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. 1985 Apr 11;13(7):2583–2601. doi: 10.1093/nar/13.7.2583

Novel non-suppressing mutants of Escherichia coli tRNATyr su+3.

P Furdon, S Altman
PMCID: PMC341177  PMID: 3889847

Abstract

Several addition and deletion mutations were constructed in the region of the gene for Escherichia coli tRNATyr su+3 corresponding to the dihydrouracil loop of the mature tRNA. None of these resulting mutants had detectable suppressor function compared to the parent gene yet some directed the synthesis of mature tRNA. These latter mutants may affect the ability of the tRNA to be aminoacylated or to interact with the translational machinery on the ribosome.

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Selected References

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