Skip to main content
PMC home page
Nucleic Acids Research logoLink to Nucleic Acids Research
. 1985 Jan 11;13(1):251–260. doi: 10.1093/nar/13.1.251

The infrared spectrum and structure of the type I complex of silver and DNA.

D E DiRico Jr, P B Keller, K A Hartman
PMCID: PMC340988  PMID: 4000921

Abstract

Infrared spectroscopy was used to study films of the type I complex of Ag+ and DNA as a function of hydration with the following conclusions. Ag+ binds to guanine residues but not to cytosine or thymine residues. Cytosine becomes protonated as Ag+ binds to guanine. (These conclusions confirm previous models.) The type I complex remains in the B family of structures with slight modifications of the sugar-phosphate geometry. This modified B structure remains stable at lower values of hydration for which pure DNA is in the A form. Binding of Ag+ to PO2-, O-P-O or the deoxyribose oxygen is excluded.

Full text

PDF
252

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Casadevall A., Day L. A. Silver and mercury probing of deoxyribonucleic acid structures in the filamentous viruses fd, If1, IKe, Xf, Pf1, and Pf3. Biochemistry. 1983 Sep 27;22(20):4831–4842. doi: 10.1021/bi00289a033. [DOI] [PubMed] [Google Scholar]
  2. Champeil P., Tran T. P., Brahms J. A new approach to the characterization of the B and A forms of DNA by I.R. spectroscopy. Biochem Biophys Res Commun. 1973 Dec 10;55(3):881–887. doi: 10.1016/0006-291x(73)91226-6. [DOI] [PubMed] [Google Scholar]
  3. Dattagupta N., Crothers D. M. Solution structural studies of the Ag(I)-DNA complex. Nucleic Acids Res. 1981 Jun 25;9(12):2971–2985. doi: 10.1093/nar/9.12.2971. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Dickerson R. E., Drew H. R., Conner B. N., Wing R. M., Fratini A. V., Kopka M. L. The anatomy of A-, B-, and Z-DNA. Science. 1982 Apr 30;216(4545):475–485. doi: 10.1126/science.7071593. [DOI] [PubMed] [Google Scholar]
  5. Ding D., Allen F. S. A circular dichroism study on the structure of DNA and the nucleosomal core particle using Hg(II) and Ag(I). Biochim Biophys Acta. 1980 Nov 14;610(1):72–80. doi: 10.1016/0005-2787(80)90057-x. [DOI] [PubMed] [Google Scholar]
  6. Ding D., Allen F. S. Electric dichroism and sedimentation velocity studies of DNA-Hg(II) and DNA-Ag(I) complexes. Biochim Biophys Acta. 1980 Nov 14;610(1):64–71. doi: 10.1016/0005-2787(80)90056-8. [DOI] [PubMed] [Google Scholar]
  7. HARTMAN K. A., Jr, RICH A. THE TAUTOMERIC FORM OF HELICAL POLYRIBOCYTIDYLIC ACID. J Am Chem Soc. 1965 May 5;87:2033–2039. doi: 10.1021/ja01087a031. [DOI] [PubMed] [Google Scholar]
  8. Hartman K. A., Jr The infrared spectra of some complexes of metal ions with nucleotides. Biochim Biophys Acta. 1967 Mar 29;138(1):192–195. doi: 10.1016/0005-2787(67)90601-6. [DOI] [PubMed] [Google Scholar]
  9. Luk K. F., Maki A. H., Hoover R. J. Letter: Studies of heavy metal binding with polynucleotides using optical detection of magnetic resonance. Silver(I) binding. J Am Chem Soc. 1975 Mar 5;97(5):1241–1242. doi: 10.1021/ja00838a047. [DOI] [PubMed] [Google Scholar]
  10. MILES H. T. Tautomeric forms in a polynucleotide helix and their bearing on the structure of DNA. Proc Natl Acad Sci U S A. 1961 Jun 15;47:791–802. doi: 10.1073/pnas.47.6.791. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. Pohle W., Fritzsche H. A new conformation-specific infrared band of A-DNA in films. Nucleic Acids Res. 1980 Jun 11;8(11):2527–2535. doi: 10.1093/nar/8.11.2527. [DOI] [PMC free article] [PubMed] [Google Scholar]
  12. Sirover M. A., Loeb L. A. Infidelity of DNA synthesis in vitro: screening for potential metal mutagens or carcinogens. Science. 1976 Dec 24;194(4272):1434–1436. doi: 10.1126/science.1006310. [DOI] [PubMed] [Google Scholar]
  13. Taillandier E., Fort L., Liquier J., Couppez M., Sautiere P. Role of the protein alpha helixes in histone-DNA interactions studied by vibrational spectroscopy. Biochemistry. 1984 Jun 5;23(12):2644–2650. doi: 10.1021/bi00307a016. [DOI] [PubMed] [Google Scholar]
  14. Zavriev S. K., Minchenkova L. E., Vorlícková M., Kolchinsky A. M., Volkenstein M. V., Ivanov V. I. Circular dichroism anisotrophy of DNA with different modifications at N7 of guanine. Biochim Biophys Acta. 1979 Sep 27;564(2):212–224. doi: 10.1016/0005-2787(79)90220-x. [DOI] [PubMed] [Google Scholar]

Articles from Nucleic Acids Research are provided here courtesy of Oxford University Press

RESOURCES