Skip to main content
PMC home page
The Texas Heart Institute Journal logoLink to The Texas Heart Institute Journal
. 1993;20(3):223–230.

Primary cardiac tumors. A clinical experience of 12 years.

A M Grande 1, T Ragni 1, M Viganò 1
PMCID: PMC325095  PMID: 8219826

Abstract

From January 1980 through December 1992, we performed operations on 31 patients with primary cardiac tumors. There were 12 male and 19 female patients; the ages ranged from 7 to 71 years (mean, 47.7 +/- 18.3 years); 29 were adults and 2 were children. Twenty-six (83.9%) of the tumors were benign, and 5 were malignant. The most frequently encountered benign tumor was myxoma (22), and the most frequently encountered malignant tumor was fibrosarcoma (4). The most common symptoms at clinical presentation were those associated with cardiac insufficiency or embolization. Definition of the tumor was accomplished in all patients by echocardiography; cardiac angiography was performed in only 4 patients. All patients survived the operative procedure and were discharged from the hospital, but 4 patients with malignant disease died within 30 days. Follow-up for myxoma patients ranged from 16 to 151 months (mean, 68.5 +/- 36 months). Among the 26 patients with benign tumors, there was 1 death, 72 months after the surgical procedure, of right-heart failure due to recurrence of the myxoma.

Full text

PDF
228

Images in this article

226Image
on p.226
227Image
on p.227

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Bateman T. M., Gray R. J., Raymond M. J., Chaux A., Czer L. S., Matloff J. M. Arrhythmias and conduction disturbances following cardiac operation for the removal of left atrial myxomas. J Thorac Cardiovasc Surg. 1983 Oct;86(4):601–607. [PubMed] [Google Scholar]
  2. Bortolotti U., Maraglino G., Rubino M., Santini F., Mazzucco A., Milano A., Fasoli G., Livi U., Thiene G., Gallucci V. Surgical excision of intracardiac myxomas: a 20-year follow-up. Ann Thorac Surg. 1990 Mar;49(3):449–453. doi: 10.1016/0003-4975(90)90253-3. [DOI] [PubMed] [Google Scholar]
  3. Bulkley B. H., Hutchins G. M. Atrial myxomas: a fifty year review. Am Heart J. 1979 May;97(5):639–643. doi: 10.1016/0002-8703(79)90193-5. [DOI] [PubMed] [Google Scholar]
  4. Cooley D. A., Reardon M. J., Frazier O. H., Angelini P. Human cardiac explantation and autotransplantation: application in a patient with a large cardiac pheochromocytoma. Tex Heart Inst J. 1985 Jun;12(2):171–176. [PMC free article] [PubMed] [Google Scholar]
  5. Dein J. R., Frist W. H., Stinson E. B., Miller D. C., Baldwin J. C., Oyer P. E., Jamieson S., Mitchell R. S., Shumway N. E. Primary cardiac neoplasms. Early and late results of surgical treatment in 42 patients. J Thorac Cardiovasc Surg. 1987 Apr;93(4):502–511. [PubMed] [Google Scholar]
  6. Desousa A. L., Muller J., Campbell R., Batnitzky S., Rankin L. Atrial myxoma: a review of the neurological complications, metastases, and recurrences. J Neurol Neurosurg Psychiatry. 1978 Dec;41(12):1119–1124. doi: 10.1136/jnnp.41.12.1119. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. Dichek D. A., Holmvang G., Fallon J. T., Kantor H. L., Miller S. W., Dinsmore R. E., Singer D. E., Buckley M. J., Fifer M. A. Angiosarcoma of the heart: three-year survival and follow-up by nuclear magnetic resonance imaging. Am Heart J. 1988 Jun;115(6):1323–1324. doi: 10.1016/0002-8703(88)90034-8. [DOI] [PubMed] [Google Scholar]
  8. Freedberg R. S., Kronzon I., Rumancik W. M., Liebeskind D. The contribution of magnetic resonance imaging to the evaluation of intracardiac tumors diagnosed by echocardiography. Circulation. 1988 Jan;77(1):96–103. doi: 10.1161/01.cir.77.1.96. [DOI] [PubMed] [Google Scholar]
  9. González A., Altieri P. I., Màrquez E. U., Cox R. A., Castillo M. Massive pulmonary embolism associated with a right ventricular myxoma. Am J Med. 1980 Nov;69(5):795–798. doi: 10.1016/0002-9343(80)90455-6. [DOI] [PubMed] [Google Scholar]
  10. Huston K. A., Combs J. J., Jr, Lie J. T., Giuliani E. R. Left atrial myxoma simulating peripheral vasculitis. Mayo Clin Proc. 1978 Nov;53(11):752–756. [PubMed] [Google Scholar]
  11. Larrieu A. J., Jamieson W. R., Tyers G. F., Burr L. H., Munro A. I., Miyagishima R. T., Gerein A. N., Allen P. Primary cardiac tumors: experience with 25 cases. J Thorac Cardiovasc Surg. 1982 Mar;83(3):339–348. [PubMed] [Google Scholar]
  12. Lyons S. V., McCord J., Smith S. Asymptomatic giant right atrial myxoma: role of transesophageal echocardiography in management. Am Heart J. 1991 May;121(5):1555–1558. doi: 10.1016/0002-8703(91)90172-e. [DOI] [PubMed] [Google Scholar]
  13. Marvasti M. A., Obeid A. I., Potts J. L., Parker F. B. Approach in the management of atrial myxoma with long-term follow-up. Ann Thorac Surg. 1984 Jul;38(1):53–58. doi: 10.1016/s0003-4975(10)62186-8. [DOI] [PubMed] [Google Scholar]
  14. Murphy M. C., Sweeney M. S., Putnam J. B., Jr, Walker W. E., Frazier O. H., Ott D. A., Cooley D. A. Surgical treatment of cardiac tumors: a 25-year experience. Ann Thorac Surg. 1990 Apr;49(4):612–618. doi: 10.1016/0003-4975(90)90310-3. [DOI] [PubMed] [Google Scholar]
  15. Obeid A. I., Marvasti M., Parker F., Rosenberg J. Comparison of transthoracic and transesophageal echocardiography in diagnosis of left atrial myxoma. Am J Cardiol. 1989 Apr 15;63(13):1006–1008. doi: 10.1016/0002-9149(89)90162-8. [DOI] [PubMed] [Google Scholar]
  16. Rath S., Har-Zahav Y., Battler A., Agranat O., Neufeld H. N. Coronary arterial embolus from left atrial myxoma. Am J Cardiol. 1984 Dec 1;54(10):1392–1393. doi: 10.1016/s0002-9149(84)80117-4. [DOI] [PubMed] [Google Scholar]
  17. Read R. C., White H. J., Murphy M. L., Williams D., Sun C. N., Flanagan W. H. The malignant potentiality of left atrial myxoma. J Thorac Cardiovasc Surg. 1974 Dec;68(6):857–868. [PubMed] [Google Scholar]
  18. Reece I. J., Cooley D. A., Frazier O. H., Hallman G. L., Powers P. L., Montero C. G. Cardiac tumors. Clinical spectrum and prognosis of lesions other than classical benign myxoma in 20 patients. J Thorac Cardiovasc Surg. 1984 Sep;88(3):439–446. [PubMed] [Google Scholar]
  19. SILVERMAN J., OLWIN J. S., GRAETTINGER J. S. Cardiac myxomas with systemic embolization. Review of the literature and report of a case. Circulation. 1962 Jul;26:99–103. doi: 10.1161/01.cir.26.1.99. [DOI] [PubMed] [Google Scholar]
  20. Samdarshi T. E., Mahan E. F., 3rd, Nanda N. C., Guthrie F. W., Jr, Bernstein I. J., Kirklin J. W. Transesophageal echocardiographic diagnosis of multicentric left ventricular myxomas mimicking a left atrial tumor. J Thorac Cardiovasc Surg. 1992 Mar;103(3):471–474. [PubMed] [Google Scholar]
  21. Topol E. J., Biern R. O., Reitz B. A. Cardiac papillary fibroelastoma and stroke. Echocardiographic diagnosis and guide to excision. Am J Med. 1986 Jan;80(1):129–132. doi: 10.1016/0002-9343(86)90063-x. [DOI] [PubMed] [Google Scholar]
  22. Vergnon J. M., Vincent M., Perinetti M., Loire R., Cordier J. F., Brune J. Chemotherapy of metastatic primary cardiac sarcomas. Am Heart J. 1985 Sep;110(3):682–684. doi: 10.1016/0002-8703(85)90100-0. [DOI] [PubMed] [Google Scholar]
  23. Yamaguchi M., Hosokawa Y., Ohashi H., Imai M., Oshima Y., Minamiji K. Cardiac fibroma. Long-term fate after excision. J Thorac Cardiovasc Surg. 1992 Jan;103(1):140–145. [PubMed] [Google Scholar]
  24. Yang H. Y., Wasielewski J. F., Lee W., Lee E., Paik Y. K. Angiosarcoma of the heart: ultrastructural study. Cancer. 1981 Jan 1;47(1):72–80. doi: 10.1002/1097-0142(19810101)47:1<72::aid-cncr2820470114>3.0.co;2-u. [DOI] [PubMed] [Google Scholar]

Articles from Texas Heart Institute Journal are provided here courtesy of Texas Heart Institute

RESOURCES