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. 1982 Oct 25;10(20):6243–6254. doi: 10.1093/nar/10.20.6243

Rapid synthesis of oligodeoxyribonucleotides VII. Solid phase synthesis of oligodeoxyribonucleotides by a continuous flow phosphotriester method on a kieselguhr-polyamide support

Michael J Gait 1, Hans WD Matthes 1, Mohinder Singh 1, Brian S Sproat 1, Richard C Titmas 1
PMCID: PMC326914  PMID: 7177846

Abstract

A new kieselguhr-polydimethylacrylamide support has been used in a continuous flow, column system for solid phase synthesis of oligodeoxyribonucleotides by a phosphotriester procedure. Using only protected mononucleotides a 14-mer, 20-mer and 27-mer were assembled in high repetitive yield using a simple manually operated, bench top apparatus.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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