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. 1966 May;91(5):1819–1826. doi: 10.1128/jb.91.5.1819-1826.1966

Comparison of the Tryptophan Synthetase α Subunits of Several Species of Enterobacteriaceae

T E Creighton 1,2, D R Helinski 1,2,1, R L Somerville 1,2, C Yanofsky 1,2
PMCID: PMC316128  PMID: 5327908

Abstract

Creighton, T. E. (Stanford University, Stanford), D. R. Helinski, R. L. Somerville, and C. Yanofsky. Comparison of the tryptophan synthetase α subunits of several species of Enterobacteriaceae. J. Bacteriol. 91:1819–1826. 1966.—The tryptophan synthetase α subunits of Escherichia coli K-12, E. coli B, Shigella dysenteriae, Salmonella typhimurium, and Aerobacter aerogenes have been purified and their structures compared. Each of these α subunits exhibits a sedimentation coefficient of about 2.7S. Peptide patterns of trypsin plus chymotrypsin digests of the α subunits have indicated that all of the α subunits have peptide regions in common. The patterns of E. coli K-12, E. coli B, and S. dysenteriae α subunits appear to be nearly identical, whereas the α subunits from S. typhimurium and A. aerogenes differ from those of E. coli and from each other. It has also been shown that the E. coli structural gene for the α subunit is translated identically in E. coli and S. typhimurium.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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