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. 1984 Feb 10;12(3):1641–1655. doi: 10.1093/nar/12.3.1641

Ruminant globin gene structures suggest an evolutionary role for Alu-type repeats.

J C Schimenti, C H Duncan
PMCID: PMC318605  PMID: 6322113

Abstract

Bovine fetal and adult globin genes were cloned and subjected to DNA sequence analysis. Both of these genes contained insertions of Alu-type repetitive DNA within their introns. Comparison of cow and goat beta-type globin genes indicates that intragenic DNA insertions played a role in their evolution. These data support the theory that Alu-type repeats maintain genetic diversity by inhibiting gene conversion.

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Selected References

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