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. 1981 Jul 24;9(14):3219–3233. doi: 10.1093/nar/9.14.3219

Organization of ribosomal RNA gene repeats of the mouse.

R Kominami, Y Urano, Y Mishima, M Muramatsu
PMCID: PMC327348  PMID: 6269075

Abstract

The organization of the ribosomal RNA (rRNA) genes of the mouse was determined by Southern blot hybridization using cloned rDNA fragments as probes, which could encompass the entire spacer region between two rRNA gene regions. The rRNA genes are organized into tandem repeats of nearly uniform length of about 44 kb. The heterogeneity detected in the nontranscribed spacer appears to be caused by its sequence rather than its length difference. At least three kinds of repetitive sequences are present in the non-transcribed spacer region; two of them are located 13 kb upstream from the 5'-end of 18S RNA gene and the other located 1 to 4 kb downstream from the 3'-end of 28S RNA gene.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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