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. 1988 Jun 10;16(11):5031–5038. doi: 10.1093/nar/16.11.5031

The relative importance of Escherichia coli exonuclease III and endonuclease IV for the hydrolysis of 3'-phosphoglycolate ends in polydeoxynucleotides.

B Siwek 1, S Bricteux-Grégoire 1, V Bailly 1, W G Verly 1
PMCID: PMC336714  PMID: 2455278

Abstract

In vitro, in the presence of Mg++, the 3'-phosphoglycolatase activity of endonuclease IV is about 4-times smaller than that of exonuclease III for the same AP endonuclease activity. It thus seems that endonuclease IV has only a minor role in the repair of strand breaks limited by 3'-phosphoglycolate ends in Escherichia coli even after the amount of enzyme has been increased by induction with O2 -generating agents.

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Selected References

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