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. 1984 Dec 11;12(23):9209–9226. doi: 10.1093/nar/12.23.9209

Optimizing selection of restriction enzymes in the search for DNA variants.

E M Wijsman
PMCID: PMC320450  PMID: 6096823

Abstract

A model is developed for predicting the relative efficiencies of different enzymes for detecting DNA variants when such variants are the result of single base-pair changes. 71 enzymes are analyzed for this ability in human DNA. Their relative ranked efficiencies are influenced by the sizes of the probes used, and the size of the smallest detectable fragment produced.

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Selected References

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