, BARTTER F. C. Hyponatremia. Circulation. 1959 Feb;19(2):284–299. doi: 10.1161/01.cir.19.2.284. [DOI] [PubMed] [Google Scholar]
  26. RIECKER G., VON BUBNOFF M. Uber den intracellulären Wasser- und Elektrolytstoffwechsel; Untersuchungen an Erythrocyten. II. Odemkrankheiten. Klin Wochenschr. 1958 Jun 15;36(12):556–560. doi: 10.1007/BF01497865. [DOI] [PubMed] [Google Scholar]
  27. SANDERSON P. H. Potentiometric determination of chloride in biological fluids. Biochem J. 1952 Nov;52(3):502–505. doi: 10.1042/bj0520502. [DOI] [PMC free article] [PubMed] [Google Scholar]
  28. SCHLOERB P. R., FRIIS-HANSEN B. J., EDELMAN I. S., SOLOMON A. K., MOORE F. D. The measurement of total body water in the human subject by deuterium oxide dilution; with a consideration of the dynamics of deuterium distribution. J Clin Invest. 1950 Oct;29(10):1296–1310. doi: 10.1172/JCI102366. [DOI] [PMC free article] [PubMed] [Google Scholar]
  29. SCRIBNER B. H., BURNELL J. M. Interpretation of the serum potassium concentration. Metabolism. 1956 Jul;5(4):468–479. [PubMed] [Google Scholar]
  30. SCRIBNER B. H., FREMONT-SMITH K., BURNELL J. M. The effect of acute respiratory acidosis on the internal equilibrium of potassium. J Clin Invest. 1955 Aug;34(8):1276–1285. doi: 10.1172/JCI103174. [DOI] [PMC free article] [PubMed] [Google Scholar]
  31. SHEPPARD C. W., MARTIN W. R., BEYL G. Cation exchange between cells and plasma of mammalian blood. II. Sodium and potassium exchange in the sheep, dog, cow, and man and the effect of varying the plasma potassium concentration. J Gen Physiol. 1951 Mar 20;34(4):411–429. doi: 10.1085/jgp.34.4.411. [DOI] [PMC free article] [PubMed] [Google Scholar]
  32. STANBURY S. W., THOMSON A. E. The renal response to respiratory alkalosis. Clin Sci. 1952 Nov;11(4):357–374. [PubMed] [Google Scholar]
  33. SWAN R. C., AXELROD D. R., SEIP M., PITTS R. F. Distribution of sodium bicarbonate infused into nephrectomized dogs. J Clin Invest. 1955 Dec;34(12):1795–1801. doi: 10.1172/JCI103234. [DOI] [PMC free article] [PubMed] [Google Scholar]
  34. SWAN R. C., PITTS R. F. Neutralization of infused acid by nephrectomized dogs. J Clin Invest. 1955 Feb;34(2):205–212. doi: 10.1172/JCI103073. [DOI] [PMC free article] [PubMed] [Google Scholar]
  35. TALSO P. J., SPAFFORD N., BLAW M. The metabolism of water and electrolytes in congestive heart failure. II. The distribution of water and electrolytes in skeletal muscle in edematous patients with congestive heart failure before and after treatment. J Lab Clin Med. 1953 Mar;41(3):405–415. [PubMed] [Google Scholar]
  36. TOBIN R. B. Plasma, extracellular and muscle electrolyte responses to acute metabolic acidosis. Am J Physiol. 1956 Jul;186(1):131–138. doi: 10.1152/ajplegacy.1956.186.1.131. [DOI] [PubMed] [Google Scholar]
  37. TOBIN R. B. Varying role of extracellular electrolytes in metabolic acidosis and alkalosis. Am J Physiol. 1958 Dec;195(3):685–692. doi: 10.1152/ajplegacy.1958.195.3.685. [DOI] [PubMed] [Google Scholar]
  38. YOUNG W. G., Jr, SEALY W. C., HARRIS J. S. The role of intracellular and extracellular electrolytes in the cardiac arrhythmias produced by prolonged hypercapnia. Surgery. 1954 Sep;36(3):636–649. [PubMed] [Google Scholar]

Articles from Journal of Clinical Investigation are provided here courtesy of American Society for Clinical Investigation

RESOURCES