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. 1991 Oct 25;19(20):5613–5617. doi: 10.1093/nar/19.20.5613

Human Alu subfamilies and their methylation revealed by blot hybridization.

C W Schmid 1
PMCID: PMC328965  PMID: 1945838

Abstract

By a simple direct blot hybridization strategy, the existence of human Alu family subfamilies is confirmed. Using consensus restriction cleavage sites, individual bands can be resolved from genomic human DNA digests corresponding to three distinct Alu subfamilies. Digestion with methylation sensitive and insensitive restriction enzymes shows that the numerous CpG residues in the youngest Alu subfamilies are largely methylated in vivo, suggesting a model for the transcriptional regulation of Alu repeats.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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