Skip to main content
The Texas Heart Institute Journal logoLink to The Texas Heart Institute Journal
. 1991;18(4):263–268.

The Use of Percutaneous Transluminal Coronary Angioplasty in Myocardial Infarction

Donald J McSweyn 1, James L Vacek 1, O Wayne Robuck 1, Loren D Berenbom 1, Charles B Porter 1, Paul H Kramer 1, Randall E Genton 1, Steven K Rowe 1, Gary D Beauchamp 1
PMCID: PMC326350  PMID: 15227408

Abstract

To evaluate the effectiveness of percutaneous transluminal coronary angioplasty (PTCA) in the treatment of myocardial infarction, we reviewed the records of 508 consecutive patients treated within 6 hours of pain onset. Two hundred fifty-eight patients received direct PTCA without thrombolytic therapy, and 250 received thrombolytic therapy followed by immediate PTCA (within 24 hours, n=73) or delayed PTCA (later than 24 hours, n=177). The direct-PTCA group had the lowest initial success rate (92%) and the highest 1-week (8.1%) and 1-year (14%) mortality rates. Immediate PTCA had a 96% success rate, and 6.8% 1-week and 8.2% 1-year mortality rates. Delayed PTCA had the same initial success (96%), but lower 1-week (1.7%) and 1-year (2.3%) mortality. We conclude that both direct PTCA and combination treatment (thrombolytic therapy followed by PTCA) result in high rates of recanalizing occluded coronary arteries, but that combination treatment has higher initial success and survival rates, with delay in the use of PTCA producing the best survival rates. (Texas Heart Institute Journal 1991;18:263-8)

Keywords: Angioplasty, transluminal percutaneous coronary

Keywords: coronary artery bypass

Keywords: heart catheterization

Keywords: myocardial infarction, drug therapy

Keywords: myocardial infarction, mortality

Keywords: thrombolytic therapy

Keywords: survival rate

Full text

PDF
268

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Califf R. M., Topol E. J., Stack R. S., Ellis S. G., George B. S., Kereiakes D. J., Samaha J. K., Worley S. J., Anderson J. L., Harrelson-Woodlief L. Evaluation of combination thrombolytic therapy and timing of cardiac catheterization in acute myocardial infarction. Results of thrombolysis and angioplasty in myocardial infarction--phase 5 randomized trial. TAMI Study Group. Circulation. 1991 May;83(5):1543–1556. doi: 10.1161/01.cir.83.5.1543. [DOI] [PubMed] [Google Scholar]
  2. Grines C. L., DeMaria A. N. Optimal utilization of thrombolytic therapy for acute myocardial infarction: concepts and controversies. J Am Coll Cardiol. 1990 Jul;16(1):223–231. doi: 10.1016/0735-1097(90)90482-5. [DOI] [PubMed] [Google Scholar]
  3. Guerci A. D., Ross R. S. TIMI II and the role of angioplasty in acute myocardial infarction. N Engl J Med. 1989 Mar 9;320(10):663–665. doi: 10.1056/NEJM198903093201009. [DOI] [PubMed] [Google Scholar]
  4. Holmes D. R., Jr, Topol E. J. Reperfusion momentum: lessons from the randomized trials of immediate coronary angioplasty for myocardial infarction. J Am Coll Cardiol. 1989 Nov 15;14(6):1572–1578. doi: 10.1016/0735-1097(89)90401-4. [DOI] [PubMed] [Google Scholar]
  5. Kahn J. K., Rutherford B. D., McConahay D. R., Johnson W. L., Giorgi L. V., Shimshak T. M., Ligon R. W., Hartzler G. O. Catheterization laboratory events and hospital outcome with direct angioplasty for acute myocardial infarction. Circulation. 1990 Dec;82(6):1910–1915. doi: 10.1161/01.cir.82.6.1910. [DOI] [PubMed] [Google Scholar]
  6. Kander N. H., O'Neill W., Topol E. J., Gallison L., Mileski R., Ellis S. G. Long-term follow-up of patients treated with coronary angioplasty for acute myocardial infarction. Am Heart J. 1989 Aug;118(2):228–233. doi: 10.1016/0002-8703(89)90180-4. [DOI] [PubMed] [Google Scholar]
  7. Kennedy J. W., Martin G. V., Davis K. B., Maynard C., Stadius M., Sheehan F. H., Ritchie J. L. The Western Washington Intravenous Streptokinase in Acute Myocardial Infarction Randomized Trial. Circulation. 1988 Feb;77(2):345–352. doi: 10.1161/01.cir.77.2.345. [DOI] [PubMed] [Google Scholar]
  8. Kennedy J. W., Ritchie J. L., Davis K. B., Fritz J. K. Western Washington randomized trial of intracoronary streptokinase in acute myocardial infarction. N Engl J Med. 1983 Dec 15;309(24):1477–1482. doi: 10.1056/NEJM198312153092402. [DOI] [PubMed] [Google Scholar]
  9. O'Keefe J. H., Jr, Rutherford B. D., McConahay D. R., Johnson W. L., Jr, Giorgi L. V., Ligon R. W., Shimshak T. M., Hartzler G. O. Multivessel coronary angioplasty from 1980 to 1989: procedural results and long-term outcome. J Am Coll Cardiol. 1990 Nov;16(5):1097–1102. doi: 10.1016/0735-1097(90)90538-z. [DOI] [PubMed] [Google Scholar]
  10. O'Neill W., Timmis G. C., Bourdillon P. D., Lai P., Ganghadarhan V., Walton J., Jr, Ramos R., Laufer N., Gordon S., Schork M. A. A prospective randomized clinical trial of intracoronary streptokinase versus coronary angioplasty for acute myocardial infarction. N Engl J Med. 1986 Mar 27;314(13):812–818. doi: 10.1056/NEJM198603273141303. [DOI] [PubMed] [Google Scholar]
  11. Rothbaum D. A., Linnemeier T. J., Landin R. J., Steinmetz E. F., Hillis J. S., Hallam C. C., Noble R. J., See M. R. Emergency percutaneous transluminal coronary angioplasty in acute myocardial infarction: a 3 year experience. J Am Coll Cardiol. 1987 Aug;10(2):264–272. doi: 10.1016/s0735-1097(87)80006-2. [DOI] [PubMed] [Google Scholar]
  12. Simoons M. L., Arnold A. E., Betriu A., de Bono D. P., Col J., Dougherty F. C., von Essen R., Lambertz H., Lubsen J., Meier B. Thrombolysis with tissue plasminogen activator in acute myocardial infarction: no additional benefit from immediate percutaneous coronary angioplasty. Lancet. 1988 Jan 30;1(8579):197–203. doi: 10.1016/s0140-6736(88)91062-8. [DOI] [PubMed] [Google Scholar]
  13. Simoons M. L., Serruys P. W., van den Brand M., Res J., Verheugt F. W., Krauss X. H., Remme W. J., Bär F., de Zwaan C., van der Laarse A. Early thrombolysis in acute myocardial infarction: limitation of infarct size and improved survival. J Am Coll Cardiol. 1986 Apr;7(4):717–728. doi: 10.1016/s0735-1097(86)80329-1. [DOI] [PubMed] [Google Scholar]
  14. Stone G. W., Rutherford B. D., McConahay D. R., Johnson W. L., Jr, Giorgi L. V., Ligon R. W., Hartzler G. O. Direct coronary angioplasty in acute myocardial infarction: outcome in patients with single vessel disease. J Am Coll Cardiol. 1990 Mar 1;15(3):534–543. doi: 10.1016/0735-1097(90)90621-u. [DOI] [PubMed] [Google Scholar]
  15. Topol E. J., Califf R. M., George B. S., Kereiakes D. J., Abbottsmith C. W., Candela R. J., Lee K. L., Pitt B., Stack R. S., O'Neill W. W. A randomized trial of immediate versus delayed elective angioplasty after intravenous tissue plasminogen activator in acute myocardial infarction. N Engl J Med. 1987 Sep 3;317(10):581–588. doi: 10.1056/NEJM198709033171001. [DOI] [PubMed] [Google Scholar]
  16. Topol E. J. Coronary angioplasty for acute myocardial infarction. Ann Intern Med. 1988 Dec 15;109(12):970–980. doi: 10.7326/0003-4819-109-12-970. [DOI] [PubMed] [Google Scholar]
  17. Topol E. J., O'Neill W. W., Langburd A. B., Walton J. A., Jr, Bourdillon P. D., Bates E. R., Grines C. L., Schork A. M., Kline E., Pitt B. A randomized, placebo-controlled trial of intravenous recombinant tissue-type plasminogen activator and emergency coronary angioplasty in patients with acute myocardial infarction. Circulation. 1987 Feb;75(2):420–428. doi: 10.1161/01.cir.75.2.420. [DOI] [PubMed] [Google Scholar]

Articles from Texas Heart Institute Journal are provided here courtesy of Texas Heart Institute

RESOURCES