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. 1989 Aug;57(8):2574–2579. doi: 10.1128/iai.57.8.2574-2579.1989

In vitro adherence of type 1-fimbriated uropathogenic Escherichia coli to human ureteral mucosa.

K Fujita 1, T Yamamoto 1, T Yokota 1, R Kitagawa 1
PMCID: PMC313490  PMID: 2568346

Abstract

Type 1-fimbriated Escherichia coli isolated from patients with urinary tract infections adhered in vitro to the epithelial cell surface of an excised human ureter. The bacteria also adhered to a mucous coating and to Formalin-fixed human ureteral mucosa. D-Mannose strongly inhibited such adherence. The bacteria in their nonfimbriated phase lacked the ability to adhere. We concluded that type 1 fimbriae play a role, at least in part, in upper urinary tract infections in humans.

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Selected References

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