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. 1987 Dec 23;15(24):10455–10467. doi: 10.1093/nar/15.24.10455

Nucleotide sequence of the regulatory locus controlling expression of bacterial genes for bioluminescence.

J Engebrecht 1, M Silverman 1
PMCID: PMC339955  PMID: 3697093

Abstract

Production of light by the marine bacterium Vibrio fischeri and by recombinant hosts containing cloned lux genes is controlled by the density of the culture. Density-dependent regulation of lux gene expression has been shown to require a locus consisting of the luxR and luxI genes and two closely linked divergent promoters. As part of a genetic analysis to understand the regulation of bioluminescence, we have sequenced the region of DNA containing this control circuit. Open reading frames corresponding to luxR and luxI were identified; transcription start sites were defined by S1 nuclease mapping and sequences resembling promoter elements were located.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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