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. 1987 Jul 10;15(13):5433–5442. doi: 10.1093/nar/15.13.5433

The SV40 termination region exhibits an altered helical DNA conformation.

L G Poljak, J D Gralla
PMCID: PMC305970  PMID: 3037492

Abstract

The DNA structure of a fragment containing the SV40 termination sequences was examined using gel mobility assays. The region is shown to contain a DNA bend as evidenced by an abnormal mobility that is progressively accentuated as the temperature is lowered. This represents the strongest example of DNA bending among the collection of SV40 fragments studied. The same fragment was shown previously to uniquely support hyper-stable nucleosome formation in vitro, suggesting a possible relationship between DNA bending and nucleosome stability.

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Selected References

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