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. 1986 Apr;83(8):2492–2495. doi: 10.1073/pnas.83.8.2492

Evidence for a cellular gene with potential oncogenic activity in plants.

C E Hansen, F Meins Jr
PMCID: PMC323324  PMID: 3458211

Abstract

During tumor inception in crown gall disease, a portion of the tumor-inducing (Ti) plasmid, the transferred DNA (T-DNA), is integrated into the genome of the plant cell. Autonomous growth of the transformants requires expression of genes in the tmr and tms regions of the T-DNA, which code for enzymes concerned with biosynthesis of the plant growth hormones cytokinin and auxin, respectively. We show that a mutation of the Habituated leaf gene, Hl, of tobacco can compensate for a defective tmr locus in expression of the tumor phenotype. This provides evidence that a specific host-cell gene has an oncogenic function similar to tmr in the T-DNA.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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