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. 1989 Sep 12;17(17):6959–6967. doi: 10.1093/nar/17.17.6959

Forks and combs and DNA: the synthesis of branched oligodeoxyribonucleotides.

T Horn 1, M S Urdea 1
PMCID: PMC318426  PMID: 2780317

Abstract

Nucleoside phosphoramidite derivatives containing two protected primary hydroxyl functions have been incorporated into synthetic oligonucleotides as 'branching monomers'. With selective deprotection, multiple identical copies of an additional oligonucleotide can be incorporated to form fork- or comb-like structures for use as signal amplification materials in nucleic acid hybridization assays.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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