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. 1984 May 25;12(10):4185–4189. doi: 10.1093/nar/12.10.4185

Sequence and structure of a methionine transfer RNA from mosquito mitochondria.

D T Dubin, C C HsuChen
PMCID: PMC318825  PMID: 6328414

Abstract

We have sequenced a methionine tRNA from mosquito mitochondria, and examined its structure using nucleases S1 and T1 under non-denaturing conditions. The sequence is highly homologous to a putative initiator methionine tRNA gene from Drosophila mitochondria. Its anticodon stem contains a run of three G-C base pairs that is characteristic of conventional initiator tRNAs; however, nuclease S1 analysis suggested an anticodon loop configuration characteristic of conventional elongator tRNAs. We propose that this tRNA can assume both initiator and elongator roles.

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Selected References

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