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. 1978 Sep;75(9):4479–4483. doi: 10.1073/pnas.75.9.4479

Selective association of murine T lymphoblastoid cell surface alloantigens with Mycoplasma hyorhinis.

K S Wise, G H Cassell, R T Action
PMCID: PMC336139  PMID: 212754

Abstract

Mycoplasma hyorhinis, isolated by isopycnic centrifugation from supernatants of a persistently infected murine T lymphoblastoid cell line, demonstrated the presence of the Thy-1.1 differentiation alloantigen and H-2Kk histocompatibility antigens. The murine leukemia virus-related gp70 antigen also present on the surface of these lymphoblastoid cells was absent from mycoplasma preparations. Quantitative assessment of Thy-1.1 present in preparations of M. hyorhinis revealed a specific activity greater or equal to that of membrane preparations from lymphoblastoid cells, suggesting a marked accumulation of this T lymphoblastoid cells, suggesting a marked accumulation of this T lymphocyte antigen by membrane-associated mycoplasmas. The accumulation of the Thy-1.1 antigen in association with purified mycoplasmas was also demonstrated in lymphoblastoid cells experimentally infected with a defined culture of M. hyorhinis.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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