Skip to main content
Proceedings of the National Academy of Sciences of the United States of America logoLink to Proceedings of the National Academy of Sciences of the United States of America
. 1967 Mar;57(3):782–789. doi: 10.1073/pnas.57.3.782

ENZYMATIC HYDROXYLATION OF PROLINE AND LYSINE IN PROTOCOLLAGEN*

Kari I Kivirikko 1,2,3,4, Darwin J Prockop 1,2,3,4
PMCID: PMC335576  PMID: 16591531

Full text

PDF
783

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Friedman S., Kaufman S. An electron paramagnetic resonance study of 3,4-dihydroxyphenylethylamine beta-hydroxylase. J Biol Chem. 1966 May 25;241(10):2256–2259. [PubMed] [Google Scholar]
  2. Fujimoto D., Tamiya N. Incorporation of O from air into hydroxyproline by chick embryo. Biochem J. 1962 Aug;84(2):333–335. doi: 10.1042/bj0840333. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. GOTTLIEB A. A., PETERKOFSKY B., UDENFRIEND S. USE OF COLLAGENASE TO IDENTIFY ENZYMATICALLY FORMED COLLAGEN AND A HYDROXYPROLINE-DEFICIENT INTERMEDIATE. J Biol Chem. 1965 Jul;240:3099–3103. [PubMed] [Google Scholar]
  4. Hutton J. J., Jr, Trappel A. L., Udenfriend S. Requirements for alpha-ketoglutarate, ferrous ion and ascorbate by collagen proline hydroxylase. Biochem Biophys Res Commun. 1966 Jul 20;24(2):179–184. doi: 10.1016/0006-291x(66)90716-9. [DOI] [PubMed] [Google Scholar]
  5. Hutton J. J., Jr, Udenfriend S. Soluble collagen proline hydroxylase and its substrates in several animal tissues. Proc Natl Acad Sci U S A. 1966 Jul;56(1):198–202. doi: 10.1073/pnas.56.1.198. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. Juva K., Prockop D. J. An effect of puromycin on the synthesis of collagen by embryonic cartilage in vitro. J Biol Chem. 1966 Oct 10;241(19):4419–4425. [PubMed] [Google Scholar]
  7. Juva K., Prockop D. J., Cooper G. W., Lash J. W. Hydroxylation of proline and the intracellular accumulation of a polypeptide precursor of collagen. Science. 1966 Apr 1;152(3718):92–94. doi: 10.1126/science.152.3718.92. [DOI] [PubMed] [Google Scholar]
  8. Juva K., Prockop D. J. Modified procedure for the assay of H-3-or C-14-labeled hydroxyproline. Anal Biochem. 1966 Apr;15(1):77–83. doi: 10.1016/0003-2697(66)90249-1. [DOI] [PubMed] [Google Scholar]
  9. LUKENS L. N. EVIDENCE FOR THE NATURE OF THE PRECURSOR THAT IS HYDROXYLATED DURING THE BIOSYNTHESIS OF COLLAGEN HYDROXYPROLINE. J Biol Chem. 1965 Apr;240:1661–1669. [PubMed] [Google Scholar]
  10. Lukens L. N. The size of the polypeptide precursor of collagen hydroxyproline. Proc Natl Acad Sci U S A. 1966 May;55(5):1235–1243. doi: 10.1073/pnas.55.5.1235. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. PETERKOFSKY B., UDENFRIEND S. CONVERSION OF PROLINE TO COLLAGEN HYDROXYPROLINE IN A CELL-FREE SYSTEM FROM CHICK EMBRYO. J Biol Chem. 1963 Dec;238:3966–3977. [PubMed] [Google Scholar]
  12. PROCKOP D. J., EBERT P. S. A SIMPLE METHOD FOR DIFFERENTIAL ASSAY OF TRITIUM AND CARBON-14 IN WATER-SOLUBLE BIOLOGICAL MATERIALS. Anal Biochem. 1963 Sep;6:263–271. doi: 10.1016/0003-2697(63)90134-9. [DOI] [PubMed] [Google Scholar]
  13. PROCKOP D. J., JUVA K. HYDROXYLATION OF PROLINE IN PARTICULATE FRACTIONS FROM CARTILAGE. Biochem Biophys Res Commun. 1965 Jan 4;18:54–59. doi: 10.1016/0006-291x(65)90881-8. [DOI] [PubMed] [Google Scholar]
  14. PROCKOP D. J., JUVA K. SYNTHESIS OF HYDROXYPROLINE IN VITRO BY THE HYDROXYLATION OF PROLINE IN A PRECURSOR OF COLLAGEN. Proc Natl Acad Sci U S A. 1965 Mar;53:661–668. doi: 10.1073/pnas.53.3.661. [DOI] [PMC free article] [PubMed] [Google Scholar]
  15. PROCKOP D. J., UDENFRIEND S. A specific method for the analysis of hydroxyproline in tissues and urine. Anal Biochem. 1960 Nov;1:228–239. doi: 10.1016/0003-2697(60)90050-6. [DOI] [PubMed] [Google Scholar]
  16. Popenoe E. A., Aronson R. B., Van Slyke D. D. Hydroxylysine formation from lysine during collagen biosynthesis. Proc Natl Acad Sci U S A. 1966 Feb;55(2):393–397. doi: 10.1073/pnas.55.2.393. [DOI] [PMC free article] [PubMed] [Google Scholar]
  17. Prockop D. J., Weinstein E., Mulveny T. Hydroxylation of lysine in a polypeptide precursor of collagen. Biochem Biophys Res Commun. 1966 Jan 4;22(1):124–128. doi: 10.1016/0006-291x(66)90613-9. [DOI] [PubMed] [Google Scholar]
  18. SINEX F. M., VAN SLYKE D. D., CHRISTMAN D. R. The source and state of the hydroxylysine of collagen. II. Failure of free hydroxylysine to serve as a source of the hydroxylysine or lysine of collagen. J Biol Chem. 1959 Apr;234(4):918–921. [PubMed] [Google Scholar]
  19. STETTEN M. R. Some aspects of the metabolism of hydroxyproline, studied with the aid of isotopic nitrogen. J Biol Chem. 1949 Nov;181(1):31–37. [PubMed] [Google Scholar]

Articles from Proceedings of the National Academy of Sciences of the United States of America are provided here courtesy of National Academy of Sciences

RESOURCES