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. 1970 Aug;66(4):1267–1274. doi: 10.1073/pnas.66.4.1267

GENETIC CONTROL OF THE IMMUNE RESPONSE OF GUINEA PIGS TO LIMITING DOSES OF BOVINE SERUM ALBUMIN: RELATIONSHIP TO THE POLY-L-LYSINE GENE

I Green 1,*, J K Inman 1, B Benacerraf 1
PMCID: PMC335815  PMID: 5273452

Abstract

The response of strain 2 guinea pigs to limiting doses of bovine serum albumin is under dominant genetic control linked with the poly-L-lysine gene. Inbred strains 2 and 13 guinea pigs make similar antibody responses to 10 μg bovine serum albumin, whereas strain 2 but not strain 13 animals produce significant amounts of antibodies in response to 0.1 μg. The relationship between the presence of the poly-L-lysine gene and the ability to respond to limiting doses of bovine serum albumin has also been investigated in random-bred Hartley strain guinea pigs.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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