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. 1993 Sep 11;21(18):4369–4371. doi: 10.1093/nar/21.18.4369

dHMG-Z, a second HMG-1-related protein in Drosophila melanogaster.

S S Ner 1, M E Churchill 1, M A Searles 1, A A Travers 1
PMCID: PMC310074  PMID: 8414994

Abstract

We report the identification of dHMG-Z, a gene related to dHMG-D and encoding a second invertebrate homologue of HMG 1 protein. The encoded proteins is 65% identical to dHMG-D protein, and also contains a single HMG-box as the DNA recognition motif. Analogous to dHMG-D, two transcripts are observed for dHMG-Z which are differentially regulated, and are the product of zygotic transcription unlike the dHMG-D transcripts which arise from both maternal and zygotic transcription. The genes for dHMG-D and dHMG-Z are located on adjacent loci in the genome and each contains two introns. The position of the second intron in the coding region is conserved between the two genes suggesting a common origin via gene duplication.

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Selected References

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