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. 1985 Dec 9;13(23):8463–8475. doi: 10.1093/nar/13.23.8463

The yeast alpha-factor receptor: structural properties deduced from the sequence of the STE2 gene.

A C Burkholder, L H Hartwell
PMCID: PMC322145  PMID: 3001640

Abstract

The STE2 gene of the yeast Saccharomyces cerevisiae encodes a component of the receptor for the oligopeptide pheromone alpha-factor. We have cloned and determined the nucleotide sequence of the STE2 gene. A sequence involved in the control of cell-type expression of the STE2 gene was found 5' of an open reading frame that could encode a protein of 431 amino acids. The predicted STE2 protein contains seven hydrophobic segments, suggesting that the alpha-factor receptor is an integral membrane protein. No extensive homology at the primary sequence level was detected between the predicted STE2 protein and other available protein sequences.

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Selected References

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