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. 1989 Mar 25;17(6):2159–2180. doi: 10.1093/nar/17.6.2159

The 5' splice site: phylogenetic evolution and variable geometry of association with U1RNA.

M Jacob 1, H Gallinaro 1
PMCID: PMC317586  PMID: 2704616

Abstract

The 5' splice site sequences of 3294 introns from various organisms (1-672) were analyzed in order to determine the rules governing evolution of this sequence, which may shed light on the mechanism of cleavage at the exon-intron junction. The data indicate that, currently, in all organisms, a common sequence 1GUAAG6U and its derivatives are used as well as an additional sequence and its derivatives, which differ in metazoa (G/1GUgAG6U), lower eucaryotes (1GUAxG6U) and higher plants (AG/1GU3A). They all partly resemble the prototype sequence AG/1GUAAG6U whose 8 contigous nucleotides are complementary to the nucleotides 4-11 of U1RNA, which are perfectly conserved in the course of phylogenetic evolution. Detailed examination of the data shows that U1RNA can recognize different parts of 5' splice sites. As a rule, either prototype nucleotides at position -2 and -1 or at positions 4, 5 or 6 or at positions 3-4 are dispensable provided that the stability of the U1RNA-5' splice site hybrid is conserved. On the basis of frequency of sequences, the optimal size of the hybridizable region is 5-7 nucleotides. Thus, the cleavage at the exon-intron junction seems to imply, first, that the 5' splice site is recognized by U1RNA according to a "variable geometry" program; second, that the precise cleavage site is determined by the conserved sequence of U1RNA since it occurs exactly opposite to the junction between nucleotides C9 and C10 of U1RNA. The variable geometry of the U1RNA-5' splice site association provides flexibility to the system and allows diversification in the course of phylogenetic evolution.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Adra C. N., Boer P. H., McBurney M. W. Cloning and expression of the mouse pgk-1 gene and the nucleotide sequence of its promoter. Gene. 1987;60(1):65–74. doi: 10.1016/0378-1119(87)90214-9. [DOI] [PubMed] [Google Scholar]
  2. Aguadé M. Nucleotide sequence comparison of the rp49 gene region between Drosophila subobscura and D. melanogaster. Mol Biol Evol. 1988 Jul;5(4):433–441. doi: 10.1093/oxfordjournals.molbev.a040502. [DOI] [PubMed] [Google Scholar]
  3. Ahearn J. M., Jr, Bartolomei M. S., West M. L., Cisek L. J., Corden J. L. Cloning and sequence analysis of the mouse genomic locus encoding the largest subunit of RNA polymerase II. J Biol Chem. 1987 Aug 5;262(22):10695–10705. [PubMed] [Google Scholar]
  4. Aho S., Tate V., Boedtker H. Location of the 11 bp exon in the chicken pro alpha 2(I) collagen gene. Nucleic Acids Res. 1984 Aug 10;12(15):6117–6125. doi: 10.1093/nar/12.15.6117. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Allard A., Wadell G. Physical organization of the enteric adenovirus type 41 early region 1A. Virology. 1988 May;164(1):220–229. doi: 10.1016/0042-6822(88)90639-3. [DOI] [PubMed] [Google Scholar]
  6. Allen R. D., Cohen E. A., Vonder Haar R. A., Adams C. A., Ma D. P., Nessler C. L., Thomas T. L. Sequence and expression of a gene encoding an albumin storage protein in sunflower. Mol Gen Genet. 1987 Dec;210(2):211–218. doi: 10.1007/BF00325686. [DOI] [PubMed] [Google Scholar]
  7. Amara S. G., Evans R. M., Rosenfeld M. G. Calcitonin/calcitonin gene-related peptide transcription unit: tissue-specific expression involves selective use of alternative polyadenylation sites. Mol Cell Biol. 1984 Oct;4(10):2151–2160. doi: 10.1128/mcb.4.10.2151. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. Ann D. K., Carlson D. M. The structure and organization of a proline-rich protein gene of a mouse multigene family. J Biol Chem. 1985 Dec 15;260(29):15863–15872. [PubMed] [Google Scholar]
  9. Ann D. K., Gadbois D., Carlson D. M. Structure, organization, and regulation of a hamster proline-rich protein gene. A multigene family. J Biol Chem. 1987 Mar 25;262(9):3958–3963. [PubMed] [Google Scholar]
  10. Argentin S., Nemer M., Drouin J., Scott G. K., Kennedy B. P., Davies P. L. The gene for rat atrial natriuretic factor. J Biol Chem. 1985 Apr 25;260(8):4568–4571. [PubMed] [Google Scholar]
  11. Arnold B., Burgert H. G., Archibald A. L., Kvist S. Complete nucleotide sequence of the murine H-2Kk gene. Comparison of three H-2K locus alleles. Nucleic Acids Res. 1984 Dec 21;12(24):9473–9487. doi: 10.1093/nar/12.24.9473. [DOI] [PMC free article] [PubMed] [Google Scholar]
  12. Arpaia E., Dumbrille-Ross A., Maler T., Neote K., Tropak M., Troxel C., Stirling J. L., Pitts J. S., Bapat B., Lamhonwah A. M. Identification of an altered splice site in Ashkenazi Tay-Sachs disease. Nature. 1988 May 5;333(6168):85–86. doi: 10.1038/333085a0. [DOI] [PubMed] [Google Scholar]
  13. Bader B. L., Magin T. M., Hatzfeld M., Franke W. W. Amino acid sequence and gene organization of cytokeratin no. 19, an exceptional tail-less intermediate filament protein. EMBO J. 1986 Aug;5(8):1865–1875. doi: 10.1002/j.1460-2075.1986.tb04438.x. [DOI] [PMC free article] [PubMed] [Google Scholar]
  14. Bailly A., Atger M., Atger P., Cerbon M. A., Alizon M., Vu Haï M. T., Logeat F., Milgrom E. The rabbit uteroglobin gene. Structure and interaction with the progesterone receptor. J Biol Chem. 1983 Sep 10;258(17):10384–10389. [PubMed] [Google Scholar]
  15. Baker R. T., Board P. G. The human ubiquitin gene family: structure of a gene and pseudogenes from the Ub B subfamily. Nucleic Acids Res. 1987 Jan 26;15(2):443–463. doi: 10.1093/nar/15.2.443. [DOI] [PMC free article] [PubMed] [Google Scholar]
  16. Balcarek J. M., Cowan N. J. Structure of the mouse glial fibrillary acidic protein gene: implications for the evolution of the intermediate filament multigene family. Nucleic Acids Res. 1985 Aug 12;13(15):5527–5543. doi: 10.1093/nar/13.15.5527. [DOI] [PMC free article] [PubMed] [Google Scholar]
  17. Bao J. J., Sifers R. N., Kidd V. J., Ledley F. D., Woo S. L. Molecular evolution of serpins: homologous structure of the human alpha 1-antichymotrypsin and alpha 1-antitrypsin genes. Biochemistry. 1987 Dec 1;26(24):7755–7759. doi: 10.1021/bi00398a033. [DOI] [PubMed] [Google Scholar]
  18. Barbas J. A., Chaix J. C., Steinmetz M., Goridis C. Differential splicing and alternative polyadenylation generates distinct NCAM transcripts and proteins in the mouse. EMBO J. 1988 Mar;7(3):625–632. doi: 10.1002/j.1460-2075.1988.tb02856.x. [DOI] [PMC free article] [PubMed] [Google Scholar]
  19. Barsh G. S., Roush C. L., Bonadio J., Byers P. H., Gelinas R. E. Intron-mediated recombination may cause a deletion in an alpha 1 type I collagen chain in a lethal form of osteogenesis imperfecta. Proc Natl Acad Sci U S A. 1985 May;82(9):2870–2874. doi: 10.1073/pnas.82.9.2870. [DOI] [PMC free article] [PubMed] [Google Scholar]
  20. Barta A., Richards R. I., Baxter J. D., Shine J. Primary structure and evolution of rat growth hormone gene. Proc Natl Acad Sci U S A. 1981 Aug;78(8):4867–4871. doi: 10.1073/pnas.78.8.4867. [DOI] [PMC free article] [PubMed] [Google Scholar]
  21. Basi G. S., Storti R. V. Structure and DNA sequence of the tropomyosin I gene from Drosophila melanogaster. J Biol Chem. 1986 Jan 15;261(2):817–827. [PubMed] [Google Scholar]
  22. Beccari E., Mazzetti P. The nucleotide sequence of the ribosomal protein L14 gene of Xenopus laevis. Nucleic Acids Res. 1987 Feb 25;15(4):1870–1872. doi: 10.1093/nar/15.4.1870. [DOI] [PMC free article] [PubMed] [Google Scholar]
  23. Beisel C., Tanner J., Matsuo T., Thorley-Lawson D., Kezdy F., Kieff E. Two major outer envelope glycoproteins of Epstein-Barr virus are encoded by the same gene. J Virol. 1985 Jun;54(3):665–674. doi: 10.1128/jvi.54.3.665-674.1985. [DOI] [PMC free article] [PubMed] [Google Scholar]
  24. Bell G. I., Pictet R. L., Rutter W. J., Cordell B., Tischer E., Goodman H. M. Sequence of the human insulin gene. Nature. 1980 Mar 6;284(5751):26–32. doi: 10.1038/284026a0. [DOI] [PubMed] [Google Scholar]
  25. Benech P., Merlin G., Revel M., Chebath J. 3' end structure of the human (2'-5') oligo A synthetase gene: prediction of two distinct proteins with cell type-specific expression. Nucleic Acids Res. 1985 Feb 25;13(4):1267–1281. doi: 10.1093/nar/13.4.1267. [DOI] [PMC free article] [PubMed] [Google Scholar]
  26. Bensi G., Raugei G., Klefenz H., Cortese R. Structure and expression of the human haptoglobin locus. EMBO J. 1985 Jan;4(1):119–126. doi: 10.1002/j.1460-2075.1985.tb02325.x. [DOI] [PMC free article] [PubMed] [Google Scholar]
  27. Bentley D. L., Rabbitts T. H. Human immunoglobulin variable region genes--DNA sequences of two V kappa genes and a pseudogene. Nature. 1980 Dec 25;288(5792):730–733. doi: 10.1038/288730a0. [DOI] [PubMed] [Google Scholar]
  28. Benyajati C., Place A. R., Wang N., Pentz E., Sofer W. Deletions at intervening sequence splice sites in the alcohol dehydrogenase gene of Drosophila. Nucleic Acids Res. 1982 Nov 25;10(22):7261–7272. doi: 10.1093/nar/10.22.7261. [DOI] [PMC free article] [PubMed] [Google Scholar]
  29. Bergsma D. J., Chang K. S., Schwartz R. J. Novel chicken actin gene: third cytoplasmic isoform. Mol Cell Biol. 1985 May;5(5):1151–1162. doi: 10.1128/mcb.5.5.1151. [DOI] [PMC free article] [PubMed] [Google Scholar]
  30. Bernard O., Hozumi N., Tonegawa S. Sequences of mouse immunoglobulin light chain genes before and after somatic changes. Cell. 1978 Dec;15(4):1133–1144. doi: 10.1016/0092-8674(78)90041-7. [DOI] [PubMed] [Google Scholar]
  31. Bevan M., Barker R., Goldsbrough A., Jarvis M., Kavanagh T., Iturriaga G. The structure and transcription start site of a major potato tuber protein gene. Nucleic Acids Res. 1986 Jun 11;14(11):4625–4638. doi: 10.1093/nar/14.11.4625. [DOI] [PMC free article] [PubMed] [Google Scholar]
  32. Bishop D. F., Kornreich R., Desnick R. J. Structural organization of the human alpha-galactosidase A gene: further evidence for the absence of a 3' untranslated region. Proc Natl Acad Sci U S A. 1988 Jun;85(11):3903–3907. doi: 10.1073/pnas.85.11.3903. [DOI] [PMC free article] [PubMed] [Google Scholar]
  33. Blanchetot A., Wilson V., Wood D., Jeffreys A. J. The seal myoglobin gene: an unusually long globin gene. Nature. 1983 Feb 24;301(5902):732–734. doi: 10.1038/301732a0. [DOI] [PubMed] [Google Scholar]
  34. Blomberg B., Tonegawa S. DNA sequences of the joining regions of mouse lambda light chain immunoglobulin genes. Proc Natl Acad Sci U S A. 1982 Jan;79(2):530–533. doi: 10.1073/pnas.79.2.530. [DOI] [PMC free article] [PubMed] [Google Scholar]
  35. Bodescot M., Perricaudet M. Epstein-Barr virus mRNAs produced by alternative splicing. Nucleic Acids Res. 1986 Sep 11;14(17):7103–7114. doi: 10.1093/nar/14.17.7103. [DOI] [PMC free article] [PubMed] [Google Scholar]
  36. Boel E., Hansen M. T., Hjort I., Høegh I., Fiil N. P. Two different types of intervening sequences in the glucoamylase gene from Aspergillus niger. EMBO J. 1984 Jul;3(7):1581–1585. doi: 10.1002/j.1460-2075.1984.tb02014.x. [DOI] [PMC free article] [PubMed] [Google Scholar]
  37. Boggs R. T., Gregor P., Idriss S., Belote J. M., McKeown M. Regulation of sexual differentiation in D. melanogaster via alternative splicing of RNA from the transformer gene. Cell. 1987 Aug 28;50(5):739–747. doi: 10.1016/0092-8674(87)90332-1. [DOI] [PubMed] [Google Scholar]
  38. Boguski M. S., Birkenmeier E. H., Elshourbagy N. A., Taylor J. M., Gordon J. I. Evolution of the apolipoproteins. Structure of the rat apo-A-IV gene and its relationship to the human genes for apo-A-I, C-III, and E. J Biol Chem. 1986 May 15;261(14):6398–6407. [PubMed] [Google Scholar]
  39. Bond B. J., Davidson N. The Drosophila melanogaster actin 5C gene uses two transcription initiation sites and three polyadenylation sites to express multiple mRNA species. Mol Cell Biol. 1986 Jun;6(6):2080–2088. doi: 10.1128/mcb.6.6.2080. [DOI] [PMC free article] [PubMed] [Google Scholar]
  40. Bond U., Schlesinger M. J. The chicken ubiquitin gene contains a heat shock promoter and expresses an unstable mRNA in heat-shocked cells. Mol Cell Biol. 1986 Dec;6(12):4602–4610. doi: 10.1128/mcb.6.12.4602. [DOI] [PMC free article] [PubMed] [Google Scholar]
  41. Bosma P. J., van den Berg E. A., Kooistra T., Siemieniak D. R., Slightom J. L. Human plasminogen activator inhibitor-1 gene. Promoter and structural gene nucleotide sequences. J Biol Chem. 1988 Jul 5;263(19):9129–9141. [PubMed] [Google Scholar]
  42. Boss J. M., Mengler R., Okada K., Auffray C., Strominger J. L. Sequence analysis of the human major histocompatibility gene SX alpha. Mol Cell Biol. 1985 Oct;5(10):2677–2683. doi: 10.1128/mcb.5.10.2677. [DOI] [PMC free article] [PubMed] [Google Scholar]
  43. Boss J. M., Strominger J. L. Cloning and sequence analysis of the human major histocompatibility complex gene DC-3 beta. Proc Natl Acad Sci U S A. 1984 Aug;81(16):5199–5203. doi: 10.1073/pnas.81.16.5199. [DOI] [PMC free article] [PubMed] [Google Scholar]
  44. Bourbon H. M., Lapeyre B., Amalric F. Structure of the mouse nucleolin gene. The complete sequence reveals that each RNA binding domain is encoded by two independent exons. J Mol Biol. 1988 Apr 20;200(4):627–638. doi: 10.1016/0022-2836(88)90476-7. [DOI] [PubMed] [Google Scholar]
  45. Boutry M., Chua N. H. A nuclear gene encoding the beta subunit of the mitochondrial ATP synthase in Nicotiana plumbaginifolia. EMBO J. 1985 Sep;4(9):2159–2165. doi: 10.1002/j.1460-2075.1985.tb03910.x. [DOI] [PMC free article] [PubMed] [Google Scholar]
  46. Bown D., Ellis T. H., Gatehouse J. A. The sequence of a gene encoding convicilin from pea (Pisum sativum L.) shows that convicilin differs from vicilin by an insertion near the N-terminus. Biochem J. 1988 May 1;251(3):717–726. doi: 10.1042/bj2510717. [DOI] [PMC free article] [PubMed] [Google Scholar]
  47. Bown D., Levasseur M., Croy R. R., Boulter D., Gatehouse J. A. Sequence of a pseudogene in the legumin gene family of pea (Pisum sativum L.). Nucleic Acids Res. 1985 Jun 25;13(12):4527–4538. doi: 10.1093/nar/13.12.4527. [DOI] [PMC free article] [PubMed] [Google Scholar]
  48. Bowtell D. D., Simon M. A., Rubin G. M. Nucleotide sequence and structure of the sevenless gene of Drosophila melanogaster. Genes Dev. 1988 Jun;2(6):620–634. doi: 10.1101/gad.2.6.620. [DOI] [PubMed] [Google Scholar]
  49. Branlant C., Krol A., Ebel J. P., Gallinaro H., Lazar E., Jacob M. The conformation of chicken, rat and human U1A RNAs in solution. Nucleic Acids Res. 1981 Feb 25;9(4):841–858. doi: 10.1093/nar/9.4.841. [DOI] [PMC free article] [PubMed] [Google Scholar]
  50. Branlant C., Krol A., Ebel J. P., Lazar E., Gallinaro H., Jacob M., Sri-Widada J., Jeanteur P. Nucleotide sequences of nuclear U1A RNAs from chicken, rat and man. Nucleic Acids Res. 1980 Sep 25;8(18):4143–4154. doi: 10.1093/nar/8.18.4143. [DOI] [PMC free article] [PubMed] [Google Scholar]
  51. Breathnach R., Benoist C., O'Hare K., Gannon F., Chambon P. Ovalbumin gene: evidence for a leader sequence in mRNA and DNA sequences at the exon-intron boundaries. Proc Natl Acad Sci U S A. 1978 Oct;75(10):4853–4857. doi: 10.1073/pnas.75.10.4853. [DOI] [PMC free article] [PubMed] [Google Scholar]
  52. Breitbart R. E., Nadal-Ginard B. Complete nucleotide sequence of the fast skeletal troponin T gene. Alternatively spliced exons exhibit unusual interspecies divergence. J Mol Biol. 1986 Apr 5;188(3):313–324. doi: 10.1016/0022-2836(86)90157-9. [DOI] [PubMed] [Google Scholar]
  53. Brisson N., Verma D. P. Soybean leghemoglobin gene family: normal, pseudo, and truncated genes. Proc Natl Acad Sci U S A. 1982 Jul;79(13):4055–4059. doi: 10.1073/pnas.79.13.4055. [DOI] [PMC free article] [PubMed] [Google Scholar]
  54. Broderick T. P., Schaff D. A., Bertino A. M., Dush M. K., Tischfield J. A., Stambrook P. J. Comparative anatomy of the human APRT gene and enzyme: nucleotide sequence divergence and conservation of a nonrandom CpG dinucleotide arrangement. Proc Natl Acad Sci U S A. 1987 May;84(10):3349–3353. doi: 10.1073/pnas.84.10.3349. [DOI] [PMC free article] [PubMed] [Google Scholar]
  55. Brown J. W. A catalogue of splice junction and putative branch point sequences from plant introns. Nucleic Acids Res. 1986 Dec 22;14(24):9549–9559. doi: 10.1093/nar/14.24.9549. [DOI] [PMC free article] [PubMed] [Google Scholar]
  56. Brush D., Dodgson J. B., Choi O. R., Stevens P. W., Engel J. D. Replacement variant histone genes contain intervening sequences. Mol Cell Biol. 1985 Jun;5(6):1307–1317. doi: 10.1128/mcb.5.6.1307. [DOI] [PMC free article] [PubMed] [Google Scholar]
  57. Bäumlein H., Wobus U., Pustell J., Kafatos F. C. The legumin gene family: structure of a B type gene of Vicia faba and a possible legumin gene specific regulatory element. Nucleic Acids Res. 1986 Mar 25;14(6):2707–2720. doi: 10.1093/nar/14.6.2707. [DOI] [PMC free article] [PubMed] [Google Scholar]
  58. Calame K., Rogers J., Early P., Davis M., Livant D., Wall R., Hood L. Mouse Cmu heavy chain immunoglobulin gene segment contains three intervening sequences separating domains. Nature. 1980 Apr 3;284(5755):452–455. doi: 10.1038/284452a0. [DOI] [PubMed] [Google Scholar]
  59. Campbell H. D., Sanderson C. J., Wang Y., Hort Y., Martinson M. E., Tucker W. Q., Stellwagen A., Strath M., Young I. G. Isolation, structure and expression of cDNA and genomic clones for murine eosinophil differentiation factor. Comparison with other eosinophilopoietic lymphokines and identity with interleukin-5. Eur J Biochem. 1988 Jun 1;174(2):345–352. doi: 10.1111/j.1432-1033.1988.tb14104.x. [DOI] [PubMed] [Google Scholar]
  60. Campbell H. D., Tucker W. Q., Hort Y., Martinson M. E., Mayo G., Clutterbuck E. J., Sanderson C. J., Young I. G. Molecular cloning, nucleotide sequence, and expression of the gene encoding human eosinophil differentiation factor (interleukin 5). Proc Natl Acad Sci U S A. 1987 Oct;84(19):6629–6633. doi: 10.1073/pnas.84.19.6629. [DOI] [PMC free article] [PubMed] [Google Scholar]
  61. Campbell H. D., Ymer S., Fung M. C., Young I. G. Cloning and nucleotide sequence of the murine interleukin-3 gene. Eur J Biochem. 1985 Jul 15;150(2):297–304. doi: 10.1111/j.1432-1033.1985.tb09020.x. [DOI] [PubMed] [Google Scholar]
  62. Cantoral J. M., Barredo J. L., Alvarez E., Díez B., Martín J. F. Nucleotide sequence of the Penicillium chrysogenum pyrG (orotidine-5'-phosphate decarboxylase) gene. Nucleic Acids Res. 1988 Aug 25;16(16):8177–8177. doi: 10.1093/nar/16.16.8177. [DOI] [PMC free article] [PubMed] [Google Scholar]
  63. Carlsson P., Darnfors C., Olofsson S. O., Bjursell G. Analysis of the human apolipoprotein B gene; complete structure of the B-74 region. Gene. 1986;49(1):29–51. doi: 10.1016/0378-1119(86)90383-5. [DOI] [PubMed] [Google Scholar]
  64. Carroll S. L., Bergsma D. J., Schwartz R. J. Structure and complete nucleotide sequence of the chicken alpha-smooth muscle (aortic) actin gene. An actin gene which produces multiple messenger RNAs. J Biol Chem. 1986 Jul 5;261(19):8965–8976. [PubMed] [Google Scholar]
  65. Ceci J. D., Zheng Y. W., Felder M. R. Molecular analysis of mouse alcohol dehydrogenase: nucleotide sequence of the Adh-1 gene and genetic mapping of a related nucleotide sequence to chromosome 3. Gene. 1987;59(2-3):171–182. doi: 10.1016/0378-1119(87)90325-8. [DOI] [PubMed] [Google Scholar]
  66. Chan S. J., Episkopou V., Zeitlin S., Karathanasis S. K., MacKrell A., Steiner D. F., Efstratiadis A. Guinea pig preproinsulin gene: an evolutionary compromise? Proc Natl Acad Sci U S A. 1984 Aug;81(16):5046–5050. doi: 10.1073/pnas.81.16.5046. [DOI] [PMC free article] [PubMed] [Google Scholar]
  67. Chang K. S., Rothblum K. N., Schwartz R. J. The complete sequence of the chicken alpha-cardiac actin gene: a highly conserved vertebrate gene. Nucleic Acids Res. 1985 Feb 25;13(4):1223–1237. doi: 10.1093/nar/13.4.1223. [DOI] [PMC free article] [PubMed] [Google Scholar]
  68. Chen C. J., Chin J. E., Ueda K., Clark D. P., Pastan I., Gottesman M. M., Roninson I. B. Internal duplication and homology with bacterial transport proteins in the mdr1 (P-glycoprotein) gene from multidrug-resistant human cells. Cell. 1986 Nov 7;47(3):381–389. doi: 10.1016/0092-8674(86)90595-7. [DOI] [PubMed] [Google Scholar]
  69. Chen C. N., Malone T., Beckendorf S. K., Davis R. L. At least two genes reside within a large intron of the dunce gene of Drosophila. Nature. 1987 Oct 22;329(6141):721–724. doi: 10.1038/329721a0. [DOI] [PubMed] [Google Scholar]
  70. Chen J., Varner J. E. An extracellular matrix protein in plants: characterization of a genomic clone for carrot extensin. EMBO J. 1985 Sep;4(9):2145–2151. doi: 10.1002/j.1460-2075.1985.tb03908.x. [DOI] [PMC free article] [PubMed] [Google Scholar]
  71. Chen M. J., Shimada T., Moulton A. D., Cline A., Humphries R. K., Maizel J., Nienhuis A. W. The functional human dihydrofolate reductase gene. J Biol Chem. 1984 Mar 25;259(6):3933–3943. [PubMed] [Google Scholar]
  72. Chevillard M., Couble P., Prudhomme J. C. Complete nucleotide sequence of the gene encoding the Bombyx mori silk protein P25 and predicted amino acid sequence of the protein. Nucleic Acids Res. 1986 Aug 11;14(15):6341–6342. doi: 10.1093/nar/14.15.6341. [DOI] [PMC free article] [PubMed] [Google Scholar]
  73. Chisholm G. E., Henner D. J. Multiple early transcripts and splicing of the Autographa californica nuclear polyhedrosis virus IE-1 gene. J Virol. 1988 Sep;62(9):3193–3200. doi: 10.1128/jvi.62.9.3193-3200.1988. [DOI] [PMC free article] [PubMed] [Google Scholar]
  74. Chou H. S., Anderson S. J., Louie M. C., Godambe S. A., Pozzi M. R., Behlke M. A., Huppi K., Loh D. Y. Tandem linkage and unusual RNA splicing of the T-cell receptor beta-chain variable-region genes. Proc Natl Acad Sci U S A. 1987 Apr;84(7):1992–1996. doi: 10.1073/pnas.84.7.1992. [DOI] [PMC free article] [PubMed] [Google Scholar]
  75. Chrivia J. C., Uhler M. D., McKnight G. S. Characterization of genomic clones coding for the C alpha and C beta subunits of mouse cAMP-dependent protein kinase. J Biol Chem. 1988 Apr 25;263(12):5739–5744. [PubMed] [Google Scholar]
  76. Chung D. W., Que B. G., Rixon M. W., Mace M., Jr, Davie E. W. Characterization of complementary deoxyribonucleic acid and genomic deoxyribonucleic acid for the beta chain of human fibrinogen. Biochemistry. 1983 Jun 21;22(13):3244–3250. doi: 10.1021/bi00282a032. [DOI] [PubMed] [Google Scholar]
  77. Clark B. D., Collins K. L., Gandy M. S., Webb A. C., Auron P. E. Genomic sequence for human prointerleukin 1 beta: possible evolution from a reverse transcribed prointerleukin 1 alpha gene. Nucleic Acids Res. 1986 Oct 24;14(20):7897–7914. doi: 10.1093/nar/14.20.7897. [DOI] [PMC free article] [PubMed] [Google Scholar]
  78. Clements J. M., Roberts C. F. Transcription and processing signals in the 3-phosphoglycerate kinase (PGK) gene from Aspergillus nidulans. Gene. 1986;44(1):97–105. doi: 10.1016/0378-1119(86)90047-8. [DOI] [PubMed] [Google Scholar]
  79. Cochet M., Chang A. C., Cohen S. N. Characterization of the structural gene and putative 5'-regulatory sequences for human proopiomelanocortin. Nature. 1982 May 27;297(5864):335–339. doi: 10.1038/297335a0. [DOI] [PubMed] [Google Scholar]
  80. Coffino P., Chen E. L. Nucleotide sequence of the mouse ornithine decarboxylase gene. Nucleic Acids Res. 1988 Mar 25;16(6):2731–2732. doi: 10.1093/nar/16.6.2731. [DOI] [PMC free article] [PubMed] [Google Scholar]
  81. Cognet M., Lone Y. C., Vaulont S., Kahn A., Marie J. Structure of the rat L-type pyruvate kinase gene. J Mol Biol. 1987 Jul 5;196(1):11–25. doi: 10.1016/0022-2836(87)90507-9. [DOI] [PubMed] [Google Scholar]
  82. Cohn V. H., Moore G. P. Organization and evolution of the alcohol dehydrogenase gene in Drosophila. Mol Biol Evol. 1988 Mar;5(2):154–166. doi: 10.1093/oxfordjournals.molbev.a040487. [DOI] [PubMed] [Google Scholar]
  83. Cook J. L., Bewley G. C., Shaffer J. B. Drosophila sn-glycerol-3-phosphate dehydrogenase isozymes are generated by alternate pathways of RNA processing resulting in different carboxyl-terminal amino acid sequences. J Biol Chem. 1988 Aug 5;263(22):10858–10864. [PubMed] [Google Scholar]
  84. Cool D. E., MacGillivray R. T. Characterization of the human blood coagulation factor XII gene. Intron/exon gene organization and analysis of the 5'-flanking region. J Biol Chem. 1987 Oct 5;262(28):13662–13673. [PubMed] [Google Scholar]
  85. Cooper A. D., Crain W. R., Jr Complete nucleotide sequence of a sea urchin actin gene. Nucleic Acids Res. 1982 Jul 10;10(13):4081–4092. doi: 10.1093/nar/10.13.4081. [DOI] [PMC free article] [PubMed] [Google Scholar]
  86. Coruzzi G., Broglie R., Edwards C., Chua N. H. Tissue-specific and light-regulated expression of a pea nuclear gene encoding the small subunit of ribulose-1,5-bisphosphate carboxylase. EMBO J. 1984 Aug;3(8):1671–1679. doi: 10.1002/j.1460-2075.1984.tb02031.x. [DOI] [PMC free article] [PubMed] [Google Scholar]
  87. Costanzo F., Colombo M., Staempfli S., Santoro C., Marone M., Frank R., Delius H., Cortese R. Structure of gene and pseudogenes of human apoferritin H. Nucleic Acids Res. 1986 Jan 24;14(2):721–736. doi: 10.1093/nar/14.2.721. [DOI] [PMC free article] [PubMed] [Google Scholar]
  88. Crabtree G. R., Comeau C. M., Fowlkes D. M., Fornace A. J., Jr, Malley J. D., Kant J. A. Evolution and structure of the fibrinogen genes. Random insertion of introns or selective loss? J Mol Biol. 1985 Sep 5;185(1):1–19. doi: 10.1016/0022-2836(85)90179-2. [DOI] [PubMed] [Google Scholar]
  89. Craik C. S., Choo Q. L., Swift G. H., Quinto C., MacDonald R. J., Rutter W. J. Structure of two related rat pancreatic trypsin genes. J Biol Chem. 1984 Nov 25;259(22):14255–14264. [PubMed] [Google Scholar]
  90. Crouse G. F., Simonsen C. C., McEwan R. N., Schimke R. T. Structure of amplified normal and variant dihydrofolate reductase genes in mouse sarcoma S180 cells. J Biol Chem. 1982 Jul 10;257(13):7887–7897. [PubMed] [Google Scholar]
  91. Czarnecka E., Nagao R. T., Key J. L., Gurley W. B. Characterization of Gmhsp26-A, a stress gene encoding a divergent heat shock protein of soybean: heavy-metal-induced inhibition of intron processing. Mol Cell Biol. 1988 Mar;8(3):1113–1122. doi: 10.1128/mcb.8.3.1113. [DOI] [PMC free article] [PubMed] [Google Scholar]
  92. D'Onofrio C., Colantuoni V., Cortese R. Structure and cell-specific expression of a cloned human retinol binding protein gene: the 5'-flanking region contains hepatoma specific transcriptional signals. EMBO J. 1985 Aug;4(8):1981–1989. doi: 10.1002/j.1460-2075.1985.tb03881.x. [DOI] [PMC free article] [PubMed] [Google Scholar]
  93. Dabeva M. D., Warner J. R. The yeast ribosomal protein L32 and its gene. J Biol Chem. 1987 Nov 25;262(33):16055–16059. [PubMed] [Google Scholar]
  94. Das H. K., Lawrance S. K., Weissman S. M. Structure and nucleotide sequence of the heavy chain gene of HLA-DR. Proc Natl Acad Sci U S A. 1983 Jun;80(12):3543–3547. doi: 10.1073/pnas.80.12.3543. [DOI] [PMC free article] [PubMed] [Google Scholar]
  95. DeNoto F. M., Moore D. D., Goodman H. M. Human growth hormone DNA sequence and mRNA structure: possible alternative splicing. Nucleic Acids Res. 1981 Aug 11;9(15):3719–3730. doi: 10.1093/nar/9.15.3719. [DOI] [PMC free article] [PubMed] [Google Scholar]
  96. DePinho R. A., Legouy E., Feldman L. B., Kohl N. E., Yancopoulos G. D., Alt F. W. Structure and expression of the murine N-myc gene. Proc Natl Acad Sci U S A. 1986 Mar;83(6):1827–1831. doi: 10.1073/pnas.83.6.1827. [DOI] [PMC free article] [PubMed] [Google Scholar]
  97. Degen S. J., Davie E. W. Nucleotide sequence of the gene for human prothrombin. Biochemistry. 1987 Sep 22;26(19):6165–6177. doi: 10.1021/bi00393a033. [DOI] [PubMed] [Google Scholar]
  98. Degen S. J., Heckel J. L., Reich E., Degen J. L. The murine urokinase-type plasminogen activator gene. Biochemistry. 1987 Dec 15;26(25):8270–8279. doi: 10.1021/bi00399a038. [DOI] [PubMed] [Google Scholar]
  99. Degen S. J., Rajput B., Reich E. The human tissue plasminogen activator gene. J Biol Chem. 1986 May 25;261(15):6972–6985. [PubMed] [Google Scholar]
  100. Degrave W., Tavernier J., Duerinck F., Plaetinck G., Devos R., Fiers W. Cloning and structure of the human interleukin 2 chromosomal gene. EMBO J. 1983;2(12):2349–2353. doi: 10.1002/j.1460-2075.1983.tb01745.x. [DOI] [PMC free article] [PubMed] [Google Scholar]
  101. Delaey B., Dirckx L., Decourt J. L., Claessens F., Peeters B., Rombauts W. Rat prostatic binding protein: the complete sequence of the C2 gene and its flanking regions. Nucleic Acids Res. 1987 Feb 25;15(4):1627–1641. doi: 10.1093/nar/15.4.1627. [DOI] [PMC free article] [PubMed] [Google Scholar]
  102. Deng T. L., Li D. W., Jenh C. H., Johnson L. F. Structure of the gene for mouse thymidylate synthase. Locations of introns and multiple transcriptional start sites. J Biol Chem. 1986 Dec 5;261(34):16000–16005. [PubMed] [Google Scholar]
  103. Dennis E. S., Sachs M. M., Gerlach W. L., Finnegan E. J., Peacock W. J. Molecular analysis of the alcohol dehydrogenase 2 (Adh2) gene of maize. Nucleic Acids Res. 1985 Feb 11;13(3):727–743. doi: 10.1093/nar/13.3.727. [DOI] [PMC free article] [PubMed] [Google Scholar]
  104. Dente L., Ciliberto G., Cortese R. Structure of the human alpha 1-acid glycoprotein gene: sequence homology with other human acute phase protein genes. Nucleic Acids Res. 1985 Jun 11;13(11):3941–3952. doi: 10.1093/nar/13.11.3941. [DOI] [PMC free article] [PubMed] [Google Scholar]
  105. Derynck R., Rhee L., Chen E. Y., Van Tilburg A. Intron-exon structure of the human transforming growth factor-beta precursor gene. Nucleic Acids Res. 1987 Apr 10;15(7):3188–3189. doi: 10.1093/nar/15.7.3188. [DOI] [PMC free article] [PubMed] [Google Scholar]
  106. Deschenes R. J., Haun R. S., Funckes C. L., Dixon J. E. A gene encoding rat cholecystokinin. Isolation, nucleotide sequence, and promoter activity. J Biol Chem. 1985 Jan 25;260(2):1280–1286. [PubMed] [Google Scholar]
  107. DiLella A. G., Kwok S. C., Ledley F. D., Marvit J., Woo S. L. Molecular structure and polymorphic map of the human phenylalanine hydroxylase gene. Biochemistry. 1986 Feb 25;25(4):743–749. doi: 10.1021/bi00352a001. [DOI] [PubMed] [Google Scholar]
  108. DiLella A. G., Marvit J., Lidsky A. S., Güttler F., Woo S. L. Tight linkage between a splicing mutation and a specific DNA haplotype in phenylketonuria. 1986 Aug 28-Sep 3Nature. 322(6082):799–803. doi: 10.1038/322799a0. [DOI] [PubMed] [Google Scholar]
  109. Dickson L. A., Ninomiya Y., Bernard M. P., Pesciotta D. M., Parsons J., Green G., Eikenberry E. F., de Crombrugghe B., Vogeli G., Pastan I. The exon/intron structure of the 3'-region of the pro alpha 2(I) collagen gene. J Biol Chem. 1981 Aug 25;256(16):8407–8415. [PubMed] [Google Scholar]
  110. Dobner P. R., Kislauskis E., Wentworth B. M., Villa-Komaroff L. Alternative 5' exons either provide or deny an initiator methionine codon to the same alpha-tubulin coding region. Nucleic Acids Res. 1987 Jan 12;15(1):199–218. doi: 10.1093/nar/15.1.199. [DOI] [PMC free article] [PubMed] [Google Scholar]
  111. Dodgson J. B., Engel J. D. The nucleotide sequence of the adult chicken alpha-globin genes. J Biol Chem. 1983 Apr 10;258(7):4623–4629. [PubMed] [Google Scholar]
  112. Dodgson J. B., Stadt S. J., Choi O. R., Dolan M., Fischer H. D., Engel J. D. The nucleotide sequence of the embryonic chicken beta-type globin genes. J Biol Chem. 1983 Oct 25;258(20):12685–12692. [PubMed] [Google Scholar]
  113. Dolan M., Dodgson J. B., Engel J. D. Analysis of the adult chicken beta-globin gene. Nucleotide sequence of the locus, microheterogeneity at the 5'-end of beta-globin mRNA, and aberrant nuclear RNA species. J Biol Chem. 1983 Mar 25;258(6):3983–3990. [PubMed] [Google Scholar]
  114. Doyle J. J., Schuler M. A., Godette W. D., Zenger V., Beachy R. N., Slightom J. L. The glycosylated seed storage proteins of Glycine max and Phaseolus vulgaris. Structural homologies of genes and proteins. J Biol Chem. 1986 Jul 15;261(20):9228–9238. [PubMed] [Google Scholar]
  115. Drinkwater C. C., Evans B. A., Richards R. I. Mouse glandular kallikrein genes: identification and characterization of the genes encoding the epidermal growth factor binding proteins. Biochemistry. 1987 Oct 20;26(21):6750–6756. doi: 10.1021/bi00395a026. [DOI] [PubMed] [Google Scholar]
  116. Drinkwater C. C., Richards R. I. Sequence of the mouse glandular kallikrein gene, mGK-5. Nucleic Acids Res. 1987 Dec 10;15(23):10052–10052. doi: 10.1093/nar/15.23.10052. [DOI] [PMC free article] [PubMed] [Google Scholar]
  117. Drouin J., Chamberland M., Charron J., Jeannotte L., Nemer M. Structure of the rat pro-opiomelanocortin (POMC) gene. FEBS Lett. 1985 Nov 25;193(1):54–58. doi: 10.1016/0014-5793(85)80078-8. [DOI] [PubMed] [Google Scholar]
  118. Dudov K. P., Perry R. P. The gene family encoding the mouse ribosomal protein L32 contains a uniquely expressed intron-containing gene and an unmutated processed gene. Cell. 1984 Jun;37(2):457–468. doi: 10.1016/0092-8674(84)90376-3. [DOI] [PubMed] [Google Scholar]
  119. Dull T. J., Gray A., Hayflick J. S., Ullrich A. Insulin-like growth factor II precursor gene organization in relation to insulin gene family. 1984 Aug 30-Sep 5Nature. 310(5980):777–781. doi: 10.1038/310777a0. [DOI] [PubMed] [Google Scholar]
  120. Dush M. K., Sikela J. M., Khan S. A., Tischfield J. A., Stambrook P. J. Nucleotide sequence and organization of the mouse adenine phosphoribosyltransferase gene: presence of a coding region common to animal and bacterial phosphoribosyltransferases that has a variable intron/exon arrangement. Proc Natl Acad Sci U S A. 1985 May;82(9):2731–2735. doi: 10.1073/pnas.82.9.2731. [DOI] [PMC free article] [PubMed] [Google Scholar]
  121. Dworniczak B., Mirault M. E. Structure and expression of a human gene coding for a 71 kd heat shock 'cognate' protein. Nucleic Acids Res. 1987 Jul 10;15(13):5181–5197. doi: 10.1093/nar/15.13.5181. [DOI] [PMC free article] [PubMed] [Google Scholar]
  122. Early P., Nottenburg C., Weissman I., Hood L. Immunoglobulin gene rearrangements in normal mouse B cells. Mol Cell Biol. 1982 Jul;2(7):829–836. doi: 10.1128/mcb.2.7.829. [DOI] [PMC free article] [PubMed] [Google Scholar]
  123. Eckert R. L., Green H. Structure and evolution of the human involucrin gene. Cell. 1986 Aug 15;46(4):583–589. doi: 10.1016/0092-8674(86)90884-6. [DOI] [PubMed] [Google Scholar]
  124. Eldridge J., Zehner Z., Paterson B. M. Nucleotide sequence of the chicken cardiac alpha actin gene: absence of strong homologies in the promoter and 3'-untranslated regions with the skeletal alpha actin sequence. Gene. 1985;36(1-2):55–63. doi: 10.1016/0378-1119(85)90069-1. [DOI] [PubMed] [Google Scholar]
  125. Ellison J. W., Berson B. J., Hood L. E. The nucleotide sequence of a human immunoglobulin C gamma1 gene. Nucleic Acids Res. 1982 Jul 10;10(13):4071–4079. doi: 10.1093/nar/10.13.4071. [DOI] [PMC free article] [PubMed] [Google Scholar]
  126. Ellison J., Hood L. Linkage and sequence homology of two human immunoglobulin gamma heavy chain constant region genes. Proc Natl Acad Sci U S A. 1982 Mar;79(6):1984–1988. doi: 10.1073/pnas.79.6.1984. [DOI] [PMC free article] [PubMed] [Google Scholar]
  127. Elshourbagy N. A., Walker D. W., Paik Y. K., Boguski M. S., Freeman M., Gordon J. I., Taylor J. M. Structure and expression of the human apolipoprotein A-IV gene. J Biol Chem. 1987 Jun 15;262(17):7973–7981. [PubMed] [Google Scholar]
  128. Emorine L., Max E. E. Structural analysis of a rabbit immunoglobulin kappa 2 J-C locus reveals multiple deletions. Nucleic Acids Res. 1983 Dec 20;11(24):8877–8890. doi: 10.1093/nar/11.24.8877. [DOI] [PMC free article] [PubMed] [Google Scholar]
  129. Engel J. D., Rusling D. J., McCune K. C., Dodgson J. B. Unusual structure of the chicken embryonic alpha-globin gene, pi'. Proc Natl Acad Sci U S A. 1983 Mar;80(5):1392–1396. doi: 10.1073/pnas.80.5.1392. [DOI] [PMC free article] [PubMed] [Google Scholar]
  130. Erba H. P., Eddy R., Shows T., Kedes L., Gunning P. Structure, chromosome location, and expression of the human gamma-actin gene: differential evolution, location, and expression of the cytoskeletal beta- and gamma-actin genes. Mol Cell Biol. 1988 Apr;8(4):1775–1789. doi: 10.1128/mcb.8.4.1775. [DOI] [PMC free article] [PubMed] [Google Scholar]
  131. Erbil C., Niessing J. Chromosomal arrangement of the duck alpha-globin genes and primary structure of the embryonic alpha-globin gene pi. Gene. 1984 Dec;32(1-2):161–170. doi: 10.1016/0378-1119(84)90044-1. [DOI] [PubMed] [Google Scholar]
  132. Erbil C., Niessing J. The complete nucleotide sequence of the duck alpha A-globin gene. Gene. 1982 Dec;20(2):211–217. doi: 10.1016/0378-1119(82)90040-3. [DOI] [PubMed] [Google Scholar]
  133. Erbil C., Niessing J. The primary structure of the duck alpha D-globin gene: an unusual 5' splice junction sequence. EMBO J. 1983;2(8):1339–1343. doi: 10.1002/j.1460-2075.1983.tb01589.x. [DOI] [PMC free article] [PubMed] [Google Scholar]
  134. Esumi H., Takahashi Y., Sato S., Nagase S., Sugimura T. A seven-base-pair deletion in an intron of the albumin gene of analbuminemic rats. Proc Natl Acad Sci U S A. 1983 Jan;80(1):95–99. doi: 10.1073/pnas.80.1.95. [DOI] [PMC free article] [PubMed] [Google Scholar]
  135. Evans B. A., Richards R. I. Genes for the alpha and gamma subunits of mouse nerve growth factor are contiguous. EMBO J. 1985 Jan;4(1):133–138. doi: 10.1002/j.1460-2075.1985.tb02327.x. [DOI] [PMC free article] [PubMed] [Google Scholar]
  136. Evans B. A., Yun Z. X., Close J. A., Tregear G. W., Kitamura N., Nakanishi S., Callen D. F., Baker E., Hyland V. J., Sutherland G. R. Structure and chromosomal localization of the human renal kallikrein gene. Biochemistry. 1988 May 3;27(9):3124–3129. doi: 10.1021/bi00409a003. [DOI] [PubMed] [Google Scholar]
  137. Eveleth D. D., Gietz R. D., Spencer C. A., Nargang F. E., Hodgetts R. B., Marsh J. L. Sequence and structure of the dopa decarboxylase gene of Drosophila: evidence for novel RNA splicing variants. EMBO J. 1986 Oct;5(10):2663–2672. doi: 10.1002/j.1460-2075.1986.tb04549.x. [DOI] [PMC free article] [PubMed] [Google Scholar]
  138. Eveleth D. D., Jr, Marsh J. L. Sequence and expression of the Cc gene, a member of the dopa decarboxylase gene cluster of Drosophila: possible translational regulation. Nucleic Acids Res. 1986 Aug 11;14(15):6169–6183. doi: 10.1093/nar/14.15.6169. [DOI] [PMC free article] [PubMed] [Google Scholar]
  139. Falany C. N., McQuiddy P., Kasper C. B. Structure and organization of the microsomal xenobiotic epoxide hydrolase gene. J Biol Chem. 1987 Apr 25;262(12):5924–5930. [PubMed] [Google Scholar]
  140. Favaloro J. M., Coppel R. L., Corcoran L. M., Foote S. J., Brown G. V., Anders R. F., Kemp D. J. Structure of the RESA gene of Plasmodium falciparum. Nucleic Acids Res. 1986 Nov 11;14(21):8265–8277. doi: 10.1093/nar/14.21.8265. [DOI] [PMC free article] [PubMed] [Google Scholar]
  141. Ferrari S., Calabretta B., deRiel J. K., Battini R., Ghezzo F., Lauret E., Griffin C., Emanuel B. S., Gurrieri F., Baserga R. Structural and functional analysis of a growth-regulated gene, the human calcyclin. J Biol Chem. 1987 Jun 15;262(17):8325–8332. [PubMed] [Google Scholar]
  142. Fiddes J. C., Goodman H. M. The gene encoding the common alpha subunit of the four human glycoprotein hormones. J Mol Appl Genet. 1981;1(1):3–18. [PubMed] [Google Scholar]
  143. Finer M. H., Aho S., Gerstenfeld L. C., Boedtker H., Doty P. Unusual DNA sequences located within the promoter region and the first intron of the chicken pro-alpha 1(I) collagen gene. J Biol Chem. 1987 Sep 25;262(27):13323–13332. [PubMed] [Google Scholar]
  144. Fischer H. D., Dodgson J. B., Hughes S., Engel J. D. An unusual 5' splice sequence is efficiently utilized in vivo. Proc Natl Acad Sci U S A. 1984 May;81(9):2733–2737. doi: 10.1073/pnas.81.9.2733. [DOI] [PMC free article] [PubMed] [Google Scholar]
  145. Flanagan J. G., Rabbitts T. H. The sequence of a human immunoglobulin epsilon heavy chain constant region gene, and evidence for three non-allelic genes. EMBO J. 1982;1(5):655–660. doi: 10.1002/j.1460-2075.1982.tb01223.x. [DOI] [PMC free article] [PubMed] [Google Scholar]
  146. Fojo S. S., Law S. W., Brewer H. B., Jr The human preproapolipoprotein C-II gene. Complete nucleic acid sequence and genomic organization. FEBS Lett. 1987 Mar 9;213(1):221–226. doi: 10.1016/0014-5793(87)81495-3. [DOI] [PubMed] [Google Scholar]
  147. Fornwald J. A., Kuncio G., Peng I., Ordahl C. P. The complete nucleotide sequence of the chick a-actin gene and its evolutionary relationship to the actin gene family. Nucleic Acids Res. 1982 Jul 10;10(13):3861–3876. doi: 10.1093/nar/10.13.3861. [DOI] [PMC free article] [PubMed] [Google Scholar]
  148. Foster D. C., Yoshitake S., Davie E. W. The nucleotide sequence of the gene for human protein C. Proc Natl Acad Sci U S A. 1985 Jul;82(14):4673–4677. doi: 10.1073/pnas.82.14.4673. [DOI] [PMC free article] [PubMed] [Google Scholar]
  149. Fouts D., Ganguly R., Gutierrez A. G., Lucchesi J. C., Manning J. E. Nucleotide sequence of the Drosophila glucose-6-phosphate dehydrogenase gene and comparison with the homologous human gene. Gene. 1988 Mar 31;63(2):261–275. doi: 10.1016/0378-1119(88)90530-6. [DOI] [PubMed] [Google Scholar]
  150. Frei E., Schuh R., Baumgartner S., Burri M., Noll M., Jürgens G., Seifert E., Nauber U., Jäckle H. Molecular characterization of spalt, a homeotic gene required for head and tail development in the Drosophila embryo. EMBO J. 1988 Jan;7(1):197–204. doi: 10.1002/j.1460-2075.1988.tb02800.x. [DOI] [PMC free article] [PubMed] [Google Scholar]
  151. Freytag S. O., Beaudet A. L., Bock H. G., O'Brien W. E. Molecular structure of the human argininosuccinate synthetase gene: occurrence of alternative mRNA splicing. Mol Cell Biol. 1984 Oct;4(10):1978–1984. doi: 10.1128/mcb.4.10.1978. [DOI] [PMC free article] [PubMed] [Google Scholar]
  152. Fujita T., Takaoka C., Matsui H., Taniguchi T. Structure of the human interleukin 2 gene. Proc Natl Acad Sci U S A. 1983 Dec;80(24):7437–7441. doi: 10.1073/pnas.80.24.7437. [DOI] [PMC free article] [PubMed] [Google Scholar]
  153. Fujiwara K. T., Ashida K., Nishina H., Iba H., Miyajima N., Nishizawa M., Kawai S. The chicken c-fos gene: cloning and nucleotide sequence analysis. J Virol. 1987 Dec;61(12):4012–4018. doi: 10.1128/jvi.61.12.4012-4018.1987. [DOI] [PMC free article] [PubMed] [Google Scholar]
  154. Fujiyama K., Takemura H., Shibayama S., Kobayashi K., Choi J. K., Shinmyo A., Takano M., Yamada Y., Okada H. Structure of the horseradish peroxidase isozyme C genes. Eur J Biochem. 1988 May 2;173(3):681–687. doi: 10.1111/j.1432-1033.1988.tb14052.x. [DOI] [PubMed] [Google Scholar]
  155. Furutani Y., Notake M., Fukui T., Ohue M., Nomura H., Yamada M., Nakamura S. Complete nucleotide sequence of the gene for human interleukin 1 alpha. Nucleic Acids Res. 1986 Apr 25;14(8):3167–3179. doi: 10.1093/nar/14.8.3167. [DOI] [PMC free article] [PubMed] [Google Scholar]
  156. Fuse A., Fujita T., Yasumitsu H., Kashima N., Hasegawa K., Taniguchi T. Organization and structure of the mouse interleukin-2 gene. Nucleic Acids Res. 1984 Dec 21;12(24):9323–9331. doi: 10.1093/nar/12.24.9323. [DOI] [PMC free article] [PubMed] [Google Scholar]
  157. Fyrberg E. A., Bond B. J., Hershey N. D., Mixter K. S., Davidson N. The actin genes of Drosophila: protein coding regions are highly conserved but intron positions are not. Cell. 1981 Apr;24(1):107–116. doi: 10.1016/0092-8674(81)90506-7. [DOI] [PubMed] [Google Scholar]
  158. Gallwitz D., Sures I. Structure of a split yeast gene: complete nucleotide sequence of the actin gene in Saccharomyces cerevisiae. Proc Natl Acad Sci U S A. 1980 May;77(5):2546–2550. doi: 10.1073/pnas.77.5.2546. [DOI] [PMC free article] [PubMed] [Google Scholar]
  159. Garabedian M. J., Shirras A. D., Bownes M., Wensink P. C. The nucleotide sequence of the gene coding for Drosophila melanogaster yolk protein 3. Gene. 1987;55(1):1–8. doi: 10.1016/0378-1119(87)90242-3. [DOI] [PubMed] [Google Scholar]
  160. Garner I., Minty A. J., Alonso S., Barton P. J., Buckingham M. E. A 5' duplication of the alpha-cardiac actin gene in BALB/c mice is associated with abnormal levels of alpha-cardiac and alpha-skeletal actin mRNAs in adult cardiac tissue. EMBO J. 1986 Oct;5(10):2559–2567. doi: 10.1002/j.1460-2075.1986.tb04535.x. [DOI] [PMC free article] [PubMed] [Google Scholar]
  161. Gatehouse J. A., Bown D., Gilroy J., Levasseur M., Castleton J., Ellis T. H. Two genes encoding 'minor' legumin polypeptides in pea (Pisum sativum L.). Characterization and complete sequence of the LegJ gene. Biochem J. 1988 Feb 15;250(1):15–24. doi: 10.1042/bj2500015. [DOI] [PMC free article] [PubMed] [Google Scholar]
  162. Geraghty D. E., Koller B. H., Orr H. T. A human major histocompatibility complex class I gene that encodes a protein with a shortened cytoplasmic segment. Proc Natl Acad Sci U S A. 1987 Dec;84(24):9145–9149. doi: 10.1073/pnas.84.24.9145. [DOI] [PMC free article] [PubMed] [Google Scholar]
  163. Gerber-Huber S., Nardelli D., Haefliger J. A., Cooper D. N., Givel F., Germond J. E., Engel J., Green N. M., Wahli W. Precursor-product relationship between vitellogenin and the yolk proteins as derived from the complete sequence of a Xenopus vitellogenin gene. Nucleic Acids Res. 1987 Jun 25;15(12):4737–4760. doi: 10.1093/nar/15.12.4737. [DOI] [PMC free article] [PubMed] [Google Scholar]
  164. Gibbs P. E., Zielinski R., Boyd C., Dugaiczyk A. Structure, polymorphism, and novel repeated DNA elements revealed by a complete sequence of the human alpha-fetoprotein gene. Biochemistry. 1987 Mar 10;26(5):1332–1343. doi: 10.1021/bi00379a020. [DOI] [PubMed] [Google Scholar]
  165. Giguére V., Isobe K., Grosveld F. Structure of the murine Thy-1 gene. EMBO J. 1985 Aug;4(8):2017–2024. doi: 10.1002/j.1460-2075.1985.tb03886.x. [DOI] [PMC free article] [PubMed] [Google Scholar]
  166. Gingeras T. R., Sciaky D., Gelinas R. E., Bing-Dong J., Yen C. E., Kelly M. M., Bullock P. A., Parsons B. L., O'Neill K. E., Roberts R. J. Nucleotide sequences from the adenovirus-2 genome. J Biol Chem. 1982 Nov 25;257(22):13475–13491. [PubMed] [Google Scholar]
  167. Gitschier J., Wood W. I., Goralka T. M., Wion K. L., Chen E. Y., Eaton D. H., Vehar G. A., Capon D. J., Lawn R. M. Characterization of the human factor VIII gene. Nature. 1984 Nov 22;312(5992):326–330. doi: 10.1038/312326a0. [DOI] [PubMed] [Google Scholar]
  168. Glanville N., Durnam D. M., Palmiter R. D. Structure of mouse metallothionein-I gene and its mRNA. Nature. 1981 Jul 16;292(5820):267–269. doi: 10.1038/292267a0. [DOI] [PubMed] [Google Scholar]
  169. Goldberg G. I., Vanin E. F., Zrolka A. M., Blattner F. R. Sequence of the gene for the constant region of the mu chain of Balb/c mouse immunoglobulin. Gene. 1981 Oct;15(1):33–42. doi: 10.1016/0378-1119(81)90102-5. [DOI] [PubMed] [Google Scholar]
  170. Goodwin R. G., Moncman C. L., Rottman F. M., Nilson J. H. Characterization and nucleotide sequence of the gene for the common alpha subunit of the bovine pituitary glycoprotein hormones. Nucleic Acids Res. 1983 Oct 11;11(19):6873–6882. doi: 10.1093/nar/11.19.6873. [DOI] [PMC free article] [PubMed] [Google Scholar]
  171. Gough N. M., Bernard O. Sequences of the joining region genes for immunoglobulin heavy chains and their role in generation of antibody diversity. Proc Natl Acad Sci U S A. 1981 Jan;78(1):509–513. doi: 10.1073/pnas.78.1.509. [DOI] [PMC free article] [PubMed] [Google Scholar]
  172. Gough N. M., Gearing D. P., King J. A., Willson T. A., Hilton D. J., Nicola N. A., Metcalf D. Molecular cloning and expression of the human homologue of the murine gene encoding myeloid leukemia-inhibitory factor. Proc Natl Acad Sci U S A. 1988 Apr;85(8):2623–2627. doi: 10.1073/pnas.85.8.2623. [DOI] [PMC free article] [PubMed] [Google Scholar]
  173. Green M. R. Pre-mRNA splicing. Annu Rev Genet. 1986;20:671–708. doi: 10.1146/annurev.ge.20.120186.003323. [DOI] [PubMed] [Google Scholar]
  174. Greenberg B. D., Bencen G. H., Seilhamer J. J., Lewicki J. A., Fiddes J. C. Nucleotide sequence of the gene encoding human atrial natriuretic factor precursor. Nature. 1984 Dec 13;312(5995):656–658. doi: 10.1038/312656a0. [DOI] [PubMed] [Google Scholar]
  175. Greenwald I. lin-12, a nematode homeotic gene, is homologous to a set of mammalian proteins that includes epidermal growth factor. Cell. 1985 Dec;43(3 Pt 2):583–590. doi: 10.1016/0092-8674(85)90230-2. [DOI] [PubMed] [Google Scholar]
  176. Gubbins E. J., Maurer R. A., Lagrimini M., Erwin C. R., Donelson J. E. Structure of the rat prolactin gene. J Biol Chem. 1980 Sep 25;255(18):8655–8662. [PubMed] [Google Scholar]
  177. Gustafsson K., Widmark E., Jonsson A. K., Servenius B., Sachs D. H., Larhammar D., Rask L., Peterson P. A. Class II genes of the human major histocompatibility complex. Evolution of the DP region as deduced from nucleotide sequences of the four genes. J Biol Chem. 1987 Jun 25;262(18):8778–8786. [PubMed] [Google Scholar]
  178. Güssow D., Rein R., Ginjaar I., Hochstenbach F., Seemann G., Kottman A., Ploegh H. L. The human beta 2-microglobulin gene. Primary structure and definition of the transcriptional unit. J Immunol. 1987 Nov 1;139(9):3132–3138. [PubMed] [Google Scholar]
  179. Haley J., Crawford R., Hudson P., Scanlon D., Tregear G., Shine J., Niall H. Porcine relaxin. Gene structure and expression. J Biol Chem. 1987 Sep 5;262(25):11940–11946. [PubMed] [Google Scholar]
  180. Hall J. L., Cowan N. J. Structural features and restricted expression of a human alpha-tubulin gene. Nucleic Acids Res. 1985 Jan 11;13(1):207–223. doi: 10.1093/nar/13.1.207. [DOI] [PMC free article] [PubMed] [Google Scholar]
  181. Hammer J. A., 3rd, Bowers B., Paterson B. M., Korn E. D. Complete nucleotide sequence and deduced polypeptide sequence of a nonmuscle myosin heavy chain gene from Acanthamoeba: evidence of a hinge in the rodlike tail. J Cell Biol. 1987 Aug;105(2):913–925. doi: 10.1083/jcb.105.2.913. [DOI] [PMC free article] [PubMed] [Google Scholar]
  182. Hanke P. D., Storti R. V. The Drosophila melanogaster tropomyosin II gene produces multiple proteins by use of alternative tissue-specific promoters and alternative splicing. Mol Cell Biol. 1988 Sep;8(9):3591–3602. doi: 10.1128/mcb.8.9.3591. [DOI] [PMC free article] [PubMed] [Google Scholar]
  183. Hanley B. A., Schuler M. A. Plant intron sequences: evidence for distinct groups of introns. Nucleic Acids Res. 1988 Jul 25;16(14B):7159–7176. doi: 10.1093/nar/16.14.7159. [DOI] [PMC free article] [PubMed] [Google Scholar]
  184. Hardison R. C., Butler E. T., 3rd, Lacy E., Maniatis T., Rosenthal N., Efstratiadis A. The structure and transcription of four linked rabbit beta-like globin genes. Cell. 1979 Dec;18(4):1285–1297. doi: 10.1016/0092-8674(79)90239-3. [DOI] [PubMed] [Google Scholar]
  185. Hardison R. C. The nucleotide sequence of rabbit embryonic globin gene beta 3. J Biol Chem. 1981 Nov 25;256(22):11780–11786. [PubMed] [Google Scholar]
  186. Hardison R. C. The nucleotide sequence of the rabbit embryonic globin gene beta 4. J Biol Chem. 1983 Jul 25;258(14):8739–8744. [PubMed] [Google Scholar]
  187. Hardman J. A., Hort Y. J., Catanzaro D. F., Tellam J. T., Baxter J. D., Morris B. J., Shine J. Primary structure of the human renin gene. DNA. 1984 Dec;3(6):457–468. doi: 10.1089/dna.1.1984.3.457. [DOI] [PubMed] [Google Scholar]
  188. Harris S. E., Mansson P. E., Tully D. B., Burkhart B. Seminal vesicle secretion IV gene: allelic difference due to a series of 20-base-pair direct tandem repeats within an intron. Proc Natl Acad Sci U S A. 1983 Nov;80(21):6460–6464. doi: 10.1073/pnas.80.21.6460. [DOI] [PMC free article] [PubMed] [Google Scholar]
  189. Harris S., Thackeray J. R., Jeffreys A. J., Weiss M. L. Nucleotide sequence analysis of the lemur beta-globin gene family: evidence for major rate fluctuations in globin polypeptide evolution. Mol Biol Evol. 1986 Nov;3(6):465–484. doi: 10.1093/oxfordjournals.molbev.a040415. [DOI] [PubMed] [Google Scholar]
  190. Hawley R. G., Shulman M. J., Murialdo H., Gibson D. M., Hozumi N. Mutant immunoglobulin genes have repetitive DNA elements inserted into their intervening sequences. Proc Natl Acad Sci U S A. 1982 Dec;79(23):7425–7429. doi: 10.1073/pnas.79.23.7425. [DOI] [PMC free article] [PubMed] [Google Scholar]
  191. Hayashi K., Makino R., Kawamura H., Arisawa A., Yoneda K. Characterization of rat c-myc and adjacent regions. Nucleic Acids Res. 1987 Aug 25;15(16):6419–6436. doi: 10.1093/nar/15.16.6419. [DOI] [PMC free article] [PubMed] [Google Scholar]
  192. Hayashi K., Yasugi S., Mizuno T. Isolation and structural analysis of embryonic chicken pepsinogen gene: avian homologue of prochymosin gene. Biochem Biophys Res Commun. 1988 Apr 29;152(2):776–782. doi: 10.1016/s0006-291x(88)80105-0. [DOI] [PubMed] [Google Scholar]
  193. Heidmann O., Rougeon F. Diversity in the rabbit immunoglobulin kappa chain variable regions is amplified by nucleotide deletions and insertions at the V-J junction. Cell. 1983 Oct;34(3):767–777. doi: 10.1016/0092-8674(83)90533-0. [DOI] [PubMed] [Google Scholar]
  194. Heidmann O., Rougeon F. Immunoglobulin kappa light-chain diversity in rabbit is based on the 3' length heterogeneity of germ-line variable genes. Nature. 1984 Sep 6;311(5981):74–76. doi: 10.1038/311074a0. [DOI] [PubMed] [Google Scholar]
  195. Heilig R., Muraskowsky R., Kloepfer C., Mandel J. L. The ovalbumin gene family: complete sequence and structure of the Y gene. Nucleic Acids Res. 1982 Jul 24;10(14):4363–4382. doi: 10.1093/nar/10.14.4363. [DOI] [PMC free article] [PubMed] [Google Scholar]
  196. Heinrich G., Gros P., Habener J. F. Glucagon gene sequence. Four of six exons encode separate functional domains of rat pre-proglucagon. J Biol Chem. 1984 Nov 25;259(22):14082–14087. [PubMed] [Google Scholar]
  197. Heinrich G., Kronenberg H. M., Potts J. T., Jr, Habener J. F. Gene encoding parathyroid hormone. Nucleotide sequence of the rat gene and deduced amino acid sequence of rat preproparathyroid hormone. J Biol Chem. 1984 Mar 10;259(5):3320–3329. [PubMed] [Google Scholar]
  198. Helfman D. M., Cheley S., Kuismanen E., Finn L. A., Yamawaki-Kataoka Y. Nonmuscle and muscle tropomyosin isoforms are expressed from a single gene by alternative RNA splicing and polyadenylation. Mol Cell Biol. 1986 Nov;6(11):3582–3595. doi: 10.1128/mcb.6.11.3582. [DOI] [PMC free article] [PubMed] [Google Scholar]
  199. Henikoff S., Sloan J. S., Kelly J. D. A Drosophila metabolic gene transcript is alternatively processed. Cell. 1983 Sep;34(2):405–414. doi: 10.1016/0092-8674(83)90374-4. [DOI] [PubMed] [Google Scholar]
  200. Henthorn P. S., Raducha M., Kadesch T., Weiss M. J., Harris H. Sequence and characterization of the human intestinal alkaline phosphatase gene. J Biol Chem. 1988 Aug 25;263(24):12011–12019. [PubMed] [Google Scholar]
  201. Hickey E., Brandon S. E., Potter R., Stein G., Stein J., Weber L. A. Sequence and organization of genes encoding the human 27 kDa heat shock protein. Nucleic Acids Res. 1986 May 27;14(10):4127–4145. doi: 10.1093/nar/14.10.4127. [DOI] [PMC free article] [PubMed] [Google Scholar]
  202. Hidaka Y., Tarlé S. A., O'Toole T. E., Kelley W. N., Palella T. D. Nucleotide sequence of the human APRT gene. Nucleic Acids Res. 1987 Nov 11;15(21):9086–9086. doi: 10.1093/nar/15.21.9086. [DOI] [PMC free article] [PubMed] [Google Scholar]
  203. Higashi Y., Yoshioka H., Yamane M., Gotoh O., Fujii-Kuriyama Y. Complete nucleotide sequence of two steroid 21-hydroxylase genes tandemly arranged in human chromosome: a pseudogene and a genuine gene. Proc Natl Acad Sci U S A. 1986 May;83(9):2841–2845. doi: 10.1073/pnas.83.9.2841. [DOI] [PMC free article] [PubMed] [Google Scholar]
  204. Hijikata M., Ishii N., Kagamiyama H., Osumi T., Hashimoto T. Structural analysis of cDNA for rat peroxisomal 3-ketoacyl-CoA thiolase. J Biol Chem. 1987 Jun 15;262(17):8151–8158. [PubMed] [Google Scholar]
  205. Hill A., Hardies S. C., Phillips S. J., Davis M. G., Hutchison C. A., 3rd, Edgell M. H. Two mouse early embryonic beta-globin gene sequences. Evolution of the nonadult beta-globins. J Biol Chem. 1984 Mar 25;259(6):3739–3747. [PubMed] [Google Scholar]
  206. Hines R. N., Levy J. B., Conrad R. D., Iversen P. L., Shen M. L., Renli A. M., Bresnick E. Gene structure and nucleotide sequence for rat cytochrome P-450c. Arch Biochem Biophys. 1985 Mar;237(2):465–476. doi: 10.1016/0003-9861(85)90300-5. [DOI] [PubMed] [Google Scholar]
  207. Hobart P. M., Fogliano M., O'Connor B. A., Schaefer I. M., Chirgwin J. M. Human renin gene: structure and sequence analysis. Proc Natl Acad Sci U S A. 1984 Aug;81(16):5026–5030. doi: 10.1073/pnas.81.16.5026. [DOI] [PMC free article] [PubMed] [Google Scholar]
  208. Hogg D., Tsui L. C., Gorin M., Breitman M. L. Characterization of the human beta-crystallin gene Hu beta A3/A1 reveals ancestral relationships among the beta gamma-crystallin superfamily. J Biol Chem. 1986 Sep 15;261(26):12420–12427. [PubMed] [Google Scholar]
  209. Holdsworth M. J., Schuch W., Grierson D. Nucleotide sequence of an ethylene-related gene from tomato. Nucleic Acids Res. 1987 Dec 23;15(24):10600–10600. doi: 10.1093/nar/15.24.10600. [DOI] [PMC free article] [PubMed] [Google Scholar]
  210. Holm I., Ollo R., Panthier J. J., Rougeon F. Evolution of aspartyl proteases by gene duplication: the mouse renin gene is organized in two homologous clusters of four exons. EMBO J. 1984 Mar;3(3):557–562. doi: 10.1002/j.1460-2075.1984.tb01846.x. [DOI] [PMC free article] [PubMed] [Google Scholar]
  211. Holmgren R., Corces V., Morimoto R., Blackman R., Meselson M. Sequence homologies in the 5' regions of four Drosophila heat-shock genes. Proc Natl Acad Sci U S A. 1981 Jun;78(6):3775–3778. doi: 10.1073/pnas.78.6.3775. [DOI] [PMC free article] [PubMed] [Google Scholar]
  212. Honjo T., Obata M., Yamawaki-Katoaka Y., Kataoka T., Kawakami T., Takahashi N., Mano Y. Cloning and complete nucleotide sequence of mouse immunoglobulin gamma 1 chain gene. Cell. 1979 Oct;18(2):559–568. doi: 10.1016/0092-8674(79)90072-2. [DOI] [PubMed] [Google Scholar]
  213. Horii A., Emi M., Tomita N., Nishide T., Ogawa M., Mori T., Matsubara K. Primary structure of human pancreatic alpha-amylase gene: its comparison with human salivary alpha-amylase gene. Gene. 1987;60(1):57–64. doi: 10.1016/0378-1119(87)90213-7. [DOI] [PubMed] [Google Scholar]
  214. Hoshimaru M., Nakanishi S. Identification of a new type of mammalian myosin heavy chain by molecular cloning. Overlap of its mRNA with preprotachykinin B mRNA. J Biol Chem. 1987 Oct 25;262(30):14625–14632. [PubMed] [Google Scholar]
  215. Hovemann B., Galler R., Walldorf U., Küpper H., Bautz E. K. Vitellogenin in Drosophila melanogaster: sequence of the yolk protein I gene and its flanking regions. Nucleic Acids Res. 1981 Sep 25;9(18):4721–4734. doi: 10.1093/nar/9.18.4721. [DOI] [PMC free article] [PubMed] [Google Scholar]
  216. Hsu S. L., Marks J., Shaw J. P., Tam M., Higgs D. R., Shen C. C., Shen C. K. Structure and expression of the human theta 1 globin gene. Nature. 1988 Jan 7;331(6151):94–96. doi: 10.1038/331094a0. [DOI] [PubMed] [Google Scholar]
  217. Huck S., Fort P., Crawford D. H., Lefranc M. P., Lefranc G. Sequence of a human immunoglobulin gamma 3 heavy chain constant region gene: comparison with the other human C gamma genes. Nucleic Acids Res. 1986 Feb 25;14(4):1779–1789. doi: 10.1093/nar/14.4.1779. [DOI] [PMC free article] [PubMed] [Google Scholar]
  218. Huckaby C. S., Conneely O. M., Beattie W. G., Dobson A. D., Tsai M. J., O'Malley B. W. Structure of the chromosomal chicken progesterone receptor gene. Proc Natl Acad Sci U S A. 1987 Dec;84(23):8380–8384. doi: 10.1073/pnas.84.23.8380. [DOI] [PMC free article] [PubMed] [Google Scholar]
  219. Hug H., Costas M., Staeheli P., Aebi M., Weissmann C. Organization of the murine Mx gene and characterization of its interferon- and virus-inducible promoter. Mol Cell Biol. 1988 Aug;8(8):3065–3079. doi: 10.1128/mcb.8.8.3065. [DOI] [PMC free article] [PubMed] [Google Scholar]
  220. Hung M. C., Wensink P. C. Sequence and structure conservation in yolk proteins and their genes. J Mol Biol. 1983 Mar 15;164(4):481–492. doi: 10.1016/0022-2836(83)90046-3. [DOI] [PubMed] [Google Scholar]
  221. Hung M. C., Wensink P. C. The sequence of the Drosophila melanogaster gene for yolk protein 1. Nucleic Acids Res. 1981 Dec 11;9(23):6407–6419. doi: 10.1093/nar/9.23.6407. [DOI] [PMC free article] [PubMed] [Google Scholar]
  222. Hurst H. C., Parker M. G. Rat prostatic steroid binding protein: DNA sequence and transcript maps of the two C3 genes. EMBO J. 1983;2(5):769–774. doi: 10.1002/j.1460-2075.1983.tb01498.x. [DOI] [PMC free article] [PubMed] [Google Scholar]
  223. Hyldig-Nielsen J. J., Jensen E. O., Paludan K., Wiborg O., Garrett R., Jørgensen P., Marcker K. A. The primary structures of two leghemoglobin genes from soybean. Nucleic Acids Res. 1982 Jan 22;10(2):689–701. doi: 10.1093/nar/10.2.689. [DOI] [PMC free article] [PubMed] [Google Scholar]
  224. Ichinose A., Davie E. W. Characterization of the gene for the a subunit of human factor XIII (plasma transglutaminase), a blood coagulation factor. Proc Natl Acad Sci U S A. 1988 Aug;85(16):5829–5833. doi: 10.1073/pnas.85.16.5829. [DOI] [PMC free article] [PubMed] [Google Scholar]
  225. Indik Z., Yeh H., Ornstein-Goldstein N., Sheppard P., Anderson N., Rosenbloom J. C., Peltonen L., Rosenbloom J. Alternative splicing of human elastin mRNA indicated by sequence analysis of cloned genomic and complementary DNA. Proc Natl Acad Sci U S A. 1987 Aug;84(16):5680–5684. doi: 10.1073/pnas.84.16.5680. [DOI] [PMC free article] [PubMed] [Google Scholar]
  226. Irwin D. M., Robertson K. A., MacGillivray R. T. Structure and evolution of the bovine prothrombin gene. J Mol Biol. 1988 Mar 5;200(1):31–45. doi: 10.1016/0022-2836(88)90331-2. [DOI] [PubMed] [Google Scholar]
  227. Ishida K., Morino T., Takagi K., Sukenaga Y. Nucleotide sequence of a human gene for glutathione peroxidase. Nucleic Acids Res. 1987 Dec 10;15(23):10051–10051. doi: 10.1093/nar/15.23.10051. [DOI] [PMC free article] [PubMed] [Google Scholar]
  228. Ishida N., Kanamori H., Noma T., Nikaido T., Sabe H., Suzuki N., Shimizu A., Honjo T. Molecular cloning and structure of the human interleukin 2 receptor gene. Nucleic Acids Res. 1985 Nov 11;13(21):7579–7589. doi: 10.1093/nar/13.21.7579. [DOI] [PMC free article] [PubMed] [Google Scholar]
  229. Ishida N., Ueda S., Hayashida H., Miyata T., Honjo T. The nucleotide sequence of the mouse immunoglobulin epsilon gene: comparison with the human epsilon gene sequence. EMBO J. 1982;1(9):1117–1123. doi: 10.1002/j.1460-2075.1982.tb01306.x. [DOI] [PMC free article] [PubMed] [Google Scholar]
  230. Ishii N., Hijikata M., Osumi T., Hashimoto T. Structural organization of the gene for rat enoyl-CoA hydratase:3-hydroxyacyl-CoA dehydrogenase bifunctional enzyme. J Biol Chem. 1987 Jun 15;262(17):8144–8150. [PubMed] [Google Scholar]
  231. Isobe M., Russo G., Haluska F. G., Croce C. M. Cloning of the gene encoding the delta subunit of the human T-cell receptor reveals its physical organization within the alpha-subunit locus and its involvement in chromosome translocations in T-cell malignancy. Proc Natl Acad Sci U S A. 1988 Jun;85(11):3933–3937. doi: 10.1073/pnas.85.11.3933. [DOI] [PMC free article] [PubMed] [Google Scholar]
  232. Ito R., Sato K., Helmer T., Jay G., Agarwal K. Structural analysis of the gene encoding human gastrin: the large intron contains an Alu sequence. Proc Natl Acad Sci U S A. 1984 Aug;81(15):4662–4666. doi: 10.1073/pnas.81.15.4662. [DOI] [PMC free article] [PubMed] [Google Scholar]
  233. Itoh H., Toyama R., Kozasa T., Tsukamoto T., Matsuoka M., Kaziro Y. Presence of three distinct molecular species of Gi protein alpha subunit. Structure of rat cDNAs and human genomic DNAs. J Biol Chem. 1988 May 15;263(14):6656–6664. [PubMed] [Google Scholar]
  234. Itoh N., Tanaka N., Funakoshi I., Kawasaki T., Mihashi S., Yamashina I. Organization of the gene for batroxobin, a thrombin-like snake venom enzyme. Homology with the trypsin/kallikrein gene family. J Biol Chem. 1988 Jun 5;263(16):7628–7631. [PubMed] [Google Scholar]
  235. Jacobs K., Shoemaker C., Rudersdorf R., Neill S. D., Kaufman R. J., Mufson A., Seehra J., Jones S. S., Hewick R., Fritsch E. F. Isolation and characterization of genomic and cDNA clones of human erythropoietin. 1985 Feb 28-Mar 6Nature. 313(6005):806–810. doi: 10.1038/313806a0. [DOI] [PubMed] [Google Scholar]
  236. Jaenichen H. R., Pech M., Lindenmaier W., Wildgruber N., Zachau H. G. Composite human VK genes and a model of their evolution. Nucleic Acids Res. 1984 Jul 11;12(13):5249–5263. doi: 10.1093/nar/12.13.5249. [DOI] [PMC free article] [PubMed] [Google Scholar]
  237. Jagd S., Vibe-Pedersen K., Magnusson S. Location of two of the introns in the antithrombin-III gene. FEBS Lett. 1985 Dec 2;193(2):213–216. doi: 10.1016/0014-5793(85)80154-x. [DOI] [PubMed] [Google Scholar]
  238. Jahn C. L., Hutchison C. A., 3rd, Phillips S. J., Weaver S., Haigwood N. L., Voliva C. F., Edgell M. H. DNA sequence organization of the beta-globin complex in the BALB/c mouse. Cell. 1980 Aug;21(1):159–168. doi: 10.1016/0092-8674(80)90123-3. [DOI] [PubMed] [Google Scholar]
  239. Jameson L., Chin W. W., Hollenberg A. N., Chang A. S., Habener J. F. The gene encoding the beta-subunit of rat luteinizing hormone. Analysis of gene structure and evolution of nucleotide sequence. J Biol Chem. 1984 Dec 25;259(24):15474–15480. [PubMed] [Google Scholar]
  240. Jeltsch J. M., Hen R., Maroteaux L., Garnier J. M., Chambon P. Sequence of the chicken ovotransferrin gene. Nucleic Acids Res. 1987 Sep 25;15(18):7643–7645. doi: 10.1093/nar/15.18.7643. [DOI] [PMC free article] [PubMed] [Google Scholar]
  241. Jeltsch J. M., Roberts M., Schatz C., Garnier J. M., Brown A. M., Chambon P. Structure of the human oestrogen-responsive gene pS2. Nucleic Acids Res. 1987 Feb 25;15(4):1401–1414. doi: 10.1093/nar/15.4.1401. [DOI] [PMC free article] [PubMed] [Google Scholar]
  242. Jenne D., Stanley K. K. Nucleotide sequence and organization of the human S-protein gene: repeating peptide motifs in the "pexin" family and a model for their evolution. Biochemistry. 1987 Oct 20;26(21):6735–6742. doi: 10.1021/bi00395a024. [DOI] [PubMed] [Google Scholar]
  243. Joh K., Arai Y., Mukai T., Hori K. Expression of three mRNA species from a single rat aldolase A gene, differing in their 5' non-coding regions. J Mol Biol. 1986 Aug 5;190(3):401–410. doi: 10.1016/0022-2836(86)90011-2. [DOI] [PubMed] [Google Scholar]
  244. Johnson L. D., Idler W. W., Zhou X. M., Roop D. R., Steinert P. M. Structure of a gene for the human epidermal 67-kDa keratin. Proc Natl Acad Sci U S A. 1985 Apr;82(7):1896–1900. doi: 10.1073/pnas.82.7.1896. [DOI] [PMC free article] [PubMed] [Google Scholar]
  245. Johnson P. J., Foran D. R., Moore G. P. Organization and evolution of the actin gene family in sea urchins. Mol Cell Biol. 1983 Oct;3(10):1824–1833. doi: 10.1128/mcb.3.10.1824. [DOI] [PMC free article] [PubMed] [Google Scholar]
  246. Jonas V., Lin C. R., Kawashima E., Semon D., Swanson L. W., Mermod J. J., Evans R. M., Rosenfeld M. G. Alternative RNA processing events in human calcitonin/calcitonin gene-related peptide gene expression. Proc Natl Acad Sci U S A. 1985 Apr;82(7):1994–1998. doi: 10.1073/pnas.82.7.1994. [DOI] [PMC free article] [PubMed] [Google Scholar]
  247. Jones D., Russnak R. H., Kay R. J., Candido E. P. Structure, expression, and evolution of a heat shock gene locus in Caenorhabditis elegans that is flanked by repetitive elements. J Biol Chem. 1986 Sep 15;261(26):12006–12015. [PubMed] [Google Scholar]
  248. Jones W. K., Yu-Lee L. Y., Clift S. M., Brown T. L., Rosen J. M. The rat casein multigene family. Fine structure and evolution of the beta-casein gene. J Biol Chem. 1985 Jun 10;260(11):7042–7050. [PubMed] [Google Scholar]
  249. Julien J. P., Grosveld F., Yazdanbaksh K., Flavell D., Meijer D., Mushynski W. The structure of a human neurofilament gene (NF-L): a unique exon-intron organization in the intermediate filament gene family. Biochim Biophys Acta. 1987 Jun 6;909(1):10–20. doi: 10.1016/0167-4781(87)90041-8. [DOI] [PubMed] [Google Scholar]
  250. Jung A., Sippel A. E., Grez M., Schütz G. Exons encode functional and structural units of chicken lysozyme. Proc Natl Acad Sci U S A. 1980 Oct;77(10):5759–5763. doi: 10.1073/pnas.77.10.5759. [DOI] [PMC free article] [PubMed] [Google Scholar]
  251. Kalb V. F., Glasser S., King D., Lingrel J. B. A cluster of repetitive elements within a 700 base pair region in the mouse genome. Nucleic Acids Res. 1983 Apr 11;11(7):2177–2184. doi: 10.1093/nar/11.7.2177. [DOI] [PMC free article] [PubMed] [Google Scholar]
  252. Karathanasis S. K., Zannis V. I., Breslow J. L. Isolation and characterization of the human apolipoprotein A-I gene. Proc Natl Acad Sci U S A. 1983 Oct;80(20):6147–6151. doi: 10.1073/pnas.80.20.6147. [DOI] [PMC free article] [PubMed] [Google Scholar]
  253. Karin M., Richards R. I. Human metallothionein genes--primary structure of the metallothionein-II gene and a related processed gene. Nature. 1982 Oct 28;299(5886):797–802. doi: 10.1038/299797a0. [DOI] [PubMed] [Google Scholar]
  254. Karlik C. C., Coutu M. D., Fyrberg E. A. A nonsense mutation within the act88F actin gene disrupts myofibril formation in Drosophila indirect flight muscles. Cell. 1984 Oct;38(3):711–719. doi: 10.1016/0092-8674(84)90266-6. [DOI] [PubMed] [Google Scholar]
  255. Karlin-Neumann G. A., Kohorn B. D., Thornber J. P., Tobin E. M. A chlorophyll a/b-protein encoded by a gene containing an intron with characteristics of a transposable element. J Mol Appl Genet. 1985;3(1):45–61. [PubMed] [Google Scholar]
  256. Karn J., Brenner S., Barnett L. Protein structural domains in the Caenorhabditis elegans unc-54 myosin heavy chain gene are not separated by introns. Proc Natl Acad Sci U S A. 1983 Jul;80(14):4253–4257. doi: 10.1073/pnas.80.14.4253. [DOI] [PMC free article] [PubMed] [Google Scholar]
  257. Kassis J. A., Poole S. J., Wright D. K., O'Farrell P. H. Sequence conservation in the protein coding and intron regions of the engrailed transcription unit. EMBO J. 1986 Dec 20;5(13):3583–3589. doi: 10.1002/j.1460-2075.1986.tb04686.x. [DOI] [PMC free article] [PubMed] [Google Scholar]
  258. Kataoka T., Nikaido T., Miyata T., Moriwaki K., Honjo T. The nucleotide sequences of rearranged and germline immunoglobulin VH genes of a mouse myeloma MC101 and evolution of VH genes in mouse. J Biol Chem. 1982 Jan 10;257(1):277–285. [PubMed] [Google Scholar]
  259. Katinakis P., Verma D. P. Nodulin-24 gene of soybean codes for a peptide of the peribacteroid membrane and was generated by tandem duplication of a sequence resembling an insertion element. Proc Natl Acad Sci U S A. 1985 Jun;82(12):4157–4161. doi: 10.1073/pnas.82.12.4157. [DOI] [PMC free article] [PubMed] [Google Scholar]
  260. Kato N., Harada F. New U1 RNA species found in Friend SFFV (spleen focus forming virus)-transformed mouse cells. J Biol Chem. 1985 Jun 25;260(12):7775–7782. [PubMed] [Google Scholar]
  261. Katoh K., Sawai S., Ueno K., Kondoh H. Complete nucleotide sequence and exon-intron boundaries of the 5' non-coding region of the mouse N-myc gene. Nucleic Acids Res. 1988 Apr 25;16(8):3589–3589. doi: 10.1093/nar/16.8.3589. [DOI] [PMC free article] [PubMed] [Google Scholar]
  262. Katz A., Kahana C. Isolation and characterization of the mouse ornithine decarboxylase gene. J Biol Chem. 1988 Jun 5;263(16):7604–7609. [PubMed] [Google Scholar]
  263. Kawajiri K., Watanabe J., Gotoh O., Tagashira Y., Sogawa K., Fujii-Kuriyama Y. Structure and drug inducibility of the human cytochrome P-450c gene. Eur J Biochem. 1986 Sep 1;159(2):219–225. doi: 10.1111/j.1432-1033.1986.tb09857.x. [DOI] [PubMed] [Google Scholar]
  264. Kawakami T., Takahashi N., Honjo T. Complete nucleotide sequence of mouse immunoglobulin mu gene and comparison with other immunoglobulin heavy chain genes. Nucleic Acids Res. 1980 Sep 11;8(17):3933–3945. doi: 10.1093/nar/8.17.3933. [DOI] [PMC free article] [PubMed] [Google Scholar]
  265. Kay R. J., Russnak R. H., Jones D., Mathias C., Candido E. P. Expression of intron-containing C. elegans heat shock genes in mouse cells demonstrates divergence of 3' splice site recognition sequences between nematodes and vertebrates, and an inhibitory effect of heat shock on the mammalian splicing apparatus. Nucleic Acids Res. 1987 May 11;15(9):3723–3741. doi: 10.1093/nar/15.9.3723. [DOI] [PMC free article] [PubMed] [Google Scholar]
  266. Kazazian H. H., Jr, Orkin S. H., Antonarakis S. E., Sexton J. P., Boehm C. D., Goff S. C., Waber P. G. Molecular characterization of seven beta-thalassemia mutations in Asian Indians. EMBO J. 1984 Mar;3(3):593–596. doi: 10.1002/j.1460-2075.1984.tb01853.x. [DOI] [PMC free article] [PubMed] [Google Scholar]
  267. Keil G. M., Ebeling-Keil A., Koszinowski U. H. Sequence and structural organization of murine cytomegalovirus immediate-early gene 1. J Virol. 1987 Jun;61(6):1901–1908. doi: 10.1128/jvi.61.6.1901-1908.1987. [DOI] [PMC free article] [PubMed] [Google Scholar]
  268. Keil M., Sanchez-Serrano J., Schell J., Willmitzer L. Primary structure of a proteinase inhibitor II gene from potato (Solanum tuberosum). Nucleic Acids Res. 1986 Jul 25;14(14):5641–5650. doi: 10.1093/nar/14.14.5641. [DOI] [PMC free article] [PubMed] [Google Scholar]
  269. Kim H. S., Maeda N. Structures of two HaeIII-type genes in the human salivary proline-rich protein multigene family. J Biol Chem. 1986 May 25;261(15):6712–6718. [PubMed] [Google Scholar]
  270. Kimmel A. R., Firtel R. A. Intervening sequences in a Dictyostelium gene that encodes a low abundance class mRNA. Nucleic Acids Res. 1980 Dec 11;8(23):5599–5610. doi: 10.1093/nar/8.23.5599. [DOI] [PMC free article] [PubMed] [Google Scholar]
  271. King C. R., Piatigorsky J. Alternative RNA splicing of the murine alpha A-crystallin gene: protein-coding information within an intron. Cell. 1983 Mar;32(3):707–712. doi: 10.1016/0092-8674(83)90056-9. [DOI] [PubMed] [Google Scholar]
  272. Kiss I., Deák F., Mestrić S., Delius H., Soos J., Dékány K., Argraves W. S., Sparks K. J., Goetinck P. F. Structure of the chicken link protein gene: exons correlate with the protein domains. Proc Natl Acad Sci U S A. 1987 Sep;84(18):6399–6403. doi: 10.1073/pnas.84.18.6399. [DOI] [PMC free article] [PubMed] [Google Scholar]
  273. Kiss T., Antal M., Hegyi H., Solymosy F. Plant small nuclear RNAs. IV. The structure of U1 RNA from Chlorella saccharophila: a phylogenetic support, in terms of RNA structure, for the probable interaction between U1 and U2 and RNPs during the splicing of pre-mRNA. Nucleic Acids Res. 1988 Mar 25;16(6):2734–2734. doi: 10.1093/nar/16.6.2734. [DOI] [PMC free article] [PubMed] [Google Scholar]
  274. Kitamura N., Kitagawa H., Fukushima D., Takagaki Y., Miyata T., Nakanishi S. Structural organization of the human kininogen gene and a model for its evolution. J Biol Chem. 1985 Jul 15;260(14):8610–8617. [PubMed] [Google Scholar]
  275. Klee H. J., Muskopf Y. M., Gasser C. S. Cloning of an Arabidopsis thaliana gene encoding 5-enolpyruvylshikimate-3-phosphate synthase: sequence analysis and manipulation to obtain glyphosate-tolerant plants. Mol Gen Genet. 1987 Dec;210(3):437–442. doi: 10.1007/BF00327194. [DOI] [PubMed] [Google Scholar]
  276. Kleinsek D. A., Beattie W. G., Tsai M. J., O'Malley B. W. Molecular cloning of a steroid-regulated 108K heat shock protein gene from hen oviduct. Nucleic Acids Res. 1986 Dec 22;14(24):10053–10069. doi: 10.1093/nar/14.24.10053. [DOI] [PMC free article] [PubMed] [Google Scholar]
  277. Klobeck H. G., Meindl A., Combriato G., Solomon A., Zachau H. G. Human immunoglobulin kappa light chain genes of subgroups II and III. Nucleic Acids Res. 1985 Sep 25;13(18):6499–6513. doi: 10.1093/nar/13.18.6499. [DOI] [PMC free article] [PubMed] [Google Scholar]
  278. Knoll B. J., Rothblum K. N., Longley M. Nucleotide sequence of the human placental alkaline phosphatase gene. Evolution of the 5' flanking region by deletion/substitution. J Biol Chem. 1988 Aug 25;263(24):12020–12027. [PubMed] [Google Scholar]
  279. Knöchel W., Beck J., Meyerhof W. Nucleotide sequence of the Xenopus tropicalis larval beta globin gene. Nucleic Acids Res. 1987 Dec 10;15(23):10062–10062. doi: 10.1093/nar/15.23.10062. [DOI] [PMC free article] [PubMed] [Google Scholar]
  280. Knöchel W., Pfanne K., Beck J., Meyerhof W. Nucleotide sequence of a larval alpha globin gene from Xenopus tropicalis. Nucleic Acids Res. 1988 Feb 25;16(4):1625–1625. doi: 10.1093/nar/16.4.1625. [DOI] [PMC free article] [PubMed] [Google Scholar]
  281. Kobayashi K., Kaneda N., Ichinose H., Kishi F., Nakazawa A., Kurosawa Y., Fujita K., Nagatsu T. Structure of the human tyrosine hydroxylase gene: alternative splicing from a single gene accounts for generation of four mRNA types. J Biochem. 1988 Jun;103(6):907–912. doi: 10.1093/oxfordjournals.jbchem.a122386. [DOI] [PubMed] [Google Scholar]
  282. Koch N., Lauer W., Habicht J., Dobberstein B. Primary structure of the gene for the murine Ia antigen-associated invariant chains (Ii). An alternatively spliced exon encodes a cysteine-rich domain highly homologous to a repetitive sequence of thyroglobulin. EMBO J. 1987 Jun;6(6):1677–1683. doi: 10.1002/j.1460-2075.1987.tb02417.x. [DOI] [PMC free article] [PubMed] [Google Scholar]
  283. Kohno K., Sullivan M., Yamada Y. Structure of the promoter of the rat type II procollagen gene. J Biol Chem. 1985 Apr 10;260(7):4441–4447. [PubMed] [Google Scholar]
  284. Konkel D. A., Maizel J. V., Jr, Leder P. The evolution and sequence comparison of two recently diverged mouse chromosomal beta--globin genes. Cell. 1979 Nov;18(3):865–873. doi: 10.1016/0092-8674(79)90138-7. [DOI] [PubMed] [Google Scholar]
  285. Kopito R. R., Andersson M., Lodish H. F. Structure and organization of the murine band 3 gene. J Biol Chem. 1987 Jun 15;262(17):8035–8040. [PubMed] [Google Scholar]
  286. Kost T. A., Theodorakis N., Hughes S. H. The nucleotide sequence of the chick cytoplasmic beta-actin gene. Nucleic Acids Res. 1983 Dec 10;11(23):8287–8301. doi: 10.1093/nar/11.23.8287. [DOI] [PMC free article] [PubMed] [Google Scholar]
  287. Kramer J. M., Cox G. N., Hirsh D. Comparisons of the complete sequences of two collagen genes from Caenorhabditis elegans. Cell. 1982 Sep;30(2):599–606. doi: 10.1016/0092-8674(82)90256-2. [DOI] [PubMed] [Google Scholar]
  288. Krawetz S. A., Connor W., Dixon G. H. Bovine protamine genes contain a single intron. The structures of the two alleles. J Biol Chem. 1988 Jan 5;263(1):321–326. [PubMed] [Google Scholar]
  289. Kreader C. A., Heckman J. E. Isolation and characterization of a Neurospora crassa ribosomal protein gene homologous to CYH2 of yeast. Nucleic Acids Res. 1987 Nov 11;15(21):9027–9042. doi: 10.1093/nar/15.21.9027. [DOI] [PMC free article] [PubMed] [Google Scholar]
  290. Kretzner L., Rymond B. C., Rosbash M. S. cerevisiae U1 RNA is large and has limited primary sequence homology to metazoan U1 snRNA. Cell. 1987 Aug 14;50(4):593–602. doi: 10.1016/0092-8674(87)90032-8. [DOI] [PubMed] [Google Scholar]
  291. Krieg T. M., Schafer M. P., Cheng C. K., Filpula D., Flaherty P., Steinert P. M., Roop D. R. Organization of a type I keratin gene. Evidence for evolution of intermediate filaments from a common ancestral gene. J Biol Chem. 1985 May 25;260(10):5867–5870. [PubMed] [Google Scholar]
  292. Kropp K., Gulick J., Robbins J. A canonical sequence organization at the 5'-end of the myosin heavy chain genes. J Biol Chem. 1986 May 15;261(14):6613–6618. [PubMed] [Google Scholar]
  293. Kudo J., Chao L. Y., Narni F., Saunders G. F. Structure of the human gene encoding the invariant gamma-chain of class II histocompatibility antigens. Nucleic Acids Res. 1985 Dec 20;13(24):8827–8841. doi: 10.1093/nar/13.24.8827. [DOI] [PMC free article] [PubMed] [Google Scholar]
  294. Kuiper M. T., Akins R. A., Holtrop M., de Vries H., Lambowitz A. M. Isolation and analysis of the Neurospora crassa Cyt-21 gene. A nuclear gene encoding a mitochondrial ribosomal protein. J Biol Chem. 1988 Feb 25;263(6):2840–2847. [PubMed] [Google Scholar]
  295. Kwan S. P., Max E. E., Seidman J. G., Leder P., Scharff M. D. Two kappa immunoglobulin genes are expressed in the myeloma S107. Cell. 1981 Oct;26(1 Pt 1):57–66. doi: 10.1016/0092-8674(81)90033-7. [DOI] [PubMed] [Google Scholar]
  296. Kwok S. C., Chan S. J., Steiner D. F. Cloning and nucleotide sequence analysis of the dog insulin gene. Coded amino acid sequence of canine preproinsulin predicts an additional C-peptide fragment. J Biol Chem. 1983 Feb 25;258(4):2357–2363. [PubMed] [Google Scholar]
  297. Laird J. E., Jack L., Hall L., Boulton A. P., Parker D., Craig R. K. Structure and expression of the guinea-pig alpha-lactalbumin gene. Biochem J. 1988 Aug 15;254(1):85–94. doi: 10.1042/bj2540085. [DOI] [PMC free article] [PubMed] [Google Scholar]
  298. Lang G., Wotton D., Owen M. J., Sewell W. A., Brown M. H., Mason D. Y., Crumpton M. J., Kioussis D. The structure of the human CD2 gene and its expression in transgenic mice. EMBO J. 1988 Jun;7(6):1675–1682. doi: 10.1002/j.1460-2075.1988.tb02995.x. [DOI] [PMC free article] [PubMed] [Google Scholar]
  299. Langford C., Nellen W., Niessing J., Gallwitz D. Yeast is unable to excise foreign intervening sequences from hybrid gene transcripts. Proc Natl Acad Sci U S A. 1983 Mar;80(6):1496–1500. doi: 10.1073/pnas.80.6.1496. [DOI] [PMC free article] [PubMed] [Google Scholar]
  300. Lapoumeroulie C., Acuto S., Rouabhi F., Labie D., Krishnamoorthy R., Bank A. Expression of a beta thalassemia gene with abnormal splicing. Nucleic Acids Res. 1987 Oct 26;15(20):8195–8204. doi: 10.1093/nar/15.20.8195. [DOI] [PMC free article] [PubMed] [Google Scholar]
  301. Lapoumeroulie C., Pagnier J., Bank A., Labie D., Krishnamoorthy R. Beta thalassemia due to a novel mutation in IVS 1 sequence donor site consensus sequence creating a restriction site. Biochem Biophys Res Commun. 1986 Sep 14;139(2):709–713. doi: 10.1016/s0006-291x(86)80048-1. [DOI] [PubMed] [Google Scholar]
  302. Larhammar D., Hammerling U., Rask L., Peterson P. A. Sequence of gene and cDNA encoding murine major histocompatibility complex class II gene A beta 2. J Biol Chem. 1985 Nov 15;260(26):14111–14119. [PubMed] [Google Scholar]
  303. Latchman D. S. A potential role for U1 RNA genes in gene duplication and conversion events. FEBS Lett. 1988 Aug 15;236(1):5–8. doi: 10.1016/0014-5793(88)80274-6. [DOI] [PubMed] [Google Scholar]
  304. Lauer S. J., Walker D., Elshourbagy N. A., Reardon C. A., Levy-Wilson B., Taylor J. M. Two copies of the human apolipoprotein C-I gene are linked closely to the apolipoprotein E gene. J Biol Chem. 1988 May 25;263(15):7277–7286. [PubMed] [Google Scholar]
  305. Laughon A., Boulet A. M., Bermingham J. R., Jr, Laymon R. A., Scott M. P. Structure of transcripts from the homeotic Antennapedia gene of Drosophila melanogaster: two promoters control the major protein-coding region. Mol Cell Biol. 1986 Dec;6(12):4676–4689. doi: 10.1128/mcb.6.12.4676. [DOI] [PMC free article] [PubMed] [Google Scholar]
  306. Lavu S., Reddy E. P. Structural organization and nucleotide sequence of mouse c-myb oncogene: activation in ABPL tumors is due to viral integration in an intron which results in the deletion of the 5' coding sequences. Nucleic Acids Res. 1986 Jul 11;14(13):5309–5320. doi: 10.1093/nar/14.13.5309. [DOI] [PMC free article] [PubMed] [Google Scholar]
  307. Lawn R. M., Efstratiadis A., O'Connell C., Maniatis T. The nucleotide sequence of the human beta-globin gene. Cell. 1980 Oct;21(3):647–651. doi: 10.1016/0092-8674(80)90428-6. [DOI] [PubMed] [Google Scholar]
  308. Lawrance S. K., Das H. K., Pan J., Weissman S. M. The genomic organisation and nucleotide sequence of the HLA-SB(DP) alpha gene. Nucleic Acids Res. 1985 Oct 25;13(20):7515–7528. doi: 10.1093/nar/13.20.7515. [DOI] [PMC free article] [PubMed] [Google Scholar]
  309. Lazar E., Jacob M., Krol A., Branlant C. Accessibility of U1 RNA to base pairing with a single-stranded DNA fragment mimicking the intron extremities at the splice junction. Nucleic Acids Res. 1982 Feb 25;10(4):1193–1201. doi: 10.1093/nar/10.4.1193. [DOI] [PMC free article] [PubMed] [Google Scholar]
  310. Leder A., Miller H. I., Hamer D. H., Seidman J. G., Norman B., Sullivan M., Leder P. Comparison of cloned mouse alpha- and beta-globin genes: conservation of intervening sequence locations and extragenic homology. Proc Natl Acad Sci U S A. 1978 Dec;75(12):6187–6191. doi: 10.1073/pnas.75.12.6187. [DOI] [PMC free article] [PubMed] [Google Scholar]
  311. Leder A., Weir L., Leder P. Characterization, expression, and evolution of the mouse embryonic zeta-globin gene. Mol Cell Biol. 1985 May;5(5):1025–1033. doi: 10.1128/mcb.5.5.1025. [DOI] [PMC free article] [PubMed] [Google Scholar]
  312. Lee C. P., Kao M. C., French B. A., Putney S. D., Chang S. H. The rabbit muscle phosphofructokinase gene. Implications for protein structure, function, and tissue specificity. J Biol Chem. 1987 Mar 25;262(9):4195–4199. [PubMed] [Google Scholar]
  313. Lee J. S., Trowsdale J., Travers P. J., Carey J., Grosveld F., Jenkins J., Bodmer W. F. Sequence of an HLA-DR alpha-chain cDNA clone and intron-exon organization of the corresponding gene. Nature. 1982 Oct 21;299(5885):750–752. doi: 10.1038/299750a0. [DOI] [PubMed] [Google Scholar]
  314. Lee M. G., Loomis C., Cowan N. J. Sequence of an expressed human beta-tubulin gene containing ten Alu family members. Nucleic Acids Res. 1984 Jul 25;12(14):5823–5836. doi: 10.1093/nar/12.14.5823. [DOI] [PMC free article] [PubMed] [Google Scholar]
  315. Leer R. J., van Raamsdonk-Duin M. M., Hagendoorn M. J., Mager W. H., Planta R. J. Structural comparison of yeast ribosomal protein genes. Nucleic Acids Res. 1984 Sep 11;12(17):6685–6700. doi: 10.1093/nar/12.17.6685. [DOI] [PMC free article] [PubMed] [Google Scholar]
  316. Leer R. J., van Raamsdonk-Duin M. M., Kraakman P., Mager W. H., Planta R. J. The genes for yeast ribosomal proteins S24 and L46 are adjacent and divergently transcribed. Nucleic Acids Res. 1985 Feb 11;13(3):701–709. doi: 10.1093/nar/13.3.701. [DOI] [PMC free article] [PubMed] [Google Scholar]
  317. Leer R. J., van Raamsdonk-Duin M. M., Molenaar C. M., Witsenboer H. M., Mager W. H., Planta R. J. Yeast contains two functional genes coding for ribosomal protein S10. Nucleic Acids Res. 1985 Jul 25;13(14):5027–5039. doi: 10.1093/nar/13.14.5027. [DOI] [PMC free article] [PubMed] [Google Scholar]
  318. Lei K. J., Liu T., Zon G., Soravia E., Liu T. Y., Goldman N. D. Genomic DNA sequence for human C-reactive protein. J Biol Chem. 1985 Oct 25;260(24):13377–13383. [PubMed] [Google Scholar]
  319. Leibold E. A., Munro H. N. Characterization and evolution of the expressed rat ferritin light subunit gene and its pseudogene family. Conservation of sequences within noncoding regions of ferritin genes. J Biol Chem. 1987 May 25;262(15):7335–7341. [PubMed] [Google Scholar]
  320. Lemischka I., Sharp P. A. The sequences of an expressed rat alpha-tubulin gene and a pseudogene with an inserted repetitive element. Nature. 1982 Nov 25;300(5890):330–335. doi: 10.1038/300330a0. [DOI] [PubMed] [Google Scholar]
  321. Lemke G., Lamar E., Patterson J. Isolation and analysis of the gene encoding peripheral myelin protein zero. Neuron. 1988 Mar;1(1):73–83. doi: 10.1016/0896-6273(88)90211-5. [DOI] [PubMed] [Google Scholar]
  322. Leonard W. J., Depper J. M., Kanehisa M., Krönke M., Peffer N. J., Svetlik P. B., Sullivan M., Greene W. C. Structure of the human interleukin-2 receptor gene. Science. 1985 Nov 8;230(4726):633–639. doi: 10.1126/science.2996141. [DOI] [PubMed] [Google Scholar]
  323. Lerner M. R., Boyle J. A., Mount S. M., Wolin S. L., Steitz J. A. Are snRNPs involved in splicing? Nature. 1980 Jan 10;283(5743):220–224. doi: 10.1038/283220a0. [DOI] [PubMed] [Google Scholar]
  324. Leung J. O., Holland E. C., Drickamer K. Characterization of the gene encoding the major rat liver asialoglycoprotein receptor. J Biol Chem. 1985 Oct 15;260(23):12523–12527. [PubMed] [Google Scholar]
  325. Levy E., Liem R. K., D'Eustachio P., Cowan N. J. Structure and evolutionary origin of the gene encoding mouse NF-M, the middle-molecular-mass neurofilament protein. Eur J Biochem. 1987 Jul 1;166(1):71–77. doi: 10.1111/j.1432-1033.1987.tb13485.x. [DOI] [PubMed] [Google Scholar]
  326. Lewis S. A., Cowan N. J. Anomalous placement of introns in a member of the intermediate filament multigene family: an evolutionary conundrum. Mol Cell Biol. 1986 May;6(5):1529–1534. doi: 10.1128/mcb.6.5.1529. [DOI] [PMC free article] [PubMed] [Google Scholar]
  327. Limbach K. J., Wu R. Characterization of a mouse somatic cytochrome c gene and three cytochrome c pseudogenes. Nucleic Acids Res. 1985 Jan 25;13(2):617–630. doi: 10.1093/nar/13.2.617. [DOI] [PMC free article] [PubMed] [Google Scholar]
  328. Lin R. J., Newman A. J., Cheng S. C., Abelson J. Yeast mRNA splicing in vitro. J Biol Chem. 1985 Nov 25;260(27):14780–14792. [PubMed] [Google Scholar]
  329. Lipshitz H. D., Peattie D. A., Hogness D. S. Novel transcripts from the Ultrabithorax domain of the bithorax complex. Genes Dev. 1987 May;1(3):307–322. doi: 10.1101/gad.1.3.307. [DOI] [PubMed] [Google Scholar]
  330. Litman G. W., Murphy K., Berger L., Litman R., Hinds K., Erickson B. W. Complete nucleotide sequences of three VH genes in Caiman, a phylogenetically ancient reptile: evolutionary diversification in coding segments and variation in the structure and organization of recombination elements. Proc Natl Acad Sci U S A. 1985 Feb;82(3):844–848. doi: 10.1073/pnas.82.3.844. [DOI] [PMC free article] [PubMed] [Google Scholar]
  331. Lok S., Tsui L. C., Shinohara T., Piatigorsky J., Gold R., Breitman M. Analysis of the mouse gamma-crystallin gene family: assignment of multiple cDNAs to discrete genomic sequences and characterization of a representative gene. Nucleic Acids Res. 1984 Jun 11;12(11):4517–4529. doi: 10.1093/nar/12.11.4517. [DOI] [PMC free article] [PubMed] [Google Scholar]
  332. Lomedico P., Rosenthal N., Efstratidadis A., Gilbert W., Kolodner R., Tizard R. The structure and evolution of the two nonallelic rat preproinsulin genes. Cell. 1979 Oct;18(2):545–558. doi: 10.1016/0092-8674(79)90071-0. [DOI] [PubMed] [Google Scholar]
  333. Lonberg N., Gilbert W. Intron/exon structure of the chicken pyruvate kinase gene. Cell. 1985 Jan;40(1):81–90. doi: 10.1016/0092-8674(85)90311-3. [DOI] [PubMed] [Google Scholar]
  334. Long G. L., Chandra T., Woo S. L., Davie E. W., Kurachi K. Complete sequence of the cDNA for human alpha 1-antitrypsin and the gene for the S variant. Biochemistry. 1984 Oct 9;23(21):4828–4837. doi: 10.1021/bi00316a003. [DOI] [PubMed] [Google Scholar]
  335. Loreni F., Ruberti I., Bozzoni I., Pierandrei-Amaldi P., Amaldi F. Nucleotide sequence of the L1 ribosomal protein gene of Xenopus laevis: remarkable sequence homology among introns. EMBO J. 1985 Dec 16;4(13A):3483–3488. doi: 10.1002/j.1460-2075.1985.tb04107.x. [DOI] [PMC free article] [PubMed] [Google Scholar]
  336. Lund E. Heterogeneity of human U1 snRNAs. Nucleic Acids Res. 1988 Jul 11;16(13):5813–5826. doi: 10.1093/nar/16.13.5813. [DOI] [PMC free article] [PubMed] [Google Scholar]
  337. Luskey K. L. Conservation of promoter sequence but not complex intron splicing pattern in human and hamster genes for 3-hydroxy-3-methylglutaryl coenzyme A reductase. Mol Cell Biol. 1987 May;7(5):1881–1893. doi: 10.1128/mcb.7.5.1881. [DOI] [PMC free article] [PubMed] [Google Scholar]
  338. Lycett G. W., Croy R. R., Shirsat A. H., Boulter D. The complete nucleotide sequence of a legumin gene from pea (Pisum sativum L.). Nucleic Acids Res. 1984 Jun 11;12(11):4493–4506. doi: 10.1093/nar/12.11.4493. [DOI] [PMC free article] [PubMed] [Google Scholar]
  339. Lévi-Strauss M., Carroll M. C., Steinmetz M., Meo T. A previously undetected MHC gene with an unusual periodic structure. Science. 1988 Apr 8;240(4849):201–204. doi: 10.1126/science.3353717. [DOI] [PubMed] [Google Scholar]
  340. Maguire D. J., Day A. R., Borthwick I. A., Srivastava G., Wigley P. L., May B. K., Elliott W. H. Nucleotide sequence of the chicken 5-aminolevulinate synthase gene. Nucleic Acids Res. 1986 Feb 11;14(3):1379–1391. doi: 10.1093/nar/14.3.1379. [DOI] [PMC free article] [PubMed] [Google Scholar]
  341. Malissen M., Hunkapiller T., Hood L. Nucleotide sequence of a light chain gene of the mouse I-A subregion: A beta d. Science. 1983 Aug 19;221(4612):750–754. doi: 10.1126/science.6410508. [DOI] [PubMed] [Google Scholar]
  342. Malissen M., Malissen B., Jordan B. R. Exon/intron organization and complete nucleotide sequence of an HLA gene. Proc Natl Acad Sci U S A. 1982 Feb;79(3):893–897. doi: 10.1073/pnas.79.3.893. [DOI] [PMC free article] [PubMed] [Google Scholar]
  343. Mann R., Baltimore D. Varying the position of a retrovirus packaging sequence results in the encapsidation of both unspliced and spliced RNAs. J Virol. 1985 May;54(2):401–407. doi: 10.1128/jvi.54.2.401-407.1985. [DOI] [PMC free article] [PubMed] [Google Scholar]
  344. Marazziti D., Eggertsen G., Fey G. H., Stanley K. K. Relationships between the gene and protein structure in human complement component C9. Biochemistry. 1988 Aug 23;27(17):6529–6534. doi: 10.1021/bi00417a050. [DOI] [PubMed] [Google Scholar]
  345. Marche P. N., Tykocinski M. L., Max E. E., Kindt T. J. Structure of a functional rabbit class I MHC gene: similarity to human class I genes. Immunogenetics. 1985;21(1):71–82. doi: 10.1007/BF00372243. [DOI] [PubMed] [Google Scholar]
  346. Marchionni M., Gilbert W. The triosephosphate isomerase gene from maize: introns antedate the plant-animal divergence. Cell. 1986 Jul 4;46(1):133–141. doi: 10.1016/0092-8674(86)90867-6. [DOI] [PubMed] [Google Scholar]
  347. Marchuk D., McCrohon S., Fuchs E. Complete sequence of a gene encoding a human type I keratin: sequences homologous to enhancer elements in the regulatory region of the gene. Proc Natl Acad Sci U S A. 1985 Mar;82(6):1609–1613. doi: 10.1073/pnas.82.6.1609. [DOI] [PMC free article] [PubMed] [Google Scholar]
  348. Marco Y. A., Thanh V. H., Tumer N. E., Scallon B. J., Nielsen N. C. Cloning and structural analysis of DNA encoding an A2B1a subunit of glycinin. J Biol Chem. 1984 Nov 10;259(21):13436–13441. [PubMed] [Google Scholar]
  349. Marks J., Shaw J. P., Shen C. K. Sequence organization and genomic complexity of primate theta 1 globin gene, a novel alpha-globin-like gene. Nature. 1986 Jun 19;321(6072):785–788. doi: 10.1038/321785a0. [DOI] [PubMed] [Google Scholar]
  350. Martin C. H., Mayeda C. A., Meyerowitz E. M. Evolution and expression of the Sgs-3 glue gene of Drosophila. J Mol Biol. 1988 May 20;201(2):273–287. doi: 10.1016/0022-2836(88)90138-6. [DOI] [PubMed] [Google Scholar]
  351. Mason A. J., Evans B. A., Cox D. R., Shine J., Richards R. I. Structure of mouse kallikrein gene family suggests a role in specific processing of biologically active peptides. Nature. 1983 May 26;303(5915):300–307. doi: 10.1038/303300a0. [DOI] [PubMed] [Google Scholar]
  352. Matthyssens G., Rabbitts T. H. Structure and multiplicity of genes for the human immunoglobulin heavy chain variable region. Proc Natl Acad Sci U S A. 1980 Nov;77(11):6561–6565. doi: 10.1073/pnas.77.11.6561. [DOI] [PMC free article] [PubMed] [Google Scholar]
  353. Mauro V. P., Nguyen T., Katinakis P., Verma D. P. Primary structure of the soybean nodulin-23 gene and potential regulatory elements in the 5'-flanking regions of nodulin and leghemoglobin genes. Nucleic Acids Res. 1985 Jan 11;13(1):239–249. doi: 10.1093/nar/13.1.239. [DOI] [PMC free article] [PubMed] [Google Scholar]
  354. Max E. E., Maizel J. V., Jr, Leder P. The nucleotide sequence of a 5.5-kilobase DNA segment containing the mouse kappa immunoglobulin J and C region genes. J Biol Chem. 1981 May 25;256(10):5116–5120. [PubMed] [Google Scholar]
  355. Max E. E., Seidman J. G., Leder P. Sequences of five potential recombination sites encoded close to an immunoglobulin kappa constant region gene. Proc Natl Acad Sci U S A. 1979 Jul;76(7):3450–3454. doi: 10.1073/pnas.76.7.3450. [DOI] [PMC free article] [PubMed] [Google Scholar]
  356. Mayo K. E., Cerelli G. M., Lebo R. V., Bruce B. D., Rosenfeld M. G., Evans R. M. Gene encoding human growth hormone-releasing factor precursor: structure, sequence, and chromosomal assignment. Proc Natl Acad Sci U S A. 1985 Jan;82(1):63–67. doi: 10.1073/pnas.82.1.63. [DOI] [PMC free article] [PubMed] [Google Scholar]
  357. Mazur B. J., Chui C. F. Sequence of a genomic DNA clone for the small subunit of ribulose bis-phosphate carboxylase-oxygenase from tobacco. Nucleic Acids Res. 1985 Apr 11;13(7):2373–2386. doi: 10.1093/nar/13.7.2373. [DOI] [PMC free article] [PubMed] [Google Scholar]
  358. McDonald J. D., Lin F. K., Goldwasser E. Cloning, sequencing, and evolutionary analysis of the mouse erythropoietin gene. Mol Cell Biol. 1986 Mar;6(3):842–848. doi: 10.1128/mcb.6.3.842. [DOI] [PMC free article] [PubMed] [Google Scholar]
  359. McGuire K. L., Duncan W. R., Tucker P. W. Phylogenetic conservation of immunoglobulin heavy chains: direct comparison of hamster and mouse Cmu genes. Nucleic Acids Res. 1985 Aug 12;13(15):5611–5628. doi: 10.1093/nar/13.15.5611. [DOI] [PMC free article] [PubMed] [Google Scholar]
  360. McKnight G. L., Kato H., Upshall A., Parker M. D., Saari G., O'Hara P. J. Identification and molecular analysis of a third Aspergillus nidulans alcohol dehydrogenase gene. EMBO J. 1985 Aug;4(8):2093–2099. doi: 10.1002/j.1460-2075.1985.tb03897.x. [DOI] [PMC free article] [PubMed] [Google Scholar]
  361. McKnight G. L., O'Hara P. J., Parker M. L. Nucleotide sequence of the triosephosphate isomerase gene from Aspergillus nidulans: implications for a differential loss of introns. Cell. 1986 Jul 4;46(1):143–147. doi: 10.1016/0092-8674(86)90868-8. [DOI] [PubMed] [Google Scholar]
  362. Meeker T. C., Nagarajan L., ar-Rushdi A., Rovera G., Huebner K., Croce C. M. Characterization of the human PIM-1 gene: a putative proto-oncogene coding for a tissue specific member of the protein kinase family. Oncogene Res. 1987 Jun;1(1):87–101. [PubMed] [Google Scholar]
  363. Michelson A. M., Blake C. C., Evans S. T., Orkin S. H. Structure of the human phosphoglycerate kinase gene and the intron-mediated evolution and dispersal of the nucleotide-binding domain. Proc Natl Acad Sci U S A. 1985 Oct;82(20):6965–6969. doi: 10.1073/pnas.82.20.6965. [DOI] [PMC free article] [PubMed] [Google Scholar]
  364. Michelson A. M., Orkin S. H. Boundaries of gene conversion within the duplicated human alpha-globin genes. Concerted evolution by segmental recombination. J Biol Chem. 1983 Dec 25;258(24):15245–15254. [PubMed] [Google Scholar]
  365. Mignery G. A., Pikaard C. S., Park W. D. Molecular characterization of the patatin multigene family of potato. Gene. 1988;62(1):27–44. doi: 10.1016/0378-1119(88)90577-x. [DOI] [PubMed] [Google Scholar]
  366. Milstein C. P., Deverson E. V., Rabbitts T. H. The sequence of the human immunoglobulin mu-delta intron reveals possible vestigial switch segments. Nucleic Acids Res. 1984 Aug 24;12(16):6523–6535. doi: 10.1093/nar/12.16.6523. [DOI] [PMC free article] [PubMed] [Google Scholar]
  367. Minghetti P. P., Cancela L., Fujisawa Y., Theofan G., Norman A. W. Molecular structure of the chicken vitamin D-induced calbindin-D28K gene reveals eleven exons, six Ca2+-binding domains, and numerous promoter regulatory elements. Mol Endocrinol. 1988 Apr;2(4):355–367. doi: 10.1210/mend-2-4-355. [DOI] [PubMed] [Google Scholar]
  368. Minvielle S., Cressent M., Lasmoles F., Jullienne A., Milhaud G., Moukhtar M. S. Isolation and partial characterization of the calcitonin gene in a lower vertebrate. Predicted structure of avian calcitonin gene-related peptide. FEBS Lett. 1986 Jul 14;203(1):7–10. doi: 10.1016/0014-5793(86)81425-9. [DOI] [PubMed] [Google Scholar]
  369. Mitchell P. J., Urlaub G., Chasin L. Spontaneous splicing mutations at the dihydrofolate reductase locus in Chinese hamster ovary cells. Mol Cell Biol. 1986 Jun;6(6):1926–1935. doi: 10.1128/mcb.6.6.1926. [DOI] [PMC free article] [PubMed] [Google Scholar]
  370. Miyatake S., Yokota T., Lee F., Arai K. Structure of the chromosomal gene for murine interleukin 3. Proc Natl Acad Sci U S A. 1985 Jan;82(2):316–320. doi: 10.1073/pnas.82.2.316. [DOI] [PMC free article] [PubMed] [Google Scholar]
  371. Miyatani S., Winkles J. A., Sargent T. D., Dawid I. B. Stage-specific keratins in Xenopus laevis embryos and tadpoles: the XK81 gene family. J Cell Biol. 1986 Nov;103(5):1957–1965. doi: 10.1083/jcb.103.5.1957. [DOI] [PMC free article] [PubMed] [Google Scholar]
  372. Miyazaki H., Fukamizu A., Hirose S., Hayashi T., Hori H., Ohkubo H., Nakanishi S., Murakami K. Structure of the human renin gene. Proc Natl Acad Sci U S A. 1984 Oct;81(19):5999–6003. doi: 10.1073/pnas.81.19.5999. [DOI] [PMC free article] [PubMed] [Google Scholar]
  373. Mizukami Y., Sogawa K., Suwa Y., Muramatsu M., Fujii-Kuriyama Y. Gene structure of a phenobarbital-inducible cytochrome P-450 in rat liver. Proc Natl Acad Sci U S A. 1983 Jul;80(13):3958–3962. doi: 10.1073/pnas.80.13.3958. [DOI] [PMC free article] [PubMed] [Google Scholar]
  374. Molloy P. L., Powell B. C., Gregg K., Barone E. D., Rogers G. E. Organisation of feather keratin genes in the chick genome. Nucleic Acids Res. 1982 Oct 11;10(19):6007–6021. doi: 10.1093/nar/10.19.6007. [DOI] [PMC free article] [PubMed] [Google Scholar]
  375. Monson J. M., Friedman J., McCarthy B. J. DNA sequence analysis of a mouse pro alpha 1 (I) procollagen gene: evidence for a mouse B1 element within the gene. Mol Cell Biol. 1982 Nov;2(11):1362–1371. doi: 10.1128/mcb.2.11.1362. [DOI] [PMC free article] [PubMed] [Google Scholar]
  376. Monson J. M., Natzle J., Friedman J., McCarthy B. J. Expression and novel structure of a collagen gene in Drosophila. Proc Natl Acad Sci U S A. 1982 Mar;79(6):1761–1765. doi: 10.1073/pnas.79.6.1761. [DOI] [PMC free article] [PubMed] [Google Scholar]
  377. Monteiro M. J., Cox R. A. Primary structure of an alpha-tubulin gene of Physarum polycephalum. J Mol Biol. 1987 Feb 5;193(3):427–438. doi: 10.1016/0022-2836(87)90257-9. [DOI] [PubMed] [Google Scholar]
  378. Montell C., Berk A. J. Elimination of mRNA splicing by a point mutation outside the conserved GU at 5' splice sites. Nucleic Acids Res. 1984 May 11;12(9):3821–3827. doi: 10.1093/nar/12.9.3821. [DOI] [PMC free article] [PubMed] [Google Scholar]
  379. Montminy M. R., Goodman R. H., Horovitch S. J., Habener J. F. Primary structure of the gene encoding rat preprosomatostatin. Proc Natl Acad Sci U S A. 1984 Jun;81(11):3337–3340. doi: 10.1073/pnas.81.11.3337. [DOI] [PMC free article] [PubMed] [Google Scholar]
  380. Morgan B. A., Johnson W. A., Hirsh J. Regulated splicing produces different forms of dopa decarboxylase in the central nervous system and hypoderm of Drosophila melanogaster. EMBO J. 1986 Dec 1;5(12):3335–3342. doi: 10.1002/j.1460-2075.1986.tb04648.x. [DOI] [PMC free article] [PubMed] [Google Scholar]
  381. Morgan J. G., Holbrook N. J., Crabtree G. R. Nucleotide sequence of the gamma chain gene of rat fibrinogen: conserved intronic sequences. Nucleic Acids Res. 1987 Mar 25;15(6):2774–2776. doi: 10.1093/nar/15.6.2774. [DOI] [PMC free article] [PubMed] [Google Scholar]
  382. Morgan W. R., Ward D. C. Three splicing patterns are used to excise the small intron common to all minute virus of mice RNAs. J Virol. 1986 Dec;60(3):1170–1174. doi: 10.1128/jvi.60.3.1170-1174.1986. [DOI] [PMC free article] [PubMed] [Google Scholar]
  383. Morishima N., Yoshioka H., Higashi Y., Sogawa K., Fujii-Kuriyama Y. Gene structure of cytochrome P-450(M-1) specifically expressed in male rat liver. Biochemistry. 1987 Dec 15;26(25):8279–8285. doi: 10.1021/bi00399a039. [DOI] [PubMed] [Google Scholar]
  384. Mount S. M. A catalogue of splice junction sequences. Nucleic Acids Res. 1982 Jan 22;10(2):459–472. doi: 10.1093/nar/10.2.459. [DOI] [PMC free article] [PubMed] [Google Scholar]
  385. Musti A. M., Avvedimento E. V., Polistina C., Ursini V. M., Obici S., Nitsch L., Cocozza S., Di Lauro R. The complete structure of the rat thyroglobulin gene. Proc Natl Acad Sci U S A. 1986 Jan;83(2):323–327. doi: 10.1073/pnas.83.2.323. [DOI] [PMC free article] [PubMed] [Google Scholar]
  386. Myerowitz R. Splice junction mutation in some Ashkenazi Jews with Tay-Sachs disease: evidence against a single defect within this ethnic group. Proc Natl Acad Sci U S A. 1988 Jun;85(11):3955–3959. doi: 10.1073/pnas.85.11.3955. [DOI] [PMC free article] [PubMed] [Google Scholar]
  387. Myslinski E., Branlant C., Wieben E. D., Pederson T. The small nuclear RNAs of Drosophila. J Mol Biol. 1984 Dec 25;180(4):927–945. doi: 10.1016/0022-2836(84)90264-x. [DOI] [PubMed] [Google Scholar]
  388. Müller R. M., Taguchi H., Shibahara S. Nucleotide sequence and organization of the rat heme oxygenase gene. J Biol Chem. 1987 May 15;262(14):6795–6802. [PubMed] [Google Scholar]
  389. Münger K., Germann U. A., Lerch K. Isolation and structural organization of the Neurospora crassa copper metallothionein gene. EMBO J. 1985 Oct;4(10):2665–2668. doi: 10.1002/j.1460-2075.1985.tb03985.x. [DOI] [PMC free article] [PubMed] [Google Scholar]
  390. N'Guyen C., Sodoyer R., Trucy J., Strachan T., Jordan B. R. The HLA-AW24 gene: sequence, surroundings and comparison with the HLA-A2 and HLA-A3 genes. Immunogenetics. 1985;21(5):479–489. doi: 10.1007/BF00430931. [DOI] [PubMed] [Google Scholar]
  391. Nabeshima Y., Fujii-Kuriyama Y., Muramatsu M., Ogata K. Alternative transcription and two modes of splicing results in two myosin light chains from one gene. Nature. 1984 Mar 22;308(5957):333–338. doi: 10.1038/308333a0. [DOI] [PubMed] [Google Scholar]
  392. Nagamine Y., Pearson D., Altus M. S., Reich E. cDNA and gene nucleotide sequence of porcine plasminogen activator. Nucleic Acids Res. 1984 Dec 21;12(24):9525–9541. doi: 10.1093/nar/12.24.9525. [DOI] [PMC free article] [PubMed] [Google Scholar]
  393. Nairn C. J., Winesett L., Ferl R. J. Nucleotide sequence of an actin gene from Arabidopsis thaliana. Gene. 1988 May 30;65(2):247–257. doi: 10.1016/0378-1119(88)90461-1. [DOI] [PubMed] [Google Scholar]
  394. Nakajima-Iijima S., Hamada H., Reddy P., Kakunaga T. Molecular structure of the human cytoplasmic beta-actin gene: interspecies homology of sequences in the introns. Proc Natl Acad Sci U S A. 1985 Sep;82(18):6133–6137. doi: 10.1073/pnas.82.18.6133. [DOI] [PMC free article] [PubMed] [Google Scholar]
  395. Nakanishi S., Teranishi Y., Noda M., Notake M., Watanabe Y., Kakidani H., Jingami H., Numa S. The protein-coding sequence of the bovine ACTH-beta-LPH precursor gene is split near the signal peptide region. Nature. 1980 Oct 23;287(5784):752–755. doi: 10.1038/287752a0. [DOI] [PubMed] [Google Scholar]
  396. Nakanishi T., Kohno K., Ishiura M., Ohashi H., Uchida T. Complete nucleotide sequence and characterization of the 5'-flanking region of mammalian elongation factor 2 gene. J Biol Chem. 1988 May 5;263(13):6384–6391. [PubMed] [Google Scholar]
  397. Nathans J., Hogness D. S. Isolation and nucleotide sequence of the gene encoding human rhodopsin. Proc Natl Acad Sci U S A. 1984 Aug;81(15):4851–4855. doi: 10.1073/pnas.81.15.4851. [DOI] [PMC free article] [PubMed] [Google Scholar]
  398. Nathans J., Hogness D. S. Isolation, sequence analysis, and intron-exon arrangement of the gene encoding bovine rhodopsin. Cell. 1983 Oct;34(3):807–814. doi: 10.1016/0092-8674(83)90537-8. [DOI] [PubMed] [Google Scholar]
  399. Nave K. A., Lai C., Bloom F. E., Milner R. J. Splice site selection in the proteolipid protein (PLP) gene transcript and primary structure of the DM-20 protein of central nervous system myelin. Proc Natl Acad Sci U S A. 1987 Aug;84(16):5665–5669. doi: 10.1073/pnas.84.16.5665. [DOI] [PMC free article] [PubMed] [Google Scholar]
  400. Nawa H., Kotani H., Nakanishi S. Tissue-specific generation of two preprotachykinin mRNAs from one gene by alternative RNA splicing. Nature. 1984 Dec 20;312(5996):729–734. doi: 10.1038/312729a0. [DOI] [PubMed] [Google Scholar]
  401. Nef P., Mauron A., Stalder R., Alliod C., Ballivet M. Structure linkage, and sequence of the two genes encoding the delta and gamma subunits of the nicotinic acetylcholine receptor. Proc Natl Acad Sci U S A. 1984 Dec;81(24):7975–7979. doi: 10.1073/pnas.81.24.7975. [DOI] [PMC free article] [PubMed] [Google Scholar]
  402. Nef P., Oneyser C., Alliod C., Couturier S., Ballivet M. Genes expressed in the brain define three distinct neuronal nicotinic acetylcholine receptors. EMBO J. 1988 Mar;7(3):595–601. doi: 10.1002/j.1460-2075.1988.tb02852.x. [DOI] [PMC free article] [PubMed] [Google Scholar]
  403. Negrini M., Silini E., Kozak C., Tsujimoto Y., Croce C. M. Molecular analysis of mbcl-2: structure and expression of the murine gene homologous to the human gene involved in follicular lymphoma. Cell. 1987 May 22;49(4):455–463. doi: 10.1016/0092-8674(87)90448-x. [DOI] [PubMed] [Google Scholar]
  404. Nellen W., Donath C., Moos M., Gallwitz D. The nucleotide sequences of the actin genes from Saccharomyces carlsbergensis and Saccharomyces cerevisiae are identical except for their introns. J Mol Appl Genet. 1981;1(3):239–244. [PubMed] [Google Scholar]
  405. Nellen W., Gallwitz D. Actin genes and actin messenger RNA in Acanthamoeba castellanii. Nucleotide sequence of the split actin gene I. J Mol Biol. 1982 Jul 25;159(1):1–18. doi: 10.1016/0022-2836(82)90028-6. [DOI] [PubMed] [Google Scholar]
  406. Nemer M., Chamberland M., Sirois D., Argentin S., Drouin J., Dixon R. A., Zivin R. A., Condra J. H. Gene structure of human cardiac hormone precursor, pronatriodilatin. Nature. 1984 Dec 13;312(5995):654–656. doi: 10.1038/312654a0. [DOI] [PubMed] [Google Scholar]
  407. Ng R., Abelson J. Isolation and sequence of the gene for actin in Saccharomyces cerevisiae. Proc Natl Acad Sci U S A. 1980 Jul;77(7):3912–3916. doi: 10.1073/pnas.77.7.3912. [DOI] [PMC free article] [PubMed] [Google Scholar]
  408. Nickerson J. M., Wawrousek E. F., Borras T., Hawkins J. W., Norman B. L., Filpula D. R., Nagle J. W., Ally A. H., Piatigorsky J. Sequence of the chicken delta 2 crystallin gene and its intergenic spacer. Extreme homology with the delta 1 crystallin gene. J Biol Chem. 1986 Jan 15;261(2):552–557. [PubMed] [Google Scholar]
  409. Nielsen H., Andreasen P. H., Dreisig H., Kristiansen K., Engberg J. An intron in a ribosomal protein gene from Tetrahymena. EMBO J. 1986 Oct;5(10):2711–2717. doi: 10.1002/j.1460-2075.1986.tb04555.x. [DOI] [PMC free article] [PubMed] [Google Scholar]
  410. Nishide T., Nakamura Y., Emi M., Yamamoto T., Ogawa M., Mori T., Matsubara K. Primary structure of human salivary alpha-amylase gene. Gene. 1986;41(2-3):299–304. doi: 10.1016/0378-1119(86)90110-1. [DOI] [PubMed] [Google Scholar]
  411. Nishioka Y., Leder P. Organization and complete sequence of identical embryonic and plasmacytoma kappa V-region genes. J Biol Chem. 1980 Apr 25;255(8):3691–3694. [PubMed] [Google Scholar]
  412. Nishizawa M., Semba K., Yoshida M. C., Yamamoto T., Sasaki M., Toyoshima K. Structure, expression, and chromosomal location of the human c-fgr gene. Mol Cell Biol. 1986 Feb;6(2):511–517. doi: 10.1128/mcb.6.2.511. [DOI] [PMC free article] [PubMed] [Google Scholar]
  413. Nudel U., Calvo J. M., Shani M., Levy Z. The nucleotide sequence of a rat myosin light chain 2 gene. Nucleic Acids Res. 1984 Sep 25;12(18):7175–7186. doi: 10.1093/nar/12.18.7175. [DOI] [PMC free article] [PubMed] [Google Scholar]
  414. Nudel U., Zakut R., Shani M., Neuman S., Levy Z., Yaffe D. The nucleotide sequence of the rat cytoplasmic beta-actin gene. Nucleic Acids Res. 1983 Mar 25;11(6):1759–1771. doi: 10.1093/nar/11.6.1759. [DOI] [PMC free article] [PubMed] [Google Scholar]
  415. Ny T., Elgh F., Lund B. The structure of the human tissue-type plasminogen activator gene: correlation of intron and exon structures to functional and structural domains. Proc Natl Acad Sci U S A. 1984 Sep;81(17):5355–5359. doi: 10.1073/pnas.81.17.5355. [DOI] [PMC free article] [PubMed] [Google Scholar]
  416. O'Malley K. L., Anhalt M. J., Martin B. M., Kelsoe J. R., Winfield S. L., Ginns E. I. Isolation and characterization of the human tyrosine hydroxylase gene: identification of 5' alternative splice sites responsible for multiple mRNAs. Biochemistry. 1987 Nov 3;26(22):6910–6914. doi: 10.1021/bi00396a007. [DOI] [PubMed] [Google Scholar]
  417. Oakley B. R., Rinehart J. E., Mitchell B. L., Oakley C. E., Carmona C., Gray G. L., May G. S. Cloning, mapping and molecular analysis of the pyrG (orotidine-5'-phosphate decarboxylase) gene of Aspergillus nidulans. Gene. 1987;61(3):385–399. doi: 10.1016/0378-1119(87)90201-0. [DOI] [PubMed] [Google Scholar]
  418. Obaru K., Tsuzuki T., Setoyama C., Shimada K. Structural organization of the mouse aspartate aminotransferase isoenzyme genes. Introns antedate the divergence of cytosolic and mitochondrial isoenzyme genes. J Mol Biol. 1988 Mar 5;200(1):13–22. doi: 10.1016/0022-2836(88)90329-4. [DOI] [PubMed] [Google Scholar]
  419. Ohno K., Suzuki K. A splicing defect due to an exon-intron junctional mutation results in abnormal beta-hexosaminidase alpha chain mRNAs in Ashkenazi Jewish patients with Tay-Sachs disease. Biochem Biophys Res Commun. 1988 May 31;153(1):463–469. doi: 10.1016/s0006-291x(88)81247-6. [DOI] [PubMed] [Google Scholar]
  420. Ohshima Y., Gotoh Y. Signals for the selection of a splice site in pre-mRNA. Computer analysis of splice junction sequences and like sequences. J Mol Biol. 1987 May 20;195(2):247–259. doi: 10.1016/0022-2836(87)90647-4. [DOI] [PubMed] [Google Scholar]
  421. Ohtake A., Takiguchi M., Shigeto Y., Amaya Y., Kawamoto S., Mori M. Structural organization of the gene for rat liver-type arginase. J Biol Chem. 1988 Feb 15;263(5):2245–2249. [PubMed] [Google Scholar]
  422. Okamoto H., Ishikawa E., Suzuki Y. Structural analysis of sericin genes. Homologies with fibroin gene in the 5' flanking nucleotide sequences. J Biol Chem. 1982 Dec 25;257(24):15192–15199. [PubMed] [Google Scholar]
  423. Okuda A., Sakai M., Muramatsu M. The structure of the rat glutathione S-transferase P gene and related pseudogenes. J Biol Chem. 1987 Mar 15;262(8):3858–3863. [PubMed] [Google Scholar]
  424. Ollo R., Auffray C., Morchamps C., Rougeon F. Comparison of mouse immunoglobulin gamma 2a and gamma 2b chain genes suggests that exons can be exchanged between genes in a multigenic family. Proc Natl Acad Sci U S A. 1981 Apr;78(4):2442–2446. doi: 10.1073/pnas.78.4.2442. [DOI] [PMC free article] [PubMed] [Google Scholar]
  425. Ollo R., Auffray C., Sikorav J. L., Rougeon F. Mouse heavy chain variable regions: nucleotide sequence of a germ-line VH gene segment. Nucleic Acids Res. 1981 Aug 25;9(16):4099–4109. doi: 10.1093/nar/9.16.4099. [DOI] [PMC free article] [PubMed] [Google Scholar]
  426. Ollo R., Rougeon F. Gene conversion and polymorphism: generation of mouse immunoglobulin gamma 2a chain alleles by differential gene conversion by gamma 2b chain gene. Cell. 1983 Feb;32(2):515–523. doi: 10.1016/0092-8674(83)90471-3. [DOI] [PubMed] [Google Scholar]
  427. Ollo R., Rougeon F. Mouse immunoglobulin allotypes: post-duplication divergence of gamma 2a and gamma 2b chain genes. Nature. 1982 Apr 22;296(5859):761–763. doi: 10.1038/296761a0. [DOI] [PubMed] [Google Scholar]
  428. Oppenheimer D. G., Haas N., Silflow C. D., Snustad D. P. The beta-tubulin gene family of Arabidopsis thaliana: preferential accumulation of the beta 1 transcript in roots. Gene. 1988;63(1):87–102. doi: 10.1016/0378-1119(88)90548-3. [DOI] [PubMed] [Google Scholar]
  429. Osumi T., Ishii N., Miyazawa S., Hashimoto T. Isolation and structural characterization of the rat acyl-CoA oxidase gene. J Biol Chem. 1987 Jun 15;262(17):8138–8143. [PubMed] [Google Scholar]
  430. Ovchinnikov YuA, Monastyrskaya G. S., Broude N. E., Ushkaryov YuA, Melkov A. M., Smirnov YuV, Malyshev I. V., Allikmets R. L., Kostina M. B., Dulubova I. E. Family of human Na+, K+-ATPase genes. Structure of the gene for the catalytic subunit (alpha III-form) and its relationship with structural features of the protein. FEBS Lett. 1988 Jun 6;233(1):87–94. doi: 10.1016/0014-5793(88)81361-9. [DOI] [PubMed] [Google Scholar]
  431. Padgett R. A., Grabowski P. J., Konarska M. M., Seiler S., Sharp P. A. Splicing of messenger RNA precursors. Annu Rev Biochem. 1986;55:1119–1150. doi: 10.1146/annurev.bi.55.070186.005351. [DOI] [PubMed] [Google Scholar]
  432. Page G. S., Smith S., Goodman H. M. DNA sequence of the rat growth hormone gene: location of the 5' terminus of the growth hormone mRNA and identification of an internal transposon-like element. Nucleic Acids Res. 1981 May 11;9(9):2087–2104. doi: 10.1093/nar/9.9.2087. [DOI] [PMC free article] [PubMed] [Google Scholar]
  433. Paik Y. K., Chang D. J., Reardon C. A., Davies G. E., Mahley R. W., Taylor J. M. Nucleotide sequence and structure of the human apolipoprotein E gene. Proc Natl Acad Sci U S A. 1985 May;82(10):3445–3449. doi: 10.1073/pnas.82.10.3445. [DOI] [PMC free article] [PubMed] [Google Scholar]
  434. Pan T. C., Hao Q. L., Yamin T. T., Dai P. H., Chen B. S., Chen S. L., Kroon P. A., Chao Y. S. Rabbit apolipoprotein A-I mRNA and gene. Evidence that rabbit apolipoprotein A-I is synthesized in the intestine but not in the liver. Eur J Biochem. 1987 Dec 30;170(1-2):99–104. doi: 10.1111/j.1432-1033.1987.tb13672.x. [DOI] [PubMed] [Google Scholar]
  435. Paolella G., Henchcliffe C., Sebastio G., Baralle F. E. Sequence analysis and in vivo expression show that alternative splicing of ED-B and ED-A regions of the human fibronectin gene are independent events. Nucleic Acids Res. 1988 Apr 25;16(8):3545–3557. doi: 10.1093/nar/16.8.3545. [DOI] [PMC free article] [PubMed] [Google Scholar]
  436. Parma J., Christophe D., Pohl V., Vassart G. Structural organization of the 5' region of the thyroglobulin gene. Evidence for intron loss and "exonization" during evolution. J Mol Biol. 1987 Aug 20;196(4):769–779. doi: 10.1016/0022-2836(87)90403-7. [DOI] [PubMed] [Google Scholar]
  437. Parslow T. G., Blair D. L., Murphy W. J., Granner D. K. Structure of the 5' ends of immunoglobulin genes: a novel conserved sequence. Proc Natl Acad Sci U S A. 1984 May;81(9):2650–2654. doi: 10.1073/pnas.81.9.2650. [DOI] [PMC free article] [PubMed] [Google Scholar]
  438. Patient R. K., Harris R., Walmsley M. E., Williams J. G. The complete nucleotide sequence of the major adult beta globin gene of Xenopus laevis. J Biol Chem. 1983 Jul 25;258(14):8521–8523. [PubMed] [Google Scholar]
  439. Pauli D., Tonka C. H., Ayme-Southgate A. An unusual split Drosophila heat shock gene expressed during embryogenesis, pupation and in testis. J Mol Biol. 1988 Mar 5;200(1):47–53. doi: 10.1016/0022-2836(88)90332-4. [DOI] [PubMed] [Google Scholar]
  440. Pech M., Zachau H. G. Immunoglobulin genes of different subgroups are interdigitated within the VK locus. Nucleic Acids Res. 1984 Dec 21;12(24):9229–9236. doi: 10.1093/nar/12.24.9229. [DOI] [PMC free article] [PubMed] [Google Scholar]
  441. Perler F., Efstratiadis A., Lomedico P., Gilbert W., Kolodner R., Dodgson J. The evolution of genes: the chicken preproinsulin gene. Cell. 1980 Jun;20(2):555–566. doi: 10.1016/0092-8674(80)90641-8. [DOI] [PubMed] [Google Scholar]
  442. Perret C., Lomri N., Gouhier N., Auffray C., Thomasset M. The rat vitamin-D-dependent calcium-binding protein (9-kDa CaBP) gene. Complete nucleotide sequence and structural organization. Eur J Biochem. 1988 Feb 15;172(1):43–51. doi: 10.1111/j.1432-1033.1988.tb13853.x. [DOI] [PubMed] [Google Scholar]
  443. Peterson M. G., Hannan F., Mercer J. F. The sheep metallothionein gene family. Structure, sequence and evolutionary relationship of five linked genes. Eur J Biochem. 1988 Jun 1;174(2):417–424. doi: 10.1111/j.1432-1033.1988.tb14114.x. [DOI] [PubMed] [Google Scholar]
  444. Phillips M., Djian P., Green H. The nucleotide sequence of three genes participating in the adipose differentiation of 3T3 cells. J Biol Chem. 1986 Aug 15;261(23):10821–10827. [PubMed] [Google Scholar]
  445. Picado-Leonard J., Miller W. L. Cloning and sequence of the human gene for P450c17 (steroid 17 alpha-hydroxylase/17,20 lyase): similarity with the gene for P450c21. DNA. 1987 Oct;6(5):439–448. doi: 10.1089/dna.1987.6.439. [DOI] [PubMed] [Google Scholar]
  446. Pikaard C. S., Mignery G. A., Ma D. P., Stark V. J., Park W. D. Sequence of two apparent pseudogenes of the major potato tuber protein, patatin. Nucleic Acids Res. 1986 Jul 11;14(13):5564–5566. doi: 10.1093/nar/14.13.5564. [DOI] [PMC free article] [PubMed] [Google Scholar]
  447. Policastro P., Ovitt C. E., Hoshina M., Fukuoka H., Boothby M. R., Boime I. The beta subunit of human chorionic gonadotropin is encoded by multiple genes. J Biol Chem. 1983 Oct 10;258(19):11492–11499. [PubMed] [Google Scholar]
  448. Poncz M., Schwartz E., Ballantine M., Surrey S. Nucleotide sequence analysis of the delta beta-globin gene region in humans. J Biol Chem. 1983 Oct 10;258(19):11599–11609. [PubMed] [Google Scholar]
  449. Pontarotti P. A., Mashimo H., Zeff R. A., Fisher D. A., Hood L., Mellor A., Flavell R. A., Nathenson S. G. Conservation and diversity in the class I genes of the major histocompatibility complex: sequence analysis of a Tlab gene and comparison with a Tlac gene. Proc Natl Acad Sci U S A. 1986 Mar;83(6):1782–1786. doi: 10.1073/pnas.83.6.1782. [DOI] [PMC free article] [PubMed] [Google Scholar]
  450. Pratt L. F., Cleveland D. W. A survey of the alpha-tubulin gene family in chicken: unexpected sequence heterogeneity in the polypeptides encoded by five expressed genes. EMBO J. 1988 Apr;7(4):931–940. doi: 10.1002/j.1460-2075.1988.tb02898.x. [DOI] [PMC free article] [PubMed] [Google Scholar]
  451. Proia R. L. Gene encoding the human beta-hexosaminidase beta chain: extensive homology of intron placement in the alpha- and beta-chain genes. Proc Natl Acad Sci U S A. 1988 Mar;85(6):1883–1887. doi: 10.1073/pnas.85.6.1883. [DOI] [PMC free article] [PubMed] [Google Scholar]
  452. Proia R. L., Soravia E. Organization of the gene encoding the human beta-hexosaminidase alpha-chain. J Biol Chem. 1987 Apr 25;262(12):5677–5681. [PubMed] [Google Scholar]
  453. Punt P. J., Dingemanse M. A., Jacobs-Meijsing B. J., Pouwels P. H., van den Hondel C. A. Isolation and characterization of the glyceraldehyde-3-phosphate dehydrogenase gene of Aspergillus nidulans. Gene. 1988 Sep 15;69(1):49–57. doi: 10.1016/0378-1119(88)90377-0. [DOI] [PubMed] [Google Scholar]
  454. Qasba P. K., Safaya S. K. Similarity of the nucleotide sequences of rat alpha-lactalbumin and chicken lysozyme genes. Nature. 1984 Mar 22;308(5957):377–380. doi: 10.1038/308377a0. [DOI] [PubMed] [Google Scholar]
  455. Quax-Jeuken Y., Quax W., van Rens G., Khan P. M., Bloemendal H. Complete structure of the alpha B-crystallin gene: conservation of the exon-intron distribution in the two nonlinked alpha-crystallin genes. Proc Natl Acad Sci U S A. 1985 Sep;82(17):5819–5823. doi: 10.1073/pnas.82.17.5819. [DOI] [PMC free article] [PubMed] [Google Scholar]
  456. Quax W., Egberts W. V., Hendriks W., Quax-Jeuken Y., Bloemendal H. The structure of the vimentin gene. Cell. 1983 Nov;35(1):215–223. doi: 10.1016/0092-8674(83)90224-6. [DOI] [PubMed] [Google Scholar]
  457. Quax W., van den Broek L., Egberts W. V., Ramaekers F., Bloemendal H. Characterization of the hamster desmin gene: expression and formation of desmin filaments in nonmuscle cells after gene transfer. Cell. 1985 Nov;43(1):327–338. doi: 10.1016/0092-8674(85)90038-8. [DOI] [PubMed] [Google Scholar]
  458. Rabbitts T. H., Forster A., Milstein C. P. Human immunoglobulin heavy chain genes: evolutionary comparisons of C mu, C delta and C gamma genes and associated switch sequences. Nucleic Acids Res. 1981 Sep 25;9(18):4509–4524. doi: 10.1093/nar/9.18.4509. [DOI] [PMC free article] [PubMed] [Google Scholar]
  459. Rabbitts T. H., Hamlyn P. H., Baer R. Altered nucleotide sequences of a translocated c-myc gene in Burkitt lymphoma. Nature. 1983 Dec 22;306(5945):760–765. doi: 10.1038/306760a0. [DOI] [PubMed] [Google Scholar]
  460. Rafti F., Gargiulo G., Manzi A., Malva C., Grossi G., Andone S., Graziani F. Isolation and structural analysis of a ribosomal protein gene in D.melanogaster. Nucleic Acids Res. 1988 Jun 10;16(11):4915–4926. doi: 10.1093/nar/16.11.4915. [DOI] [PMC free article] [PubMed] [Google Scholar]
  461. Ragg H., Preibisch G. Structure and expression of the gene coding for the human serpin hLS2. J Biol Chem. 1988 Aug 25;263(24):12129–12134. [PubMed] [Google Scholar]
  462. Ravetch J. V., Siebenlist U., Korsmeyer S., Waldmann T., Leder P. Structure of the human immunoglobulin mu locus: characterization of embryonic and rearranged J and D genes. Cell. 1981 Dec;27(3 Pt 2):583–591. doi: 10.1016/0092-8674(81)90400-1. [DOI] [PubMed] [Google Scholar]
  463. Rechavi G., Ram D., Glazer L., Zakut R., Givol D. Evolutionary aspects of immunoglobulin heavy chain variable region (VH) gene subgroups. Proc Natl Acad Sci U S A. 1983 Feb;80(3):855–859. doi: 10.1073/pnas.80.3.855. [DOI] [PMC free article] [PubMed] [Google Scholar]
  464. Reddy R., Ro-Choi T. S., Henning D., Busch H. Primary sequence of U-1 nuclear ribonucleic acid of Novikoff hepatoma ascites cells. J Biol Chem. 1974 Oct 25;249(20):6486–6494. [PubMed] [Google Scholar]
  465. Rees D. J., Rizza C. R., Brownlee G. G. Haemophilia B caused by a point mutation in a donor splice junction of the human factor IX gene. Nature. 1985 Aug 15;316(6029):643–645. doi: 10.1038/316643a0. [DOI] [PubMed] [Google Scholar]
  466. Reich N., Evans B., Levy D., Fahey D., Knight E., Jr, Darnell J. E., Jr Interferon-induced transcription of a gene encoding a 15-kDa protein depends on an upstream enhancer element. Proc Natl Acad Sci U S A. 1987 Sep;84(18):6394–6398. doi: 10.1073/pnas.84.18.6394. [DOI] [PMC free article] [PubMed] [Google Scholar]
  467. Repaske R., Steele P. E., O'Neill R. R., Rabson A. B., Martin M. A. Nucleotide sequence of a full-length human endogenous retroviral segment. J Virol. 1985 Jun;54(3):764–772. doi: 10.1128/jvi.54.3.764-772.1985. [DOI] [PMC free article] [PubMed] [Google Scholar]
  468. Rhodes C., Doege K., Sasaki M., Yamada Y. Alternative splicing generates two different mRNA species for rat link protein. J Biol Chem. 1988 May 5;263(13):6063–6067. [PubMed] [Google Scholar]
  469. Riccio A., Grimaldi G., Verde P., Sebastio G., Boast S., Blasi F. The human urokinase-plasminogen activator gene and its promoter. Nucleic Acids Res. 1985 Apr 25;13(8):2759–2771. doi: 10.1093/nar/13.8.2759. [DOI] [PMC free article] [PubMed] [Google Scholar]
  470. Richards J. E., Gilliam A. C., Shen A., Tucker P. W., Blattner F. R. Unusual sequences in the murine immunoglobulin mu-delta heavy-chain region. Nature. 1983 Dec 1;306(5942):483–487. doi: 10.1038/306483a0. [DOI] [PubMed] [Google Scholar]
  471. Rieger M., Jorcano J. L., Franke W. W. Complete sequence of a bovine type I cytokeratin gene: conserved and variable intron positions in genes of polypeptides of the same cytokeratin subfamily. EMBO J. 1985 Sep;4(9):2261–2267. doi: 10.1002/j.1460-2075.1985.tb03924.x. [DOI] [PMC free article] [PubMed] [Google Scholar]
  472. Riley L. K., Morrow J. K., Danton M. J., Coleman M. S. Human terminal deoxyribonucleotidyltransferase: molecular cloning and structural analysis of the gene and 5' flanking region. Proc Natl Acad Sci U S A. 1988 Apr;85(8):2489–2493. doi: 10.1073/pnas.85.8.2489. [DOI] [PMC free article] [PubMed] [Google Scholar]
  473. Rinke J., Appel B., Blöcker H., Frank R., Lührmann R. The 5'-terminal sequence of U1 RNA complementary to the consensus 5' splice site of hnRNA is single-stranded in intact U1 snRNP particles. Nucleic Acids Res. 1984 May 25;12(10):4111–4126. doi: 10.1093/nar/12.10.4111. [DOI] [PMC free article] [PubMed] [Google Scholar]
  474. Rixon M. W., Chung D. W., Davie E. W. Nucleotide sequence of the gene for the gamma chain of human fibrinogen. Biochemistry. 1985 Apr 9;24(8):2077–2086. doi: 10.1021/bi00329a041. [DOI] [PubMed] [Google Scholar]
  475. Rochester D. E., Winer J. A., Shah D. M. The structure and expression of maize genes encoding the major heat shock protein, hsp70. EMBO J. 1986 Mar;5(3):451–458. doi: 10.1002/j.1460-2075.1986.tb04233.x. [DOI] [PMC free article] [PubMed] [Google Scholar]
  476. Roebroek A. J., Schalken J. A., Verbeek J. S., Van den Ouweland A. M., Onnekink C., Bloemers H. P., Van de Ven W. J. The structure of the human c-fes/fps proto-oncogene. EMBO J. 1985 Nov;4(11):2897–2903. doi: 10.1002/j.1460-2075.1985.tb04020.x. [DOI] [PMC free article] [PubMed] [Google Scholar]
  477. Rogers J., Wall R. A mechanism for RNA splicing. Proc Natl Acad Sci U S A. 1980 Apr;77(4):1877–1879. doi: 10.1073/pnas.77.4.1877. [DOI] [PMC free article] [PubMed] [Google Scholar]
  478. Rohde W., Becker D., Salamini F. Structural analysis of the waxy locus from Hordeum vulgare. Nucleic Acids Res. 1988 Jul 25;16(14B):7185–7186. doi: 10.1093/nar/16.14.7185. [DOI] [PMC free article] [PubMed] [Google Scholar]
  479. Rohrbaugh M. L., Johnson J. E., 3rd, James M. D., Hardison R. C. Transcription unit of the rabbit beta 1 globin gene. Mol Cell Biol. 1985 Jan;5(1):147–160. doi: 10.1128/mcb.5.1.147. [DOI] [PMC free article] [PubMed] [Google Scholar]
  480. Romana M., Dubart A., Beaupain D., Chabret C., Goossens M., Romeo P. H. Structure of the gene for human uroporphyrinogen decarboxylase. Nucleic Acids Res. 1987 Sep 25;15(18):7343–7356. doi: 10.1093/nar/15.18.7343. [DOI] [PMC free article] [PubMed] [Google Scholar]
  481. Rorsman F., Bywater M., Knott T. J., Scott J., Betsholtz C. Structural characterization of the human platelet-derived growth factor A-chain cDNA and gene: alternative exon usage predicts two different precursor proteins. Mol Cell Biol. 1988 Feb;8(2):571–577. doi: 10.1128/mcb.8.2.571. [DOI] [PMC free article] [PubMed] [Google Scholar]
  482. Rosenthal A., Rhee L., Yadegari R., Paro R., Ullrich A., Goeddel D. V. Structure and nucleotide sequence of a Drosophila melanogaster protein kinase C gene. EMBO J. 1987 Feb;6(2):433–441. doi: 10.1002/j.1460-2075.1987.tb04773.x. [DOI] [PMC free article] [PubMed] [Google Scholar]
  483. Rossi P., de Crombrugghe B. Identification of a cell-specific transcriptional enhancer in the first intron of the mouse alpha 2 (type I) collagen gene. Proc Natl Acad Sci U S A. 1987 Aug;84(16):5590–5594. doi: 10.1073/pnas.84.16.5590. [DOI] [PMC free article] [PubMed] [Google Scholar]
  484. Rotwein P., Pollock K. M., Didier D. K., Krivi G. G. Organization and sequence of the human insulin-like growth factor I gene. Alternative RNA processing produces two insulin-like growth factor I precursor peptides. J Biol Chem. 1986 Apr 15;261(11):4828–4832. [PubMed] [Google Scholar]
  485. Ruppert J. M., Kinzler K. W., Wong A. J., Bigner S. H., Kao F. T., Law M. L., Seuanez H. N., O'Brien S. J., Vogelstein B. The GLI-Kruppel family of human genes. Mol Cell Biol. 1988 Aug;8(8):3104–3113. doi: 10.1128/mcb.8.8.3104. [DOI] [PMC free article] [PubMed] [Google Scholar]
  486. Ruskin B., Pikielny C. W., Rosbash M., Green M. R. Alternative branch points are selected during splicing of a yeast pre-mRNA in mammalian and yeast extracts. Proc Natl Acad Sci U S A. 1986 Apr;83(7):2022–2026. doi: 10.1073/pnas.83.7.2022. [DOI] [PMC free article] [PubMed] [Google Scholar]
  487. Ruta M., Wolford R., Dhar R., Defeo-Jones D., Ellis R. W., Scolnick E. M. Nucleotide sequence of the two rat cellular rasH genes. Mol Cell Biol. 1986 May;6(5):1706–1710. doi: 10.1128/mcb.6.5.1706. [DOI] [PMC free article] [PubMed] [Google Scholar]
  488. Saga Y., Tung J. S., Shen F. W., Boyse E. A. Alternative use of 5' exons in the specification of Ly-5 isoforms distinguishing hematopoietic cell lineages. Proc Natl Acad Sci U S A. 1987 Aug;84(15):5364–5368. doi: 10.1073/pnas.84.15.5364. [DOI] [PMC free article] [PubMed] [Google Scholar]
  489. Saito H., Maki R. A., Clayton L. K., Tonegawa S. Complete primary structures of the E beta chain and gene of the mouse major histocompatibility complex. Proc Natl Acad Sci U S A. 1983 Sep;80(18):5520–5524. doi: 10.1073/pnas.80.18.5520. [DOI] [PMC free article] [PubMed] [Google Scholar]
  490. Sakano H., Hüppi K., Heinrich G., Tonegawa S. Sequences at the somatic recombination sites of immunoglobulin light-chain genes. Nature. 1979 Jul 26;280(5720):288–294. doi: 10.1038/280288a0. [DOI] [PubMed] [Google Scholar]
  491. Sakano H., Maki R., Kurosawa Y., Roeder W., Tonegawa S. Two types of somatic recombination are necessary for the generation of complete immunoglobulin heavy-chain genes. Nature. 1980 Aug 14;286(5774):676–683. doi: 10.1038/286676a0. [DOI] [PubMed] [Google Scholar]
  492. Sakurai H., Fujii T., Izumi S., Tomino S. Structure and expression of gene coding for sex-specific storage protein of Bombyx mori. J Biol Chem. 1988 Jun 5;263(16):7876–7880. [PubMed] [Google Scholar]
  493. Sangiorgi F. O., Benson-Chanda V., de Wet W. J., Sobel M. E., Tsipouras P., Ramirez F. Isolation and partial characterization of the entire human pro alpha 1(II) collagen gene. Nucleic Acids Res. 1985 Apr 11;13(7):2207–2225. doi: 10.1093/nar/13.7.2207. [DOI] [PMC free article] [PubMed] [Google Scholar]
  494. Sargent T. D., Jagodzinski L. L., Yang M., Bonner J. Fine structure and evolution of the rat serum albumin gene. Mol Cell Biol. 1981 Oct;1(10):871–883. doi: 10.1128/mcb.1.10.871. [DOI] [PMC free article] [PubMed] [Google Scholar]
  495. Savatier P., Trabuchet G., Faure C., Chebloune Y., Gouy M., Verdier G., Nigon V. M. Evolution of the primate beta-globin gene region. High rate of variation in CpG dinucleotides and in short repeated sequences between man and chimpanzee. J Mol Biol. 1985 Mar 5;182(1):21–29. doi: 10.1016/0022-2836(85)90024-5. [DOI] [PubMed] [Google Scholar]
  496. Schedlich L. J., Bennetts B. H., Morris B. J. Primary structure of a human glandular kallikrein gene. DNA. 1987 Oct;6(5):429–437. doi: 10.1089/dna.1987.6.429. [DOI] [PubMed] [Google Scholar]
  497. Schepart B. S., Takahashi H., Cozad K. M., Murray R., Ozato K., Appella E., Frelinger J. A. The nucleotide sequence and comparative analysis of the H-2Dp class I H-2 gene. J Immunol. 1986 May 1;136(9):3489–3495. [PubMed] [Google Scholar]
  498. Scherf A., Hilbich C., Sieg K., Mattei D., Mercereau-Puijalon O., Müller-Hill B. The 11-1 gene of Plasmodium falciparum codes for distinct fast evolving repeats. EMBO J. 1988 Apr;7(4):1129–1137. doi: 10.1002/j.1460-2075.1988.tb02922.x. [DOI] [PMC free article] [PubMed] [Google Scholar]
  499. Schmale H., Ivell R., Breindl M., Darmer D., Richter D. The mutant vasopressin gene from diabetes insipidus (Brattleboro) rats is transcribed but the message is not efficiently translated. EMBO J. 1984 Dec 20;3(13):3289–3293. doi: 10.1002/j.1460-2075.1984.tb02291.x. [DOI] [PMC free article] [PubMed] [Google Scholar]
  500. Schmidt C. J., Jubier M. F., Hamer D. H. Structure and expression of two human metallothionein-I isoform genes and a related pseudogene. J Biol Chem. 1985 Jun 25;260(12):7731–7737. [PubMed] [Google Scholar]
  501. Schon E. A., Cleary M. L., Haynes J. R., Lingrel J. B. Structure and evolution of goat gamma-, beta C- and beta A-globin genes: three developmentally regulated genes contain inserted elements. Cell. 1981 Dec;27(2 Pt 1):359–369. doi: 10.1016/0092-8674(81)90419-0. [DOI] [PubMed] [Google Scholar]
  502. Schon E. A., Wernke S. M., Lingrel J. B. Gene conversion of two functional goat alpha-globin genes preserves only minimal flanking sequences. J Biol Chem. 1982 Jun 25;257(12):6825–6835. [PubMed] [Google Scholar]
  503. Schuler M. A., McOsker P., Keller E. B. DNA sequence of two linked actin genes of sea urchin. Mol Cell Biol. 1983 Mar;3(3):448–456. doi: 10.1128/mcb.3.3.448. [DOI] [PMC free article] [PubMed] [Google Scholar]
  504. Schuler M. A., Schmitt E. S., Beachy R. N. Closely related families of genes code for the alpha and alpha' subunits of the soybean 7S storage protein complex. Nucleic Acids Res. 1982 Dec 20;10(24):8225–8244. doi: 10.1093/nar/10.24.8225. [DOI] [PMC free article] [PubMed] [Google Scholar]
  505. Schwarzbauer J. E., Patel R. S., Fonda D., Hynes R. O. Multiple sites of alternative splicing of the rat fibronectin gene transcript. EMBO J. 1987 Sep;6(9):2573–2580. doi: 10.1002/j.1460-2075.1987.tb02547.x. [DOI] [PMC free article] [PubMed] [Google Scholar]
  506. Scott A. F., Heath P., Trusko S., Boyer S. H., Prass W., Goodman M., Czelusniak J., Chang L. Y., Slightom J. L. The sequence of the gorilla fetal globin genes: evidence for multiple gene conversions in human evolution. Mol Biol Evol. 1984 Sep;1(5):371–389. doi: 10.1093/oxfordjournals.molbev.a040325. [DOI] [PubMed] [Google Scholar]
  507. Seidman C. E., Bloch K. D., Klein K. A., Smith J. A., Seidman J. G. Nucleotide sequences of the human and mouse atrial natriuretic factor genes. Science. 1984 Dec 7;226(4679):1206–1209. doi: 10.1126/science.6542248. [DOI] [PubMed] [Google Scholar]
  508. Seidman J. G., Max E. E., Leder P. A kappa-immunoglobulin gene is formed by site-specific recombination without further somatic mutation. Nature. 1979 Aug 2;280(5721):370–375. doi: 10.1038/280370a0. [DOI] [PubMed] [Google Scholar]
  509. Seki T., Spurr N., Obata F., Goyert S., Goodfellow P., Silver J. The human Thy-1 gene: structure and chromosomal location. Proc Natl Acad Sci U S A. 1985 Oct;82(19):6657–6661. doi: 10.1073/pnas.82.19.6657. [DOI] [PMC free article] [PubMed] [Google Scholar]
  510. Selsing E., Storb U. Somatic mutation of immunoglobulin light-chain variable-region genes. Cell. 1981 Jul;25(1):47–58. doi: 10.1016/0092-8674(81)90230-0. [DOI] [PubMed] [Google Scholar]
  511. Selten G., Cuypers H. T., Boelens W., Robanus-Maandag E., Verbeek J., Domen J., van Beveren C., Berns A. The primary structure of the putative oncogene pim-1 shows extensive homology with protein kinases. Cell. 1986 Aug 15;46(4):603–611. doi: 10.1016/0092-8674(86)90886-x. [DOI] [PubMed] [Google Scholar]
  512. Semon D., Kawashima E., Jongeneel C. V., Shakhov A. N., Nedospasov S. A. Nucleotide sequence of the murine TNF locus, including the TNF-alpha (tumor necrosis factor) and TNF-beta (lymphotoxin) genes. Nucleic Acids Res. 1987 Nov 11;15(21):9083–9084. doi: 10.1093/nar/15.21.9083. [DOI] [PMC free article] [PubMed] [Google Scholar]
  513. Servenius B., Gustafsson K., Widmark E., Emmoth E., Andersson G., Larhammar D., Rask L., Peterson P. A. Molecular map of the human HLA-SB (HLA-DP) region and sequence of an SB alpha (DP alpha) pseudogene. EMBO J. 1984 Dec 20;3(13):3209–3214. doi: 10.1002/j.1460-2075.1984.tb02280.x. [DOI] [PMC free article] [PubMed] [Google Scholar]
  514. Seto N. O., Hayashi S., Tener G. M. The sequence of the Cu-Zn superoxide dismutase gene of Drosophila. Nucleic Acids Res. 1987 Dec 23;15(24):10601–10601. doi: 10.1093/nar/15.24.10601. [DOI] [PMC free article] [PubMed] [Google Scholar]
  515. Shah D. M., Hightower R. C., Meagher R. B. Complete nucleotide sequence of a soybean actin gene. Proc Natl Acad Sci U S A. 1982 Feb;79(4):1022–1026. doi: 10.1073/pnas.79.4.1022. [DOI] [PMC free article] [PubMed] [Google Scholar]
  516. Shapiro M. B., Senapathy P. RNA splice junctions of different classes of eukaryotes: sequence statistics and functional implications in gene expression. Nucleic Acids Res. 1987 Sep 11;15(17):7155–7174. doi: 10.1093/nar/15.17.7155. [DOI] [PMC free article] [PubMed] [Google Scholar]
  517. Shapiro S. G., Schon E. A., Townes T. M., Lingrel J. B. Sequence and linkage of the goat epsilon I and epsilon II beta-globin genes. J Mol Biol. 1983 Sep 5;169(1):31–52. doi: 10.1016/s0022-2836(83)80174-0. [DOI] [PubMed] [Google Scholar]
  518. Shen S. H., Slightom J. L., Smithies O. A history of the human fetal globin gene duplication. Cell. 1981 Oct;26(2 Pt 2):191–203. doi: 10.1016/0092-8674(81)90302-0. [DOI] [PubMed] [Google Scholar]
  519. Sher B. T., Nairn R., Coligan J. E., Hood L. E. DNA sequence of the mouse H-2Dd transplantation antigen gene. Proc Natl Acad Sci U S A. 1985 Feb;82(4):1175–1179. doi: 10.1073/pnas.82.4.1175. [DOI] [PMC free article] [PubMed] [Google Scholar]
  520. Shibahara S., Morimoto Y., Furutani Y., Notake M., Takahashi H., Shimizu S., Horikawa S., Numa S. Isolation and sequence analysis of the human corticotropin-releasing factor precursor gene. EMBO J. 1983;2(5):775–779. doi: 10.1002/j.1460-2075.1983.tb01499.x. [DOI] [PMC free article] [PubMed] [Google Scholar]
  521. Shimasaki S., Koga M., Esch F., Cooksey K., Mercado M., Koba A., Ueno N., Ying S. Y., Ling N., Guillemin R. Primary structure of the human follistatin precursor and its genomic organization. Proc Natl Acad Sci U S A. 1988 Jun;85(12):4218–4222. doi: 10.1073/pnas.85.12.4218. [DOI] [PMC free article] [PubMed] [Google Scholar]
  522. Shine J., Dalgarno L. Determinant of cistron specificity in bacterial ribosomes. Nature. 1975 Mar 6;254(5495):34–38. doi: 10.1038/254034a0. [DOI] [PubMed] [Google Scholar]
  523. Shoemaker C. B., Mitsock L. D. Murine erythropoietin gene: cloning, expression, and human gene homology. Mol Cell Biol. 1986 Mar;6(3):849–858. doi: 10.1128/mcb.6.3.849. [DOI] [PMC free article] [PubMed] [Google Scholar]
  524. Shyu A. B., Blumenthal T., Raff R. A. A single gene encoding vitellogenin in the sea urchin Strongylocentrotus purpuratus: sequence at the 5' end. Nucleic Acids Res. 1987 Dec 23;15(24):10405–10417. doi: 10.1093/nar/15.24.10405. [DOI] [PMC free article] [PubMed] [Google Scholar]
  525. Siliciano P. G., Jones M. H., Guthrie C. Saccharomyces cerevisiae has a U1-like small nuclear RNA with unexpected properties. Science. 1987 Sep 18;237(4821):1484–1487. doi: 10.1126/science.3306922. [DOI] [PubMed] [Google Scholar]
  526. Simmen R. C., Tanaka T., Ts'ui K. F., Putkey J. A., Scott M. J., Lai E. C., Means A. R. The structural organization of the chicken calmodulin gene. J Biol Chem. 1985 Jan 25;260(2):907–912. [PubMed] [Google Scholar]
  527. Simmons D., Woollett G., Bergin-Cartwright M., Kay D., Scaife J. A malaria protein exported into a new compartment within the host erythrocyte. EMBO J. 1987 Feb;6(2):485–491. doi: 10.1002/j.1460-2075.1987.tb04779.x. [DOI] [PMC free article] [PubMed] [Google Scholar]
  528. Simon M., Seraphin B., Faye G. KIN28, a yeast split gene coding for a putative protein kinase homologous to CDC28. EMBO J. 1986 Oct;5(10):2697–2701. doi: 10.1002/j.1460-2075.1986.tb04553.x. [DOI] [PMC free article] [PubMed] [Google Scholar]
  529. Sittisombut N., Mordacq J., Knight K. L. Rabbit MHC. II. Sequence analysis of the R-DP alpha- and beta-genes. J Immunol. 1988 May 1;140(9):3237–3243. [PubMed] [Google Scholar]
  530. Slightom J. L., Blechl A. E., Smithies O. Human fetal G gamma- and A gamma-globin genes: complete nucleotide sequences suggest that DNA can be exchanged between these duplicated genes. Cell. 1980 Oct;21(3):627–638. doi: 10.1016/0092-8674(80)90426-2. [DOI] [PubMed] [Google Scholar]
  531. Slightom J. L., Chang L. Y., Koop B. F., Goodman M. Chimpanzee fetal G gamma and A gamma globin gene nucleotide sequences provide further evidence of gene conversions in hominine evolution. Mol Biol Evol. 1985 Sep;2(5):370–389. doi: 10.1093/oxfordjournals.molbev.a040357. [DOI] [PubMed] [Google Scholar]
  532. Slightom J. L., Theisen T. W., Koop B. F., Goodman M. Orangutan fetal globin genes. Nucleotide sequence reveal multiple gene conversions during hominid phylogeny. J Biol Chem. 1987 Jun 5;262(16):7472–7483. [PubMed] [Google Scholar]
  533. Smith D. J. The complete sequence of a frog alpha-tubulin gene and its regulated expression in mouse L-cells. Biochem J. 1988 Jan 15;249(2):465–472. doi: 10.1042/bj2490465. [DOI] [PMC free article] [PubMed] [Google Scholar]
  534. Smith H. A., Allaudeen H. S., Whitman M. H., Koltin Y., Gorman J. A. Isolation and characterization of a beta-tubulin gene from Candida albicans. Gene. 1988;63(1):53–63. doi: 10.1016/0378-1119(88)90545-8. [DOI] [PubMed] [Google Scholar]
  535. Smith T. L., Schalch H., Gaskell J., Covert S., Cullen D. Nucleotide sequence of a ligninase gene from Phanerochaete chrysosporium. Nucleic Acids Res. 1988 Feb 11;16(3):1219–1219. doi: 10.1093/nar/16.3.1219. [DOI] [PMC free article] [PubMed] [Google Scholar]
  536. Snutch T. P., Heschl M. F., Baillie D. L. The Caenorhabditis elegans hsp70 gene family: a molecular genetic characterization. Gene. 1988 Apr 29;64(2):241–255. doi: 10.1016/0378-1119(88)90339-3. [DOI] [PubMed] [Google Scholar]
  537. Soares M. B., Turken A., Ishii D., Mills L., Episkopou V., Cotter S., Zeitlin S., Efstratiadis A. Rat insulin-like growth factor II gene. A single gene with two promoters expressing a multitranscript family. J Mol Biol. 1986 Dec 20;192(4):737–752. doi: 10.1016/0022-2836(86)90025-2. [DOI] [PubMed] [Google Scholar]
  538. Sodoyer R., Damotte M., Delovitch T. L., Trucy J., Jordan B. R., Strachan T. Complete nucleotide sequence of a gene encoding a functional human class I histocompatibility antigen (HLA-CW3). EMBO J. 1984 Apr;3(4):879–885. doi: 10.1002/j.1460-2075.1984.tb01900.x. [DOI] [PMC free article] [PubMed] [Google Scholar]
  539. Sogawa K., Fujii-Kuriyama Y., Mizukami Y., Ichihara Y., Takahashi K. Primary structure of human pepsinogen gene. J Biol Chem. 1983 Apr 25;258(8):5306–5311. [PubMed] [Google Scholar]
  540. Sogawa K., Gotoh O., Kawajiri K., Harada T., Fujii-Kuriyama Y. Complete nucleotide sequence of a methylcholanthrene-inducible cytochrome P-450 (P-450d) gene in the rat. J Biol Chem. 1985 Apr 25;260(8):5026–5032. [PubMed] [Google Scholar]
  541. Soininen R., Tikka L., Chow L., Pihlajaniemi T., Kurkinen M., Prockop D. J., Boyd C. D., Tryggvason K. Large introns in the 3' end of the gene for the pro alpha 1 (IV) chain of human basement membrane collagen. Proc Natl Acad Sci U S A. 1986 Mar;83(6):1568–1572. doi: 10.1073/pnas.83.6.1568. [DOI] [PMC free article] [PubMed] [Google Scholar]
  542. Solnick D. An adenovirus mutant defective in splicing RNA from early region 1A. Nature. 1981 Jun 11;291(5815):508–510. doi: 10.1038/291508a0. [DOI] [PubMed] [Google Scholar]
  543. Sorger P. K., Pelham H. R. Cloning and expression of a gene encoding hsc73, the major hsp70-like protein in unstressed rat cells. EMBO J. 1987 Apr;6(4):993–998. doi: 10.1002/j.1460-2075.1987.tb04850.x. [DOI] [PMC free article] [PubMed] [Google Scholar]
  544. Spindel E. R., Zilberberg M. D., Chin W. W. Analysis of the gene and multiple messenger ribonucleic acids (mRNAs) encoding human gastrin-releasing peptide: alternate RNA splicing occurs in neural and endocrine tissue. Mol Endocrinol. 1987 Mar;1(3):224–232. doi: 10.1210/mend-1-3-224. [DOI] [PubMed] [Google Scholar]
  545. Spritz R. A., DeRiel J. K., Forget B. G., Weissman S. M. Complete nucleotide sequence of the human delta-globin gene. Cell. 1980 Oct;21(3):639–646. doi: 10.1016/0092-8674(80)90427-4. [DOI] [PubMed] [Google Scholar]
  546. Spritz R. A., Giebel L. B. The structure and evolution of the spider monkey delta-globin gene. Mol Biol Evol. 1988 Jan;5(1):21–29. doi: 10.1093/oxfordjournals.molbev.a040474. [DOI] [PubMed] [Google Scholar]
  547. Stanton L. W., Schwab M., Bishop J. M. Nucleotide sequence of the human N-myc gene. Proc Natl Acad Sci U S A. 1986 Mar;83(6):1772–1776. doi: 10.1073/pnas.83.6.1772. [DOI] [PMC free article] [PubMed] [Google Scholar]
  548. Stearman R. S., Lowell C. A., Peltzman C. G., Morrow J. F. The sequence and structure of a new serum amyloid A gene. Nucleic Acids Res. 1986 Jan 24;14(2):797–809. doi: 10.1093/nar/14.2.797. [DOI] [PMC free article] [PubMed] [Google Scholar]
  549. Steel L. F., Smyth A., Jacobson A. Nucleotide sequence and characterization of the transcript of a Dictyostelium ribosomal protein gene. Nucleic Acids Res. 1987 Dec 23;15(24):10285–10298. doi: 10.1093/nar/15.24.10285. [DOI] [PMC free article] [PubMed] [Google Scholar]
  550. Steen M. L., Hellman L., Pettersson U. Rat immunoglobulin E heavy chain locus. J Mol Biol. 1984 Jul 25;177(1):19–32. doi: 10.1016/0022-2836(84)90055-x. [DOI] [PubMed] [Google Scholar]
  551. Stein J. P., Catterall J. F., Kristo P., Means A. R., O'Malley B. W. Ovomucoid intervening sequences specify functional domains and generate protein polymorphism. Cell. 1980 Oct;21(3):681–687. doi: 10.1016/0092-8674(80)90431-6. [DOI] [PubMed] [Google Scholar]
  552. Steitz J. A., Jakes K. How ribosomes select initiator regions in mRNA: base pair formation between the 3' terminus of 16S rRNA and the mRNA during initiation of protein synthesis in Escherichia coli. Proc Natl Acad Sci U S A. 1975 Dec;72(12):4734–4738. doi: 10.1073/pnas.72.12.4734. [DOI] [PMC free article] [PubMed] [Google Scholar]
  553. Stenberg R. M., Witte P. R., Stinski M. F. Multiple spliced and unspliced transcripts from human cytomegalovirus immediate-early region 2 and evidence for a common initiation site within immediate-early region 1. J Virol. 1985 Dec;56(3):665–675. doi: 10.1128/jvi.56.3.665-675.1985. [DOI] [PMC free article] [PubMed] [Google Scholar]
  554. Stetler G., Brewer M. T., Thompson R. C. Isolation and sequence of a human gene encoding a potent inhibitor of leukocyte proteases. Nucleic Acids Res. 1986 Oct 24;14(20):7883–7896. doi: 10.1093/nar/14.20.7883. [DOI] [PMC free article] [PubMed] [Google Scholar]
  555. Stevenson B. J., Hagenbüchle O., Wellauer P. K. Sequence organisation and transcriptional regulation of the mouse elastase II and trypsin genes. Nucleic Acids Res. 1986 Nov 11;14(21):8307–8330. doi: 10.1093/nar/14.21.8307. [DOI] [PMC free article] [PubMed] [Google Scholar]
  556. Stewart A. G., Milborrow H. M., Ring J. M., Crowther C. E., Forage R. G. Human inhibin genes. Genomic characterisation and sequencing. FEBS Lett. 1986 Oct 6;206(2):329–334. doi: 10.1016/0014-5793(86)81006-7. [DOI] [PubMed] [Google Scholar]
  557. Stone E. M., Rothblum K. N., Alevy M. C., Kuo T. M., Schwartz R. J. Complete sequence of the chicken glyceraldehyde-3-phosphate dehydrogenase gene. Proc Natl Acad Sci U S A. 1985 Mar;82(6):1628–1632. doi: 10.1073/pnas.82.6.1628. [DOI] [PMC free article] [PubMed] [Google Scholar]
  558. Strachan T., Sodoyer R., Damotte M., Jordan B. R. Complete nucleotide sequence of a functional class I HLA gene, HLA-A3: implications for the evolution of HLA genes. EMBO J. 1984 Apr;3(4):887–894. doi: 10.1002/j.1460-2075.1984.tb01901.x. [DOI] [PMC free article] [PubMed] [Google Scholar]
  559. Strehler E. E., Strehler-Page M. A., Perriard J. C., Periasamy M., Nadal-Ginard B. Complete nucleotide and encoded amino acid sequence of a mammalian myosin heavy chain gene. Evidence against intron-dependent evolution of the rod. J Mol Biol. 1986 Aug 5;190(3):291–317. doi: 10.1016/0022-2836(86)90003-3. [DOI] [PubMed] [Google Scholar]
  560. Streuli M., Hall L. R., Saga Y., Schlossman S. F., Saito H. Differential usage of three exons generates at least five different mRNAs encoding human leukocyte common antigens. J Exp Med. 1987 Nov 1;166(5):1548–1566. doi: 10.1084/jem.166.5.1548. [DOI] [PMC free article] [PubMed] [Google Scholar]
  561. Sucov H. M., Benson S., Robinson J. J., Britten R. J., Wilt F., Davidson E. H. A lineage-specific gene encoding a major matrix protein of the sea urchin embryo spicule. II. Structure of the gene and derived sequence of the protein. Dev Biol. 1987 Apr;120(2):507–519. doi: 10.1016/0012-1606(87)90254-5. [DOI] [PubMed] [Google Scholar]
  562. Sullivan K. F., Machlin P. S., Ratrie H., 3rd, Cleveland D. W. Sequence and expression of the chicken beta 3 tubulin gene. A vertebrate testis beta-tubulin isotype. J Biol Chem. 1986 Oct 5;261(28):13317–13322. [PubMed] [Google Scholar]
  563. Suminami Y., Kishi F., Torigoe T., Nakazawa A. Structure and complete nucleotide sequence of the gene encoding chicken cytosolic adenylate kinase. J Biochem. 1988 Apr;103(4):611–617. doi: 10.1093/oxfordjournals.jbchem.a122315. [DOI] [PubMed] [Google Scholar]
  564. Suske G., Wenz M., Cato A. C., Beato M. The uteroglobin gene region: hormonal regulation, repetitive elements and complete nucleotide sequence of the gene. Nucleic Acids Res. 1983 Apr 25;11(8):2257–2271. doi: 10.1093/nar/11.8.2257. [DOI] [PMC free article] [PubMed] [Google Scholar]
  565. Suter U., Bastos R., Hofstetter H. Molecular structure of the gene and the 5'-flanking region of the human lymphocyte immunoglobulin E receptor. Nucleic Acids Res. 1987 Sep 25;15(18):7295–7308. doi: 10.1093/nar/15.18.7295. [DOI] [PMC free article] [PubMed] [Google Scholar]
  566. Suwa Y., Mizukami Y., Sogawa K., Fujii-Kuriyama Y. Gene structure of a major form of phenobarbital-inducible cytochrome P-450 in rat liver. J Biol Chem. 1985 Jul 5;260(13):7980–7984. [PubMed] [Google Scholar]
  567. Suzuki K., Otaka E. Cloning and nucleotide sequence of the gene encoding yeast ribosomal protein YS25. Nucleic Acids Res. 1988 Jul 11;16(13):6223–6223. doi: 10.1093/nar/16.13.6223. [DOI] [PMC free article] [PubMed] [Google Scholar]
  568. Sweetser D. A., Birkenmeier E. H., Klisak I. J., Zollman S., Sparkes R. S., Mohandas T., Lusis A. J., Gordon J. I. The human and rodent intestinal fatty acid binding protein genes. A comparative analysis of their structure, expression, and linkage relationships. J Biol Chem. 1987 Nov 25;262(33):16060–16071. [PubMed] [Google Scholar]
  569. Sweetser D. A., Lowe J. B., Gordon J. I. The nucleotide sequence of the rat liver fatty acid-binding protein gene. Evidence that exon 1 encodes an oligopeptide domain shared by a family of proteins which bind hydrophobic ligands. J Biol Chem. 1986 Apr 25;261(12):5553–5561. [PubMed] [Google Scholar]
  570. Swift G. H., Craik C. S., Stary S. J., Quinto C., Lahaie R. G., Rutter W. J., MacDonald R. J. Structure of the two related elastase genes expressed in the rat pancreas. J Biol Chem. 1984 Nov 25;259(22):14271–14278. [PubMed] [Google Scholar]
  571. Südhof T. C., Goldstein J. L., Brown M. S., Russell D. W. The LDL receptor gene: a mosaic of exons shared with different proteins. Science. 1985 May 17;228(4701):815–822. doi: 10.1126/science.2988123. [DOI] [PMC free article] [PubMed] [Google Scholar]
  572. Takahashi H., Hakamata Y., Watanabe Y., Kikuno R., Miyata T., Numa S. Complete nucleotide sequence of the human corticotropin-beta-lipotropin precursor gene. Nucleic Acids Res. 1983 Oct 11;11(19):6847–6858. doi: 10.1093/nar/11.19.6847. [DOI] [PMC free article] [PubMed] [Google Scholar]
  573. Takahashi N., Noma T., Honjo T. Rearranged immunoglobulin heavy chain variable region (VH) pseudogene that deletes the second complementarity-determining region. Proc Natl Acad Sci U S A. 1984 Aug;81(16):5194–5198. doi: 10.1073/pnas.81.16.5194. [DOI] [PMC free article] [PubMed] [Google Scholar]
  574. Takahashi N., Roach A., Teplow D. B., Prusiner S. B., Hood L. Cloning and characterization of the myelin basic protein gene from mouse: one gene can encode both 14 kd and 18.5 kd MBPs by alternate use of exons. Cell. 1985 Aug;42(1):139–148. doi: 10.1016/s0092-8674(85)80109-4. [DOI] [PubMed] [Google Scholar]
  575. Takahashi Y., Kato K., Hayashizaki Y., Wakabayashi T., Ohtsuka E., Matsuki S., Ikehara M., Matsubara K. Molecular cloning of the human cholecystokinin gene by use of a synthetic probe containing deoxyinosine. Proc Natl Acad Sci U S A. 1985 Apr;82(7):1931–1935. doi: 10.1073/pnas.82.7.1931. [DOI] [PMC free article] [PubMed] [Google Scholar]
  576. Takeshima H., Joh T., Tsuzuki T., Shimada K., Matsukado Y. Structural organization of the mouse mitochondrial malate dehydrogenase gene. J Mol Biol. 1988 Mar 5;200(1):1–11. doi: 10.1016/0022-2836(88)90328-2. [DOI] [PubMed] [Google Scholar]
  577. Takiguchi M., Murakami T., Miura S., Mori M. Structure of the rat ornithine carbamoyltransferase gene, a large, X chromosome-linked gene with an atypical promoter. Proc Natl Acad Sci U S A. 1987 Sep;84(17):6136–6140. doi: 10.1073/pnas.84.17.6136. [DOI] [PMC free article] [PubMed] [Google Scholar]
  578. Tal M., King C. R., Kraus M. H., Ullrich A., Schlessinger J., Givol D. Human HER2 (neu) promoter: evidence for multiple mechanisms for transcriptional initiation. Mol Cell Biol. 1987 Jul;7(7):2597–2601. doi: 10.1128/mcb.7.7.2597. [DOI] [PMC free article] [PubMed] [Google Scholar]
  579. Talmadge K., Vamvakopoulos N. C., Fiddes J. C. Evolution of the genes for the beta subunits of human chorionic gonadotropin and luteinizing hormone. Nature. 1984 Jan 5;307(5946):37–40. doi: 10.1038/307037a0. [DOI] [PubMed] [Google Scholar]
  580. Tam Y. C., Chopra A., Hassan M., Thirion J. P. Cloning, nucleotide sequence and characterization of a New Zealand rabbit metallothionein-I gene. Biochem Biophys Res Commun. 1988 May 31;153(1):209–216. doi: 10.1016/s0006-291x(88)81210-5. [DOI] [PubMed] [Google Scholar]
  581. Tanabe T., Konishi M., Mizuta T., Noma T., Honjo T. Molecular cloning and structure of the human interleukin-5 gene. J Biol Chem. 1987 Dec 5;262(34):16580–16584. [PubMed] [Google Scholar]
  582. Tani T., Ohsumi J., Mita K., Takiguchi Y. Identification of a novel class of elastase isozyme, human pancreatic elastase III, by cDNA and genomic gene cloning. J Biol Chem. 1988 Jan 25;263(3):1231–1239. [PubMed] [Google Scholar]
  583. Tate V. E., Finer M. H., Boedtker H., Doty P. Chick pro alpha 2 (I) collagen gene: exon location and coding potential for the prepropeptide. Nucleic Acids Res. 1983 Jan 11;11(1):91–104. doi: 10.1093/nar/11.1.91. [DOI] [PMC free article] [PubMed] [Google Scholar]
  584. Teem J. L., Rosbash M. Expression of a beta-galactosidase gene containing the ribosomal protein 51 intron is sensitive to the rna2 mutation of yeast. Proc Natl Acad Sci U S A. 1983 Jul;80(14):4403–4407. doi: 10.1073/pnas.80.14.4403. [DOI] [PMC free article] [PubMed] [Google Scholar]
  585. Telford J. L., Macchia G., Massone A., Carinci V., Palla E., Melli M. The murine interleukin 1 beta gene: structure and evolution. Nucleic Acids Res. 1986 Dec 22;14(24):9955–9963. doi: 10.1093/nar/14.24.9955. [DOI] [PMC free article] [PubMed] [Google Scholar]
  586. Thompson M. A., Hawkins J. W., Piatigorsky J. Complete nucleotide sequence of the chicken alpha A-crystallin gene and its 5' flanking region. Gene. 1987;56(2-3):173–184. doi: 10.1016/0378-1119(87)90135-1. [DOI] [PubMed] [Google Scholar]
  587. Todokoro K., Yamamoto A., Amanuma H., Ikawa Y. Isolation and characterization of a genomic DDD mouse interleukin-3 gene. Gene. 1985;39(1):103–107. doi: 10.1016/0378-1119(85)90114-3. [DOI] [PubMed] [Google Scholar]
  588. Tonegawa S., Maxam A. M., Tizard R., Bernard O., Gilbert W. Sequence of a mouse germ-line gene for a variable region of an immunoglobulin light chain. Proc Natl Acad Sci U S A. 1978 Mar;75(3):1485–1489. doi: 10.1073/pnas.75.3.1485. [DOI] [PMC free article] [PubMed] [Google Scholar]
  589. Treisman R., Orkin S. H., Maniatis T. Specific transcription and RNA splicing defects in five cloned beta-thalassaemia genes. Nature. 1983 Apr 14;302(5909):591–596. doi: 10.1038/302591a0. [DOI] [PubMed] [Google Scholar]
  590. Triglia T., Stahl H. D., Crewther P. E., Scanlon D., Brown G. V., Anders R. F., Kemp D. J. The complete sequence of the gene for the knob-associated histidine-rich protein from Plasmodium falciparum. EMBO J. 1987 May;6(5):1413–1419. doi: 10.1002/j.1460-2075.1987.tb02382.x. [DOI] [PMC free article] [PubMed] [Google Scholar]
  591. Trowsdale J., Kelly A. The human HLA class II alpha chain gene DZ alpha is distinct from genes in the DP, DQ and DR subregions. EMBO J. 1985 Sep;4(9):2231–2237. doi: 10.1002/j.1460-2075.1985.tb03919.x. [DOI] [PMC free article] [PubMed] [Google Scholar]
  592. Truong A. T., Duez C., Belayew A., Renard A., Pictet R., Bell G. I., Martial J. A. Isolation and characterization of the human prolactin gene. EMBO J. 1984 Feb;3(2):429–437. doi: 10.1002/j.1460-2075.1984.tb01824.x. [DOI] [PMC free article] [PubMed] [Google Scholar]
  593. Tsao Y. K., Wei C. F., Robberson D. L., Gotto A. M., Jr, Chan L. Isolation and characterization of the human apolipoprotein A-II gene. Electron microscopic analysis of RNA:DNA hybrids, nucleotide sequence, identification of a polymorphic MspI site, and general structural organization of apolipoprotein genes. J Biol Chem. 1985 Dec 5;260(28):15222–15231. [PubMed] [Google Scholar]
  594. Tso J. Y., Van Den Berg D. J., Korn L. J. Structure of the gene for Xenopus transcription factor TFIIIA. Nucleic Acids Res. 1986 Mar 11;14(5):2187–2200. doi: 10.1093/nar/14.5.2187. [DOI] [PMC free article] [PubMed] [Google Scholar]
  595. Tsujimoto Y., Suzuki Y. The DNA sequence of Bombyx mori fibroin gene including the 5' flanking, mRNA coding, entire intervening and fibroin protein coding regions. Cell. 1979 Oct;18(2):591–600. doi: 10.1016/0092-8674(79)90075-8. [DOI] [PubMed] [Google Scholar]
  596. Tucker P. W., Liu C. P., Mushinski J. F., Blattner F. R. Mouse immunoglobulin D: messenger RNA and genomic DNA sequences. Science. 1980 Sep 19;209(4463):1353–1360. doi: 10.1126/science.6968091. [DOI] [PubMed] [Google Scholar]
  597. Tucker P. W., Marcu K. B., Newell N., Richards J., Blattner F. R. Sequence of the cloned gene for the constant region of murine gamma 2b immunoglobulin heavy chain. Science. 1979 Dec 14;206(4424):1303–1306. doi: 10.1126/science.117549. [DOI] [PubMed] [Google Scholar]
  598. Tumer N. E., Clark W. G., Tabor G. J., Hironaka C. M., Fraley R. T., Shah D. M. The genes encoding the small subunit of ribulose-1,5-bisphosphate carboxylase are expressed differentially in petunia leaves. Nucleic Acids Res. 1986 Apr 25;14(8):3325–3342. doi: 10.1093/nar/14.8.3325. [DOI] [PMC free article] [PubMed] [Google Scholar]
  599. Uemura T., Morino K., Uzawa S., Shiozaki K., Yanagida M. Cloning and sequencing of Schizosaccharomyces pombe DNA topoisomerase I gene, and effect of gene disruption. Nucleic Acids Res. 1987 Dec 10;15(23):9727–9739. doi: 10.1093/nar/15.23.9727. [DOI] [PMC free article] [PubMed] [Google Scholar]
  600. Ueno T., Takahashi K., Matsuguchi T., Endo H., Yamamoto M. A new leader exon identified in the rat insulin-like growth factor II gene. Biochem Biophys Res Commun. 1987 Oct 14;148(1):344–349. doi: 10.1016/0006-291x(87)91116-8. [DOI] [PubMed] [Google Scholar]
  601. Ullrich A., Gray A., Berman C., Dull T. J. Human beta-nerve growth factor gene sequence highly homologous to that of mouse. Nature. 1983 Jun 30;303(5920):821–825. doi: 10.1038/303821a0. [DOI] [PubMed] [Google Scholar]
  602. Umeno M., Song B. J., Kozak C., Gelboin H. V., Gonzalez F. J. The rat P450IIE1 gene: complete intron and exon sequence, chromosome mapping, and correlation of developmental expression with specific 5' cytosine demethylation. J Biol Chem. 1988 Apr 5;263(10):4956–4962. [PubMed] [Google Scholar]
  603. Venta P. J., Montgomery J. C., Hewett-Emmett D., Wiebauer K., Tashian R. E. Structure and exon to protein domain relationships of the mouse carbonic anhydrase II gene. J Biol Chem. 1985 Oct 5;260(22):12130–12135. [PubMed] [Google Scholar]
  604. Virbasius J. V., Scarpulla R. C. Structure and expression of rodent genes encoding the testis-specific cytochrome c. Differences in gene structure and evolution between somatic and testicular variants. J Biol Chem. 1988 May 15;263(14):6791–6796. [PubMed] [Google Scholar]
  605. Virgin J. B., Silver B. J., Thomason A. R., Nilson J. H. The gene for the beta subunit of bovine luteinizing hormone encodes a gonadotropin mRNA with an unusually short 5'-untranslated region. J Biol Chem. 1985 Jun 10;260(11):7072–7077. [PubMed] [Google Scholar]
  606. Vlasak R., Wiborg O., Richter K., Burgschwaiger S., Vuust J., Kreil G. Conserved exon-intron organization in two different caerulein precursor genes of Xenopus laevis. Additional detection of an exon potentially coding for a new peptide. Eur J Biochem. 1987 Nov 16;169(1):53–58. doi: 10.1111/j.1432-1033.1987.tb13579.x. [DOI] [PubMed] [Google Scholar]
  607. Wassenberg D. R., 2nd, Kronert W. A., O'Donnell P. T., Bernstein S. I. Analysis of the 5' end of the Drosophila muscle myosin heavy chain gene. Alternatively spliced transcripts initiate at a single site and intron locations are conserved compared to myosin genes of other organisms. J Biol Chem. 1987 Aug 5;262(22):10741–10747. [PubMed] [Google Scholar]
  608. Watts F., Castle C., Beggs J. Aberrant splicing of Drosophila alcohol dehydrogenase transcripts in Saccharomyces cerevisiae. EMBO J. 1983;2(11):2085–2091. doi: 10.1002/j.1460-2075.1983.tb01704.x. [DOI] [PMC free article] [PubMed] [Google Scholar]
  609. Ways J. P., Coppin H. L., Parham P. The complete primary structure of HLA-Bw58. J Biol Chem. 1985 Oct 5;260(22):11924–11933. [PubMed] [Google Scholar]
  610. Weber S., Aebi M. In vitro splicing of mRNA precursors: 5' cleavage site can be predicted from the interaction between the 5' splice region and the 5' terminus of U1 snRNA. Nucleic Acids Res. 1988 Jan 25;16(2):471–486. doi: 10.1093/nar/16.2.471. [DOI] [PMC free article] [PubMed] [Google Scholar]
  611. Wei C. F., Tsao Y. K., Robberson D. L., Gotto A. M., Jr, Brown K., Chan L. The structure of the human apolipoprotein C-II gene. Electron microscopic analysis of RNA:DNA hybrids, complete nucleotide sequence, and identification of 5' homologous sequences among apolipoprotein genes. J Biol Chem. 1985 Dec 5;260(28):15211–15221. [PubMed] [Google Scholar]
  612. Weil D., Bernard M., Combates N., Wirtz M. K., Hollister D. W., Steinmann B., Ramirez F. Identification of a mutation that causes exon skipping during collagen pre-mRNA splicing in an Ehlers-Danlos syndrome variant. J Biol Chem. 1988 Jun 25;263(18):8561–8564. [PubMed] [Google Scholar]
  613. Weinstein L. S., Spiegel A. M., Carter A. D. Cloning and characterization of the human gene for the alpha-subunit of Gi2, a GTP-binding signal transduction protein. FEBS Lett. 1988 May 23;232(2):333–340. doi: 10.1016/0014-5793(88)80764-6. [DOI] [PubMed] [Google Scholar]
  614. Weiss E. H., Cheah K. S., Grosveld F. G., Dahl H. H., Solomon E., Flavell R. A. Isolation and characterization of a human collagen alpha 1(I)-like gene from a cosmid library. Nucleic Acids Res. 1982 Mar 25;10(6):1981–1994. doi: 10.1093/nar/10.6.1981. [DOI] [PMC free article] [PubMed] [Google Scholar]
  615. Weiss M. J., Ray K., Henthorn P. S., Lamb B., Kadesch T., Harris H. Structure of the human liver/bone/kidney alkaline phosphatase gene. J Biol Chem. 1988 Aug 25;263(24):12002–12010. [PubMed] [Google Scholar]
  616. Weller P., Jeffreys A. J., Wilson V., Blanchetot A. Organization of the human myoglobin gene. EMBO J. 1984 Feb;3(2):439–446. doi: 10.1002/j.1460-2075.1984.tb01825.x. [DOI] [PMC free article] [PubMed] [Google Scholar]
  617. Wells D., Hoffman D., Kedes L. Unusual structure, evolutionary conservation of non-coding sequences and numerous pseudogenes characterize the human H3.3 histone multigene family. Nucleic Acids Res. 1987 Apr 10;15(7):2871–2889. doi: 10.1093/nar/15.7.2871. [DOI] [PMC free article] [PubMed] [Google Scholar]
  618. Wels J. A., Word C. J., Rimm D., Der-Balan G. P., Martinez H. M., Tucker P. W., Blattner F. R. Structural analysis of the murine IgG3 constant region gene. EMBO J. 1984 Sep;3(9):2041–2046. doi: 10.1002/j.1460-2075.1984.tb02089.x. [DOI] [PMC free article] [PubMed] [Google Scholar]
  619. Werenskiold A. K., Poetsch B., Haugli F. Cloning and expression of a beta tubulin gene of Physarum polycephalum. Eur J Biochem. 1988 Jun 15;174(3):491–495. doi: 10.1111/j.1432-1033.1988.tb14125.x. [DOI] [PubMed] [Google Scholar]
  620. Werr W., Frommer W. B., Maas C., Starlinger P. Structure of the sucrose synthase gene on chromosome 9 of Zea mays L. EMBO J. 1985 Jun;4(6):1373–1380. doi: 10.1002/j.1460-2075.1985.tb03789.x. [DOI] [PMC free article] [PubMed] [Google Scholar]
  621. Weschke W., Bäumlein H., Wobus U. Nucleotide sequence of a field bean (Vicia faba L.var.minor) vicilin gene. Nucleic Acids Res. 1987 Dec 10;15(23):10065–10065. doi: 10.1093/nar/15.23.10065. [DOI] [PMC free article] [PubMed] [Google Scholar]
  622. Wharton K. A., Yedvobnick B., Finnerty V. G., Artavanis-Tsakonas S. opa: a novel family of transcribed repeats shared by the Notch locus and other developmentally regulated loci in D. melanogaster. Cell. 1985 Jan;40(1):55–62. doi: 10.1016/0092-8674(85)90308-3. [DOI] [PubMed] [Google Scholar]
  623. White J. W., Saunders G. F. Structure of the human glucagon gene. Nucleic Acids Res. 1986 Jun 25;14(12):4719–4730. doi: 10.1093/nar/14.12.4719. [DOI] [PMC free article] [PubMed] [Google Scholar]
  624. White M. B., Shen A. L., Word C. J., Tucker P. W., Blattner F. R. Human immunoglobulin D: genomic sequence of the delta heavy chain. Science. 1985 May 10;228(4700):733–737. doi: 10.1126/science.3922054. [DOI] [PubMed] [Google Scholar]
  625. Whittier R. F., Dean D. A., Rogers J. C. Nucleotide sequence analysis of alpha-amylase and thiol protease genes that are hormonally regulated in barley aleurone cells. Nucleic Acids Res. 1987 Mar 25;15(6):2515–2535. doi: 10.1093/nar/15.6.2515. [DOI] [PMC free article] [PubMed] [Google Scholar]
  626. Wiborg O., Berglund L., Boel E., Norris F., Norris K., Rehfeld J. F., Marcker K. A., Vuust J. Structure of a human gastrin gene. Proc Natl Acad Sci U S A. 1984 Feb;81(4):1067–1069. doi: 10.1073/pnas.81.4.1067. [DOI] [PMC free article] [PubMed] [Google Scholar]
  627. Wiborg O., Hyldig-Nielsen J. J., Jensen E. O., Paludan K., Marcker K. A. The nucleotide sequences of two leghemoglobin genes from soybean. Nucleic Acids Res. 1982 Jun 11;10(11):3487–3494. doi: 10.1093/nar/10.11.3487. [DOI] [PMC free article] [PubMed] [Google Scholar]
  628. Wiginton D. A., Kaplan D. J., States J. C., Akeson A. L., Perme C. M., Bilyk I. J., Vaughn A. J., Lattier D. L., Hutton J. J. Complete sequence and structure of the gene for human adenosine deaminase. Biochemistry. 1986 Dec 16;25(25):8234–8244. doi: 10.1021/bi00373a017. [DOI] [PubMed] [Google Scholar]
  629. Wildeman A. G. A putative ancestral actin gene present in a thermophilic eukaryote: novel combination of intron positions. Nucleic Acids Res. 1988 Mar 25;16(6):2553–2564. doi: 10.1093/nar/16.6.2553. [DOI] [PMC free article] [PubMed] [Google Scholar]
  630. Williams S. C., Bruckheimer S. M., Lusis A. J., LeBoeuf R. C., Kinniburgh A. J. Mouse apolipoprotein A-IV gene: nucleotide sequence and induction by a high-lipid diet. Mol Cell Biol. 1986 Nov;6(11):3807–3814. doi: 10.1128/mcb.6.11.3807. [DOI] [PMC free article] [PubMed] [Google Scholar]
  631. Wilson L. J., Carmona C. L., Ward M. Sequence of the Aspergillus niger pyrG gene. Nucleic Acids Res. 1988 Mar 25;16(5):2339–2339. doi: 10.1093/nar/16.5.2339. [DOI] [PMC free article] [PubMed] [Google Scholar]
  632. Wilson P. W., Rogers J., Harding M., Pohl V., Pattyn G., Lawson D. E. Structure of chick chromosomal genes for calbindin and calretinin. J Mol Biol. 1988 Apr 20;200(4):615–625. doi: 10.1016/0022-2836(88)90475-5. [DOI] [PubMed] [Google Scholar]
  633. Winoto A., Mjolsness S., Hood L. Genomic organization of the genes encoding mouse T-cell receptor alpha-chain. 1985 Aug 29-Sep 4Nature. 316(6031):832–836. doi: 10.1038/316832a0. [DOI] [PubMed] [Google Scholar]
  634. Wolf O., Kourides I. A., Gurr J. A. Expression of the gene for the beta subunit of mouse thyrotropin results in multiple mRNAs differing in their 5'-untranslated regions. J Biol Chem. 1987 Dec 5;262(34):16596–16603. [PubMed] [Google Scholar]
  635. Wong W. M., Lam V. M., Cheng L. Y., Tam J. W. Genomic sequence of a Sprague-Dawley rat beta-globin gene. Nucleic Acids Res. 1988 Mar 25;16(5):2342–2342. doi: 10.1093/nar/16.5.2342. [DOI] [PMC free article] [PubMed] [Google Scholar]
  636. Woo P., Korenberg J. R., Whitehead A. S. Characterization of genomic and complementary DNA sequence of human C-reactive protein, and comparison with the complementary DNA sequence of serum amyloid P component. J Biol Chem. 1985 Oct 25;260(24):13384–13388. [PubMed] [Google Scholar]
  637. Woo P., Sipe J., Dinarello C. A., Colten H. R. Structure of a human serum amyloid A gene and modulation of its expression in transfected L cells. J Biol Chem. 1987 Nov 15;262(32):15790–15795. [PubMed] [Google Scholar]
  638. Woo S. L., Beattie W. G., Catterall J. F., Dugaiczyk A., Staden R., Brownlee G. G., O'Malley B. W. Complete nucleotide sequence of the chicken chromosomal ovalbumin gene and its biological significance. Biochemistry. 1981 Oct 27;20(22):6437–6446. doi: 10.1021/bi00525a024. [DOI] [PubMed] [Google Scholar]
  639. Woudt L. P., Pastink A., Kempers-Veenstra A. E., Jansen A. E., Mager W. H., Planta R. J. The genes coding for histone H3 and H4 in Neurospora crassa are unique and contain intervening sequences. Nucleic Acids Res. 1983 Aug 25;11(16):5347–5360. doi: 10.1093/nar/11.16.5347. [DOI] [PMC free article] [PubMed] [Google Scholar]
  640. Woychik R. P., Camper S. A., Lyons R. H., Horowitz S., Goodwin E. C., Rottman F. M. Cloning and nucleotide sequencing of the bovine growth hormone gene. Nucleic Acids Res. 1982 Nov 25;10(22):7197–7210. doi: 10.1093/nar/10.22.7197. [DOI] [PMC free article] [PubMed] [Google Scholar]
  641. Wozney J., Hanahan D., Tate V., Boedtker H., Doty P. Structure of the pro alpha 2 (I) collagen gene. Nature. 1981 Nov 12;294(5837):129–135. doi: 10.1038/294129a0. [DOI] [PubMed] [Google Scholar]
  642. Wu G. E., Hozumi N., Murialdo H. Secretion of a lambda 2 immunoglobulin chain is prevented by a single amino acid substitution in its variable region. Cell. 1983 May;33(1):77–83. doi: 10.1016/0092-8674(83)90336-7. [DOI] [PubMed] [Google Scholar]
  643. Xanthopoulos K. G., Lee J. Y., Gan R., Kockum K., Faye I., Boman H. G. The structure of the gene for cecropin B, an antibacterial immune protein from Hyalophora cecropia. Eur J Biochem. 1988 Mar 1;172(2):371–376. doi: 10.1111/j.1432-1033.1988.tb13896.x. [DOI] [PubMed] [Google Scholar]
  644. Yamada Y., Avvedimento V. E., Mudryj M., Ohkubo H., Vogeli G., Irani M., Pastan I., de Crombrugghe B. The collagen gene: evidence for its evolutinary assembly by amplification of a DNA segment containing an exon of 54 bp. Cell. 1980 Dec;22(3):887–892. doi: 10.1016/0092-8674(80)90565-6. [DOI] [PubMed] [Google Scholar]
  645. Yamada Y., Kühn K., de Crombrugghe B. A conserved nucleotide sequence, coding for a segment of the C-propeptide, is found at the same location in different collagen genes. Nucleic Acids Res. 1983 May 11;11(9):2733–2744. doi: 10.1093/nar/11.9.2733. [DOI] [PMC free article] [PubMed] [Google Scholar]
  646. Yamada Y., Liau G., Mudryj M., Obici S., de Crombrugghe B. Conservation of the sizes for one but not another class of exons in two chick collagen genes. 1984 Jul 26-Aug 1Nature. 310(5975):333–337. doi: 10.1038/310333a0. [DOI] [PubMed] [Google Scholar]
  647. Yamawaki-Kataoka Y., Kataoka T., Takahashi N., Obata M., Honjo T. Complete nucleotide sequence of immunoglobulin gamma2b chain gene cloned from newborn nouse DNA. Nature. 1980 Feb 21;283(5749):786–789. doi: 10.1038/283786a0. [DOI] [PubMed] [Google Scholar]
  648. Yamawaki-Kataoka Y., Miyata T., Honjo T. The complete nucleotide sequence of mouse immunoglobin gamma 2a gene and evolution of heavy chain genes: further evidence for intervening sequence-mediated domain transfer. Nucleic Acids Res. 1981 Mar 25;9(6):1365–1381. doi: 10.1093/nar/9.6.1365. [DOI] [PMC free article] [PubMed] [Google Scholar]
  649. Yamawaki-Kataoka Y., Nakai S., Miyata T., Honjo T. Nucleotide sequences of gene segments encoding membrane domains of immunoglobulin gamma chains. Proc Natl Acad Sci U S A. 1982 Apr;79(8):2623–2627. doi: 10.1073/pnas.79.8.2623. [DOI] [PMC free article] [PubMed] [Google Scholar]
  650. Yasuda K., Nakajima N., Isobe T., Okada T. S., Shimura Y. The nucleotide sequence of a complete chicken delta-crystallin cDNA. EMBO J. 1984 Jun;3(6):1397–1402. doi: 10.1002/j.1460-2075.1984.tb01983.x. [DOI] [PMC free article] [PubMed] [Google Scholar]
  651. Yoshihara C. M., Lee J. D., Dodgson J. B. The chicken carbonic anhydrase II gene: evidence for a recent shift in intron position. Nucleic Acids Res. 1987 Jan 26;15(2):753–770. doi: 10.1093/nar/15.2.753. [DOI] [PMC free article] [PubMed] [Google Scholar]
  652. Yoshikai Y., Clark S. P., Taylor S., Sohn U., Wilson B. I., Minden M. D., Mak T. W. Organization and sequences of the variable, joining and constant region genes of the human T-cell receptor alpha-chain. 1985 Aug 29-Sep 4Nature. 316(6031):837–840. doi: 10.1038/316837a0. [DOI] [PubMed] [Google Scholar]
  653. Yoshitake S., Schach B. G., Foster D. C., Davie E. W., Kurachi K. Nucleotide sequence of the gene for human factor IX (antihemophilic factor B). Biochemistry. 1985 Jul 2;24(14):3736–3750. doi: 10.1021/bi00335a049. [DOI] [PubMed] [Google Scholar]
  654. Yu-Lee L. Y., Rosen J. M. The rat casein multigene family. I. Fine structure of the gamma-casein gene. J Biol Chem. 1983 Sep 10;258(17):10794–10804. [PubMed] [Google Scholar]
  655. Zahraoui A., Cuny G. Nucleotide sequence of the chicken proto-oncogene c-erbA corresponding to domain 1 of v-erbA. Eur J Biochem. 1987 Jul 1;166(1):63–69. doi: 10.1111/j.1432-1033.1987.tb13484.x. [DOI] [PubMed] [Google Scholar]
  656. Zakut R., Shani M., Givol D., Neuman S., Yaffe D., Nudel U. Nucleotide sequence of the rat skeletal muscle actin gene. Nature. 1982 Aug 26;298(5877):857–859. doi: 10.1038/298857a0. [DOI] [PubMed] [Google Scholar]
  657. Zehner Z. E., Li Y., Roe B. A., Paterson B. M., Sax C. M. The chicken vimentin gene. Nucleotide sequence, regulatory elements, and comparison to the hamster gene. J Biol Chem. 1987 Jun 15;262(17):8112–8120. [PubMed] [Google Scholar]
  658. Zhang K., Bosron W. F., Edenberg H. J. Structure of the mouse Adh-1 gene and identification of a deletion in a long alternating purine-pyrimidine sequence in the first intron of strains expressing low alcohol dehydrogenase activity. Gene. 1987;57(1):27–36. doi: 10.1016/0378-1119(87)90173-9. [DOI] [PubMed] [Google Scholar]
  659. Zhao D. B., Côté S., Jähnig F., Haller J., Jäckle H. Zipper encodes a putative integral membrane protein required for normal axon patterning during Drosophila neurogenesis. EMBO J. 1988 Apr;7(4):1115–1119. doi: 10.1002/j.1460-2075.1988.tb02920.x. [DOI] [PMC free article] [PubMed] [Google Scholar]
  660. de Wet J. R., Wood K. V., DeLuca M., Helinski D. R., Subramani S. Firefly luciferase gene: structure and expression in mammalian cells. Mol Cell Biol. 1987 Feb;7(2):725–737. doi: 10.1128/mcb.7.2.725. [DOI] [PMC free article] [PubMed] [Google Scholar]
  661. den Dunnen J. T., Moormann R. J., Lubsen N. H., Schoenmakers J. G. Intron insertions and deletions in the beta/gamma-crystallin gene family: the rat beta B1 gene. Proc Natl Acad Sci U S A. 1986 May;83(9):2855–2859. doi: 10.1073/pnas.83.9.2855. [DOI] [PMC free article] [PubMed] [Google Scholar]
  662. van Leeuwen B. H., Evans B. A., Tregear G. W., Richards R. I. Mouse glandular kallikrein genes. Identification, structure, and expression of the renal kallikrein gene. J Biol Chem. 1986 Apr 25;261(12):5529–5535. [PubMed] [Google Scholar]
  663. van Ooyen A., Kwee V., Nusse R. The nucleotide sequence of the human int-1 mammary oncogene; evolutionary conservation of coding and non-coding sequences. EMBO J. 1985 Nov;4(11):2905–2909. doi: 10.1002/j.1460-2075.1985.tb04021.x. [DOI] [PMC free article] [PubMed] [Google Scholar]
  664. van Ooyen A., Nusse R. Structure and nucleotide sequence of the putative mammary oncogene int-1; proviral insertions leave the protein-encoding domain intact. Cell. 1984 Nov;39(1):233–240. doi: 10.1016/0092-8674(84)90209-5. [DOI] [PubMed] [Google Scholar]
  665. van Santen V. L., Spritz R. A. Nucleotide sequence of a bean (Phaseolus vulgaris) U1 small nuclear RNA gene: implications for plant pre-mRNA splicing. Proc Natl Acad Sci U S A. 1987 Dec;84(24):9094–9098. doi: 10.1073/pnas.84.24.9094. [DOI] [PMC free article] [PubMed] [Google Scholar]
  666. van Santen V. L., Spritz R. A. Splicing of plant pre-mRNAs in animal systems and vice versa. Gene. 1987;56(2-3):253–265. doi: 10.1016/0378-1119(87)90142-9. [DOI] [PubMed] [Google Scholar]
  667. van Santen V. L., Swain W., Spritz R. A. Nucleotide sequences of two soybean U1 snRNA genes. Nucleic Acids Res. 1988 May 11;16(9):4176–4176. doi: 10.1093/nar/16.9.4176. [DOI] [PMC free article] [PubMed] [Google Scholar]
  668. van den Berg J., van Ooyen A., Mantei N., Schamböck A., Grosveld G., Flavell R. A., Weissmann C. Comparison of cloned rabbit and mouse beta-globin genes showing strong evolutionary divergence of two homologous pairs of introns. Nature. 1978 Nov 2;276(5683):37–44. doi: 10.1038/276037a0. [DOI] [PubMed] [Google Scholar]
  669. van den Elsen P., Georgopoulos K., Shepley B. A., Orkin S., Terhorst C. Exon/intron organization of the genes coding for the delta chains of the human and murine T-cell receptor/T3 complex. Proc Natl Acad Sci U S A. 1986 May;83(9):2944–2948. doi: 10.1073/pnas.83.9.2944. [DOI] [PMC free article] [PubMed] [Google Scholar]
  670. van den Heuvel R., Hendriks W., Quax W., Bloemendal H. Complete structure of the hamster alpha A crystallin gene. Reflection of an evolutionary history by means of exon shuffling. J Mol Biol. 1985 Sep 20;185(2):273–284. doi: 10.1016/0022-2836(85)90403-6. [DOI] [PubMed] [Google Scholar]
  671. van het Schip A. D., Meijlink F. C., Strijker R., Gruber M., van Vliet A. J., van de Klundert J. A., Ab G. The nucleotide sequence of the chicken apo very low density lipoprotein II gene. Nucleic Acids Res. 1983 May 11;11(9):2529–2540. doi: 10.1093/nar/11.9.2529. [DOI] [PMC free article] [PubMed] [Google Scholar]
  672. van het Schip F. D., Samallo J., Broos J., Ophuis J., Mojet M., Gruber M., AB G. Nucleotide sequence of a chicken vitellogenin gene and derived amino acid sequence of the encoded yolk precursor protein. J Mol Biol. 1987 Jul 20;196(2):245–260. doi: 10.1016/0022-2836(87)90688-7. [DOI] [PubMed] [Google Scholar]

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