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. 1985 May 24;13(10):3635–3649. doi: 10.1093/nar/13.10.3635

Synthesis of riboguanosine pentaphosphate ppprGpp (Magic Spot II) via a phosphotriester approach.

C Schattenkerk, C T Wreesmann, G A van der Marel, J H van Boom
PMCID: PMC341263  PMID: 4011437

Abstract

The bifunctional phosphorylating reagent O,O-bis[1-benzotriazolyl]phosphoromorpholidate was used to introduce a 5'-O-triphosphate and a 3'-O-diphosphate function in a partially protected riboguanosine. Pilot studies indicated that protection of the 2'-OH of ribonucleosides with the acid-labile tetrahydropyranyl group, instead of the more labile 4-methoxytetrahydropyran-4-yl group, was most satisfactory for the preparation of the Magic Spot II.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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